文献库，生知库 | 链接生命科学的每一步

日期影响因子

Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite.

脯氨酸脱氢酶是一种限速分解代谢酶，它通过调节弓形虫速殖子的脯氨酸代谢和线粒体功能，影响弓形虫速殖子的生长和致病性

期刊:Parasites & Vectors

影响因子:3.5

doi:10.1186/s13071-025-06966-x

Geng Xiao-Ling, Li Jing-Yu, Xu Huan-Yu, Wu Jiang-Ping, Tao De-Liang, Chen Jin-Ming, Fan Ying-Ying, Yang Xin, Song Jun-Ke, Zhao Guang-Hui

发表日期：2025

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Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities

2,4-二氨基嘧啶衍生物的设计、合成及生物学评价作为具有抗癌和抗血管生成活性的强效 FAK 抑制剂

期刊:European Journal of Medicinal Chemistry

doi:10.1016/j.ejmech.2021.113573

Shan Wang, Rong-Hong Zhang, Hong Zhang, Yu-Chan Wang, Dan Yang, Yong-Long Zhao, Guo-Yi Yan, Guo-Bo Xu, Huan-Yu Guan, Yan-Hua Zhou, Dong-Bing Cui, Ting Liu, Yong-Jun Li, Shang-Gao Liao, Meng Zhou

发表日期：2021

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Genetic and Epigenetic Targeting Therapy for Pediatric Acute Lymphoblastic Leukemia

儿童急性淋巴细胞白血病的基因和表观遗传靶向治疗

影响因子:5.2

doi:10.3390/cells10123349

Xu, Huan; Yu, Hui; Jin, Runming; Wu, Xiaoyan; Chen, Hongbo

细胞生物学

发表日期：2021

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Multiomics analyses unveil the involvement of microRNAs in pear fruit senescence under high- or low-temperature conditions

多组学分析揭示了microRNA在高温或低温条件下梨果实衰老中的作用

doi:10.1038/s41438-020-00420-y

Gu, Chao; Xu, Huan-Yu; Zhou, Yu-Hang; Yao, Jia-Long; Xie, Zhi-Hua; Chen, Yang-Yang; Zhang, Shao-Ling

发表日期：2020

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Effects of leukemia inhibitory factor receptor on the adipogenic differentiation of human bone marrow mesenchymal stem cells

白血病抑制因子受体对人骨髓间充质干细胞脂肪生成分化的影响

期刊:Molecular Medicine Reports

影响因子:3.4

doi:10.3892/mmr.2019.10140

Tao Wang ，Ruiqiao Yan ，Xiaoyuan Xu ，Huan Yu ，Jianfang Wu ，Yaofang Yang ，Weidong Li

发育与干细胞

细胞生物学

发表日期：2019

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Potential Mutations in Uveal Melanoma Identified Using Targeted Next-Generation Sequencing

利用靶向下一代测序技术识别葡萄膜黑色素瘤的潜在突变

期刊:Journal of Cancer

影响因子:3.3

doi:10.7150/jca.26967

Jiayi Yu, Xiaowen Wu, Junya Yan, Jinyu Yu, Ting Yin, Jie Dai, Meng Ma, Tianxiao Xu, Huan Yu, Longwen Xu, Lu Yang, Zhiyuan Cheng, Zhihong Chi, Xinan Sheng, Lu Si, Chuanliang Cui, Jun Guo, Yan Kong

发表日期：2019

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PI3K/AKT/mTOR pathway inhibitors inhibit the growth of melanoma cells with mTOR H2189Y mutations in vitro

PI3K/AKT/mTOR 通路抑制剂体外抑制 mTOR H2189Y 突变黑色素瘤细胞的生长

期刊:Cancer Biology & Therapy

影响因子:4.4

doi:10.1080/15384047.2018.1435221

Xiaowen Wu, Jiayi Yu, Junya Yan, Jie Dai, Lu Si, Zhihong Chi, Xinan Sheng, Chuanliang Cui, Meng Ma, Huan Tang, Tianxiao Xu, Huan Yu, Yan Kong, Jun Guo

发表日期：2018

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Increased AURKA Gene Copy Number Correlates with Poor Prognosis and Predicts the Efficacy of High-dose Interferon Therapy in Acral Melanoma

AURKA 基因拷贝数增加与不良预后相关并可预测肢端黑色素瘤高剂量干扰素治疗的疗效

期刊:Journal of Cancer

影响因子:3.3

doi:10.7150/jca.24013

Junya Yan, Jiayi Yu, Xiaowen Wu, Tianxiao Xu, Huan Yu, Jie Dai, Meng Ma, Huan Tang, Longwen Xu, Zhihong Chi, Lu Si, Xinan Sheng, Chuanliang Cui, Yan Kong, Jun Guo

发表日期：2018

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