日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of N-Nitrosamines

调整预孵育条件以增强Ames试验检测N-亚硝胺致突变性的能力

Bishop, Michelle E; Sims, Audrey M; Guerrero, Sharon K; Mitchell, Kamela; Mei, Nan; Xu, Hannah; Kruhlak, Naomi L; King, Sruthi T; Dorsam, Robert T; Atrakchi, Aisar H; McGovern, Timothy J; Heflich, Robert H

Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1.

利用有机核心高密度脂蛋白样纳米颗粒封装和递送激酶抑制剂PIK-75靶向清道夫受体B类1型

Rink Jonathan S, Lin Adam Y, Calvert Andrea E, Kwon David, Moxley Alexandra, Henrich Stephen E, Mohammadlou Aliakbar, Zhang Xu Hannah, Wu Xiwei, Querfeld Christiane, Griend Donald J Vander, Yin Hongwei Holly, Horne David A, Nguyen SonBinh T, Rosen Steven T, Gordon Leo I, Thaxton Colby Shad

Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages

鉴定脂质相关巨噬细胞的保守性和组织特异性转录谱

Yingzheng Xu ,Hannah Hillman ,Michael Chang ,Fanta Barrow ,Stoyan Ivanov ,Xavier S Revelo ,Jesse W Williams

Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities

将大鼠肝微核试验整合到 28 天治疗方案中:测试 4 种具有不同致癌效力和肿瘤靶向特异性的小分子亚硝胺的遗传毒性

Guo, Xiaoqing; Seo, Ji-Eun; Xu, Hannah; Yan, Jian; Malhi, Pritpal; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Heflich, Robert H; Chen, Tao

Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models

利用二维和三维HepaRG细胞模型对十种亚硝胺类药物相关杂质进行遗传毒性评价

Seo, Ji-Eun; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Keire, David A; Mei, Nan; Heflich, Robert H; Guo, Xiaoqing

Development of a TK6-derived cell line expressing four human cytochrome P450s for genotoxicity testing.

开发表达四种人类细胞色素 P450 的 TK6 衍生细胞系,用于基因毒性测试

Li Xilin, Wang Yuhan, Xu Hannah, He Xiaobo, Chen Si, Guo Xiaoqing, Manjanatha Mugimane G, Zhou Tong, Bonzo Jessica, Mei Nan

Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen.

人类 HepaRG 细胞长期暴露于基因毒性致癌物后发生突变积累

Guo Xiaoqing, Seo Ji-Eun, Miranda-Colon Jaime, Xu Hannah, Revollo Javier, Heflich Robert H

Ocular toxicities associated with MEK/BRAF inhibitors: assessing the accuracy and completeness of large language models

MEK/BRAF抑制剂相关的眼部毒性:评估大型语言模型的准确性和完整性

Kirupaharan, Nila; Edalat, Camellia; Dalvin, Lauren A; Mishra, Kapil; Marshall, Rayna; Xu, Hannah; Francis, Jasmine H; Berkenstock, Meghan

Olfactory receptors as tumor suppressors in cutaneous T-cell lymphoma via p38γ pathway modulation

嗅觉受体通过调节p38γ通路在皮肤T细胞淋巴瘤中发挥抑癌作用

Zhang, Xu Hannah; Li, Hongzhi; Hsiang, Jack; Chen, Chih-Hong; Nam, Sangkil; Wong, Henry; Wu, Xiwei; Hu, Weidong; Shively, Jack; Rosen, Steven T

MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice

在小鼠中,MDM2通过整合iNOS-一氧化氮和HIF-1α通路,诱导M1巨噬细胞产生促炎和糖酵解反应。

Kelvin Ka-Lok Wu ,Xiaofan Xu ,Manyin Wu ,Xiaomu Li ,Moinul Hoque ,Gloria Hoi Yee Li ,Qizhou Lian ,Kekao Long ,Tongxi Zhou ,Hailong Piao ,Aimin Xu ,Hannah Xiaoyan Hui ,Kenneth King-Yip Cheng