日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proinflammatory GSDMD activation in live macrophages and DLBCL cells marks cognate interactions and better prognosis

活巨噬细胞和弥漫性大B细胞淋巴瘤细胞中促炎性GSDMD的激活标志着同源相互作用和更好的预后。

Kong, Xue; Xu-Monette, Zijun Y; Xu, Zhenming; Hsi, Eric D; Zhao, Xiaoxian; Yan, Hui; Nunns, Harry; Au, Kelly; Visco, Carlo; Tzankov, Alexandar; Dybkaer, Karen; Yao, Shuna; Wu, Dehong; Wang, Chang; Xu, Alexander M; Pan, Zenggang; Parsons, Benjamin M; Chiu, April; Tam, Wayne; Montes-Moreno, Santiago; Zhan, Fenghuang; Bernal-Mizrachi, Leon; Zu, Youli; Zhang, Shanxiang; Møller, Michael B; Chen, Weina; Au, Qingyan; Merchant, Akil; Bhagat, Govind; Li, Yong; Young, Ken H

Mutational profiling of HIV+ diffuse large B-cell lymphoma reveals distinct mutational features with evidence of genomic instability

HIV阳性弥漫性大B细胞淋巴瘤的突变谱分析揭示了独特的突变特征,并有基因组不稳定性证据。

Roush, Sophia M; Beck, Samantha; Coelho, Jenny; Chirwa, Amon; Mponda, Marriam; Kasonkanji, Edwards; Mulenga, Maurice; Tomoka, Tamiwe; Vensko, Steven; Merchant, Akil; Xu, Alexander M; Wang, Jeremy R; Galeotti, Jonathan; Gopal, Satish; Yates, Melinda; Broaddus, Russell; Painschab, Matthew S; Fedoriw, Yuri

Identifying perturbations that boost T-cell infiltration into tumours via counterfactual learning of their spatial proteomic profiles

通过反事实学习肿瘤空间蛋白质组学特征,识别促进T细胞浸润肿瘤的扰动因素。

Wang, Zitong Jerry; Farooq, Abdullah S; Chen, Yu-Jen; Bhargava, Aman; Xu, Alexander M; Thomson, Matt W

Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment.

脂肪肝中转移性肿瘤的生长是由 HAS2 介导的纤维化肿瘤微环境促进的

Yang Yoon Mee, Kim Jieun, Wang Zhijun, Kim Jina, Kim So Yeon, Cho Gyu Jeong, Lee Jee Hyung, Kim Sun Myoung, Tsuchiya Takashi, Matsuda Michitaka, Pandyarajan Vijay, Pandol Stephen J, Lewis Michael S, Gangi Alexandra, Noble Paul W, Jiang Dianhua, Merchant Akil, Posadas Edwin M, Bhowmick Neil A, Lu Shelly C, You Sungyong, Xu Alexander M, Seki Ekihiro

High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics

未另行规定的高级别B细胞淋巴瘤,具有弥漫性大B细胞淋巴瘤基因表达特征:基因组分析和潜在治疗方法

Lone, Waseem; Bouska, Alyssa; Herek, Tyler A; Amador, Catalina; Song, Joo; Xu, Alexander M; Jochum, Dylan; Issa, Issa Ismail; Weisenburger, Dennis D; Zhang, Xuan; Bhagavathi, Sharath Kumar; Heavican-Foral, Tayla B; Sharma, Sunandini; Shah, Ab Rauf; Mir, Abdul Rouf; Alkhinji, Aisha Ahmad; El-Gamal, Dalia; Dave, Bhavana J; Hartert, Keenan; Yu, Jiayu; Saumyaranjan, Mallick; Greiner, Timothy C; Vose, Julie; McKeithan, Timothy W; Fu, Kai; Green, Michael; Bi, Chengfeng; Merchant, Akil; Chan, Wing C; Iqbal, Javeed

Pre-vaccine immune profiling in cancer patients identifies correlates of COVID-19 vaccine responses

癌症患者接种疫苗前的免疫特征分析可识别出与新冠疫苗反应相关的因素

Kazerani, Maryam; Mahov, Simeon; Foley, Joslyn; Merin, Noah M; Choi, So Yung; Lownik, Joseph; Xu, Alexander M; Milshteyn, Larry; Villamejor, Anton Luis; Nadri, Maimoona; Nguyen, Nathalie; Kazemian, Elham; Hamid, Omid; Darrah, Justin; Gong, Jun; Paquette, Ronald; Vescio, Robert; Mehmi, Inderjit; Tourtellotte, Warren G; Ramanujan, V Krishnan; Reckamp, Karen L; Figueiredo, Jane C; Merchant, Akil

Low booster uptake in cancer patients despite health benefits

尽管有健康益处,但癌症患者对加强针的接受度仍然很低,而加强针的使用率却很低。

Figueiredo, Jane C; Levy, Julia; Choi, So Yung; Xu, Alexander M; Merin, Noah M; Hamid, Omid; Lemos, Tucker; Nguyen, Nathalie; Nadri, Maimoona; Gonzalez, Alma; Mahov, Simeon; Darrah, Justin M; Gong, Jun; Paquette, Ronald L; Mita, Alain C; Vescio, Robert A; Salvy, Sarah J; Mehmi, Inderjit; Hendifar, Andrew E; Natale, Ronald; Tourtellotte, Warren G; Ramanujan, V Krishnan; Huynh, Carissa A; Sobhani, Kimia; Reckamp, Karen L; Merchant, Akil A

HIV and prior exposure to antiretroviral therapy alter tumour composition and tumour: T-cell associations in diffuse large B-cell lymphoma

HIV感染和既往抗逆转录病毒治疗史会改变弥漫性大B细胞淋巴瘤的肿瘤组成和肿瘤:T细胞关联

Coelho, Jenny; Roush, Sophia M; Xu, Alexander M; Puranam, Kaushik; Mponda, Marriam; Kasonkanji, Edwards; Mulenga, Maurice; Tomoka, Tamiwe; Galeotti, Jonathan; Brownlee, Amy; Ghadially, Hormas; Damania, Blossom; Painschab, Matthew; Merchant, Akil; Gopal, Satish; Fedoriw, Yuri

Differences in SARS-CoV-2 Vaccine Response Dynamics Between Class-I- and Class-II-Specific T-Cell Receptors in Inflammatory Bowel Disease

炎症性肠病中I类和II类特异性T细胞受体对SARS-CoV-2疫苗反应动力学的差异

Xu, Alexander M; Li, Dalin; Ebinger, Joseph E; Mengesha, Emebet; Elyanow, Rebecca; Gittelman, Rachel M; Chapman, Heidi; Joung, Sandy; Botwin, Gregory J; Pozdnyakova, Valeriya; Debbas, Philip; Mujukian, Angela; Prostko, John C; Frias, Edwin C; Stewart, James L; Horizon, Arash A; Merin, Noah; Sobhani, Kimia; Figueiredo, Jane C; Cheng, Susan; Kaplan, Ian M; McGovern, Dermot P B; Merchant, Akil; Melmed, Gil Y; Braun, Jonathan

Fabrication of Sealed Nanostraw Microdevices for Oral Drug Delivery

用于口服药物递送的密封纳米吸管微器件的制备

Fox, Cade B; Cao, Yuhong; Nemeth, Cameron L; Chirra, Hariharasudhan D; Chevalier, Rachel W; Xu, Alexander M; Melosh, Nicholas A; Desai, Tejal A