Modulation of senescent Lepr(+) skeletal stem cells via suppression of leptin-induced STAT3âFGF7 axis activation alleviates abnormal subchondral bone remodeling and osteoarthritis progression.
通过抑制瘦素诱导的 STAT3-FGF7 轴激活来调节衰老的 Lepr(+) 骨骼干细胞，可减轻异常的软骨下骨重塑和骨关节炎的进展
期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04342-1
Yu Fu-Hao, Yin Bo-Feng, Liu Ming-Yu, Zhang Wen-Jing, Zhao Zhi-Dong, Wang Lei, Li Xiao-Tong, Li Pei-Lin, Li Zhi-Ling, Xu Run-Xiang, Ding Li, Zhu Heng
