Xiu-Rong Ren相关文献与解析，生知库 | 链接生命科学的每一步

Jiangbo Wang, Xiu-Rong Ren, Hailan Piao, Shengli Zhao, Takuya Osada, Richard T Premont, Robert A Mook Jr, Michael A Morse, Herbert Kim Lyerly, Wei Chen

信号转导

肿瘤

肠癌

Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth

鉴定出DK419，一种强效的Wnt/β-catenin信号通路和结直肠癌生长抑制剂。

期刊:Bioorganic & Medicinal Chemistry

影响因子:3.3

doi:10.1016/j.bmc.2018.09.016

Jiangbo Wang ,Robert A Mook Jr ,Xiu-Rong Ren ,Qingfu Zhang ,Genevieve Jing ,Min Lu ,Ivan Spasojevic ,H Kim Lyerly ,David Hsu ,Wei Chen

Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis

苯并咪唑类药物 Niclosamide 化学型可选择性抑制 Wnt/β-catenin 信号传导，而非影响 ATP 稳态

期刊:Bioorganic & Medicinal Chemistry

影响因子:3.3

doi:10.1016/j.bmc.2017.01.046

Robert A Mook Jr, Xiu-Rong Ren, Jiangbo Wang, Hailan Piao, Larry S Barak, H Kim Lyerly, Wei Chen

Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure

氯硝柳胺化学型中 Wnt/β-catenin 抑制的结构活性研究：鉴定具有改善药物暴露的衍生物

期刊:Bioorganic & Medicinal Chemistry

影响因子:3.3

doi:10.1016/j.bmc.2015.07.001

Robert A Mook Jr, Jiangbo Wang, Xiu-Rong Ren, Minyong Chen, Ivan Spasojevic, Larry S Barak, H Kim Lyerly, Wei Chen

MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro

MARCKS 和 HSP70 相互作用调节人气道上皮细胞体外粘蛋白的分泌

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology

影响因子:3.6

doi:10.1152/ajplung.00337.2012

Shijing Fang, Anne L Crews, Wei Chen, Joungjoa Park, Qi Yin, Xiu-Rong Ren, Kenneth B Adler

Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells

疫苗诱导的多克隆 HER2 特异性抗体介导肿瘤细胞中的受体内化和降解

期刊:Breast Cancer Research

影响因子:6.1

doi:10.1186/bcr3204

Xiu-Rong Ren, Junping Wei, Gangjun Lei, Jiangbo Wang, Jiuyi Lu, Wenle Xia, Neil Spector, Larry S Barak, Timothy M Clay, Takuya Osada, Erika Hamilton, Kimberly Blackwell, Amy C Hobeika, Michael A Morse, H Kim Lyerly, Wei Chen

Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo

体内 HER2 免疫和药物联合抑制的协同作用

期刊:International Journal of Cancer

影响因子:5.7

doi:10.1002/ijc.24995

Michael A Morse, Junping Wei, Zachary Hartman, Wenle Xia, Xiu-Rong Ren, Gangjun Lei, William T Barry, Takuya Osada, Amy C Hobeika, Sharon Peplinski, Haixiang Jiang, Gayathri R Devi, Wei Chen, Neil Spector, Andrea Amalfitano, H Kim Lyerly, Timothy M Clay

The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling

抗蠕虫药氯硝柳胺抑制 Wnt/Frizzled1 信号传导

期刊:Biochemistry

影响因子:2.9

doi:10.1021/bi9009677

Minyong Chen, Jiangbo Wang, Jiuyi Lu, Michael C Bond, Xiu-Rong Ren, H Kim Lyerly, Larry S Barak, Wei Chen

Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy

氯硝柳胺诱导的结肠直肠癌 Wnt 信号抑制由自噬介导

Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth

鉴定出DK419，一种强效的Wnt/β-catenin信号通路和结直肠癌生长抑制剂。

Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis

苯并咪唑类药物 Niclosamide 化学型可选择性抑制 Wnt/β-catenin 信号传导，而非影响 ATP 稳态

Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure

氯硝柳胺化学型中 Wnt/β-catenin 抑制的结构活性研究：鉴定具有改善药物暴露的衍生物

MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro

MARCKS 和 HSP70 相互作用调节人气道上皮细胞体外粘蛋白的分泌

Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells

疫苗诱导的多克隆 HER2 特异性抗体介导肿瘤细胞中的受体内化和降解

Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo

体内 HER2 免疫和药物联合抑制的协同作用

The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling

抗蠕虫药氯硝柳胺抑制 Wnt/Frizzled1 信号传导