日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human autoimmunity at single cell resolution in aplastic anemia before and after effective immunotherapy

有效免疫治疗前后再生障碍性贫血中单细胞分辨率的人类自身免疫

Zhijie Wu # ,Shouguo Gao # ,Xingmin Feng # ,Haoran Li ,Nicolas Sompairac ,Shirin Jamshidi ,Desmond Choy ,Rita Antunes Dos Reis ,Qingyan Gao ,Sachiko Kajigaya ,Lemlem Alemu ,Diego Quinones Raffo ,Emma M Groarke ,Shahram Kordasti ,Bhavisha A Patel ,Neal S Young

In depth transcriptomic profiling defines a landscape of dysfunctional immune responses in patients with VEXAS syndrome

深入的转录组分析揭示了VEXAS综合征患者免疫反应功能障碍的全貌。

Hiroki Mizumaki # ,Shouguo Gao # ,Zhijie Wu ,Fernanda Gutierrez-Rodrigues ,Massimiliano Bissa ,Xingmin Feng ,Emma M Groarke ,Haoran Li ,Lemlem Alemu ,Diego Quinones Raffo ,Ivana Darden ,Sachiko Kajigaya ,Peter C Grayson ,Genoveffa Franchini ,Neal S Young ,Bhavisha A Patel

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

STAT5B 白血病突变会改变 SH2 酪氨酸 665,对免疫基因程序产生相反的影响

Hye Kyung Lee, Jichun Chen, Rachael L Philips, Sung-Gwon Lee, Xingmin Feng, Zhijie Wu, Chengyu Liu, Aaron B Schultz, Molly Dalzell, Foster Birnbaum, Joel A Sexton, Amy E Keating, John J O'Shea, Neal S Young, Alejandro V Villarino, Priscilla A Furth, Lothar Hennighausen

Efficacy of JAK1/2 inhibition in murine immune bone marrow failure

JAK1/2 抑制对小鼠免疫性骨髓衰竭的疗效

Emma M Groarke, Xingmin Feng, Nidhi Aggarwal, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Bhavisha A Patel, Jichun Chen, Neal S Young

Early activation of inflammatory pathways in UBA1-mutated hematopoietic stem and progenitor cells in VEXAS

VEXAS 中 UBA1 突变的造血干细胞和祖细胞中炎症通路早期激活

Zhijie Wu ,Shouguo Gao ,Qingyan Gao ,Bhavisha A Patel ,Emma M Groarke ,Xingmin Feng ,Ash Lee Manley ,Haoran Li ,Daniela Ospina Cardona ,Sachiko Kajigaya ,Lemlem Alemu ,Diego Quinones Raffo ,Amanda K Ombrello ,Marcela A Ferrada ,Peter C Grayson ,Katherine R Calvo ,Daniel L Kastner ,David B Beck ,Neal S Young

Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells

单细胞 RNA 测序与大颗粒淋巴细胞白血病 T 细胞的 TCR 分析相结合

Shouguo Gao #, Zhijie Wu #, Bradley Arnold, Carrie Diamond, Sai Batchu, Valentina Giudice, Lemlem Alemu, Diego Quinones Raffo, Xingmin Feng, Sachiko Kajigaya, John Barrett, Sawa Ito, Neal S Young

Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia

抗 COX-2 自身抗体是免疫性再生障碍性贫血的新型生物标志物

Tiina Kelkka, Mikko Tyster, Sofie Lundgren #, Xingmin Feng #, Cassandra Kerr #, Kohei Hosokawa #, Jani Huuhtanen #, Mikko Keränen, Bhavisha Patel, Toru Kawakami, Yuka Maeda, Otso Nieminen, Tiina Kasanen, Pasi Aronen, Bhagwan Yadav, Hanna Rajala, Hideyuki Nakazawa, Taina Jaatinen, Eva Hellström-Lindb

Conditional deletion of mTOR discloses its essential role in early B-cell development

条件性敲除 mTOR 揭示了其在早期 B 细胞发育中的关键作用

Shuling Zhang ,Wendy Dubois ,Xingmin Feng ,Joe T Nguyen ,Neal S Young ,Beverly A Mock

Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults

雷帕霉素可增强造血损伤后的造血干细胞和祖细胞再生

Zenghua Lin, Maile K Hollinger, Zhijie Wu, Wanling Sun, Kaylind Batey, Jisoo Kim, Jichun Chen, Xingmin Feng, Neal S Young

Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis

通过人类和小鼠单细胞 RNA 测序进行综合网络建模,揭示了造血过程中高度保守的转录调控

Shouguo Gao, Zhijie Wu, Xingmin Feng, Sachiko Kajigaya, Xujing Wang, Neal S Young