Xu Guanlan相关文献与解析，生知库 | 链接生命科学的每一步

Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

维拉帕米可预防1型糖尿病患者IGF-I水平下降并促进β细胞IGF-I信号传导

期刊:Diabetes

影响因子:7.5

doi:10.2337/db23-0256

Xu, Guanlan; Chen, Junqin; Lu, Brian; Sethupathy, Praveen; Qian, Wei-Jun; Shalev, Anath

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

探索性研究揭示了维拉帕米治疗对1型糖尿病患者的深远全身性和细胞性影响

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-022-28826-3

Xu, Guanlan; Grimes, Tiffany D; Grayson, Truman B; Chen, Junqin; Thielen, Lance A; Tse, Hubert M; Li, Peng; Kanke, Matt; Lin, Tai-Tu; Schepmoes, Athena A; Swensen, Adam C; Petyuk, Vladislav A; Ovalle, Fernando; Sethupathy, Praveen; Qian, Wei-Jun; Shalev, Anath

Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss.

血清 miR-204 是 1 型糖尿病相关胰岛 β 细胞丢失的早期生物标志物

期刊:American Journal of Physiology-Endocrinology and Metabolism

影响因子:3.1

doi:10.1152/ajpendo.00122.2019

Xu Guanlan, Thielen Lance A, Chen Junqin, Grayson Truman B, Grimes Tiffany, Bridges S Louis Jr, Tse Hubert M, Smith Blair, Patel Rakesh, Li Peng, Evans-Molina Carmella, Ovalle Fernando, Shalev Anath

Verapamil and beta cell function in adults with recent-onset type 1 diabetes

维拉帕米对近期发病的1型糖尿病成人患者β细胞功能的影响

期刊:Nature Medicine

影响因子:50

doi:10.1038/s41591-018-0089-4

Ovalle, Fernando; Grimes, Tiffany; Xu, Guanlan; Patel, Anish J; Grayson, Truman B; Thielen, Lance A; Li, Peng; Shalev, Anath

Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2

硫氧还蛋白相互作用蛋白通过 miR-124a 和 FoxA2 促进胰岛淀粉样多肽的表达

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M113.525022

Jing, Gu; Westwell-Roper, Clara; Chen, Junqin; Xu, Guanlan; Verchere, C Bruce; Shalev, Anath

发表日期：2014

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MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis

MicroRNA-200 由硫氧还蛋白相互作用蛋白诱导，并调节 Zeb1 蛋白信号传导和 β 细胞凋亡。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M114.592360

Filios, Stephen R; Xu, Guanlan; Chen, Junqin; Hong, Kyunghee; Jing, Gu; Shalev, Anath

FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells

FOXO1与碳水化合物反应元件结合蛋白（ChREBP）竞争，并抑制胰岛β细胞中硫氧还蛋白相互作用蛋白（TXNIP）的转录。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M113.473082

Kibbe, Carly; Chen, Junqin; Xu, Guanlan; Jing, Gu; Shalev, Anath

Preventing β-cell loss and diabetes with calcium channel blockers

利用钙通道阻滞剂预防β细胞丢失和糖尿病

期刊:Diabetes

影响因子:7.5

doi:10.2337/db11-0955

Xu, Guanlan; Chen, Junqin; Jing, Gu; Shalev, Anath

Oral TIX100 protects against obesity-associated glucose intolerance and diet-induced adiposity.

口服 TIX100 可预防肥胖相关的葡萄糖耐受不良和饮食引起的脂肪堆积

Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

维拉帕米可预防1型糖尿病患者IGF-I水平下降并促进β细胞IGF-I信号传导

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

探索性研究揭示了维拉帕米治疗对1型糖尿病患者的深远全身性和细胞性影响

Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss.

血清 miR-204 是 1 型糖尿病相关胰岛 β 细胞丢失的早期生物标志物

Verapamil and beta cell function in adults with recent-onset type 1 diabetes

维拉帕米对近期发病的1型糖尿病成人患者β细胞功能的影响

Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2

硫氧还蛋白相互作用蛋白通过 miR-124a 和 FoxA2 促进胰岛淀粉样多肽的表达

MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis

MicroRNA-200 由硫氧还蛋白相互作用蛋白诱导，并调节 Zeb1 蛋白信号传导和 β 细胞凋亡。

FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells

FOXO1与碳水化合物反应元件结合蛋白（ChREBP）竞争，并抑制胰岛β细胞中硫氧还蛋白相互作用蛋白（TXNIP）的转录。

Preventing β-cell loss and diabetes with calcium channel blockers

利用钙通道阻滞剂预防β细胞丢失和糖尿病