Xu Haodong相关文献与解析，生知库 | 链接生命科学的每一步

Synergistic Neurotoxicity of environmental Cadmium and Paraquat in Parkinsonism: Unveiling the Mito-ROS/OPA1/Caspase-3/GSDME-driven Apoptosis Axis.

环境镉和百草枯对帕金森病的协同神经毒性：揭示线粒体ROS/OPA1/Caspase-3/GSDME驱动的细胞凋亡轴。

期刊:International Journal of Biological Sciences

Luo Yufei, Lu Yingying, Tang Yancheng, Zhao Xuejun, Wang Junpu, Liu Yifan, Jiang Sijia, Zhu Yuyuan, Qi Jiaqi, Xing Linlin, Yan Chenghao, Liu Xu, Huang Cainian, Wang Haiji, Xu Haodong, Wang Liming

The emerging role of aptamers in targeted cancer immunotherapy

适体在靶向癌症免疫治疗中的新兴作用

期刊:Molecular Therapy Oncology

影响因子:5.3

doi:10.1016/j.omton.2025.201110

Zhu, Sai; Xu, Ruiling; Xu, Haodong; Wang, Yu; Wang, Lu; He, Na; Wang, Hong-Hui; Ren, Xiaolei

SRSF7 serves as a potential therapeutic target in acute myeloid leukemia

SRSF7是急性髓系白血病潜在的治疗靶点。

期刊:Genes and Diseases

影响因子:

doi:10.1016/j.gendis.2025.101739

Shang, Dantong; Zhu, Hongkai; Pu, Yulin; Liang, Long; Xu, Haodong; Sheng, Yue; Zhang, Huifang

白血病

发表日期：2026

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PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.

PKMYT1激酶可改善骨肉瘤对顺铂的敏感性

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-025-02250-7

Liu Binfeng, Li Wei, Zhang Wenchao, Feng Chengyao, Wan Lu, He Shasha, Xu Ruiling, Fu Zheng, Liu Zhongyue, Xu Haodong, Jin Xin, Tu Chao, Li Zhihong

Necroptosis in cancer: insight from epigenetic, post-transcriptional and post-translational modifications

癌症中的坏死性凋亡：来自表观遗传、转录后和翻译后修饰的启示

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-025-01726-x

Tang, Jinxin; Zhuang, Yan; Zhang, Yibo; Hu, Hongkun; Wang, Hua; Xu, Haodong; Li, Yintao; Tu, Chao

Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis.

抑制 PINK1 可感知 ROS 信号，从而促进神经母细胞瘤细胞焦亡

期刊:Autophagy

影响因子:14.3

doi:10.1080/15548627.2025.2487037

Zhu Yuyuan, Cao Min, Tang Yancheng, Liu Yifan, Wang Haiji, Qi Jiaqi, Huang Cainian, Yan Chenghao, Liu Xu, Jiang Sijia, Luo Yufei, Wang Shaogui, Zhou Bo, Xu Haodong, Lu Ying-Ying, Wang Liming

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma.

采用类器官和 CRISPR 筛选的双重方法揭示 ERCC6 是骨肉瘤顺铂耐药性的决定因素

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202500632

Xu Ruiling, Zhu Sai, Zhang Wenchao, Xu Haodong, Tu Chao, Wang Honghui, Wang Lu, He Na, Liu Tang, Guo Xiaoning, Ren Xiaolei, Li Zhihong

Dr. Kinase: predicting the drug-resistance hotspots of protein kinases

激酶博士：预测蛋白激酶的耐药热点

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf366

Lin, Shaofeng; Tu, Chao; Hu, Ruifeng; Wang, Haiji; Dong, Zongcheng; Luo, Hui; Kuang, Lan; Wang, Tao; Wang, Liming; Zhao, Zhongming; Li, Zhihong; Xu, Haodong

信号转导

发表日期：2025

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Deep learning models in classifying primary bone tumors and bone infections based on radiographs

基于X光片的原发性骨肿瘤和骨感染分类的深度学习模型

期刊:npj Precision Oncology

影响因子:8

doi:10.1038/s41698-025-00855-3

Wang, Hua; He, Yu; Wan, Lu; Li, Chenbei; Li, Zhaoqi; Li, Zhihong; Xu, Haodong; Tu, Chao

Assessment of computational methods in predicting TCR-epitope binding recognition

评估计算方法在预测TCR表位结合识别中的应用

Synergistic Neurotoxicity of environmental Cadmium and Paraquat in Parkinsonism: Unveiling the Mito-ROS/OPA1/Caspase-3/GSDME-driven Apoptosis Axis.

环境镉和百草枯对帕金森病的协同神经毒性：揭示线粒体ROS/OPA1/Caspase-3/GSDME驱动的细胞凋亡轴。

The emerging role of aptamers in targeted cancer immunotherapy

适体在靶向癌症免疫治疗中的新兴作用

SRSF7 serves as a potential therapeutic target in acute myeloid leukemia

SRSF7是急性髓系白血病潜在的治疗靶点。

PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.

PKMYT1激酶可改善骨肉瘤对顺铂的敏感性

Necroptosis in cancer: insight from epigenetic, post-transcriptional and post-translational modifications

癌症中的坏死性凋亡：来自表观遗传、转录后和翻译后修饰的启示

Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis.

抑制 PINK1 可感知 ROS 信号，从而促进神经母细胞瘤细胞焦亡

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma.

采用类器官和 CRISPR 筛选的双重方法揭示 ERCC6 是骨肉瘤顺铂耐药性的决定因素

Dr. Kinase: predicting the drug-resistance hotspots of protein kinases

激酶博士：预测蛋白激酶的耐药热点

Deep learning models in classifying primary bone tumors and bone infections based on radiographs

基于X光片的原发性骨肿瘤和骨感染分类的深度学习模型