日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity

泛素特异性蛋白酶 7 抑制剂揭示 p53 驱动抗癌活性的差异化机制

Alan S Futran, Tao Lu, Katherine Amberg-Johnson, Jiayi Xu, Xiaoxiao Yang, Saidi He, Sarah Boyce, Jeffrey A Bell, Robert Pelletier, Takao Suzuki, Xianhai Huang, Heng Qian, Liping Fang, Li Xing, Zhaowu Xu, Stephen E Kurtz, Jeffrey W Tyner, Wayne Tang, Tao Guo, Karen Akinsanya, David Madge, Kristian K

Triptolide Reduces Neoplastic Progression in Hepatocellular Carcinoma by Downregulating the Lipid Lipase Signaling Pathway

雷公藤甲素通过下调脂质脂肪酶信号通路减缓肝细胞癌的肿瘤进展

Wei Chang, Jingjing Wang, Yuanqi You, Hongqian Wang, Shendong Xu, Stephen Vulcano, Changlu Xu, Chenlin Shen, Zhi Li, Jie Wang

Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis

肿瘤分泌的外泌体 miR-141 激活肿瘤-基质相互作用并控制卵巢癌转移中的转移前微环境形成

Yulan Mo, Leanne L Leung, Celia S L Mak, Xueyu Wang, Wai-Sun Chan, Lynn M N Hui, Hermit W M Tang, Michelle K Y Siu, Rakesh Sharma, Dakang Xu, Stephen K W Tsui, Hextan Y S Ngan, Mingo M H Yung, Karen K L Chan, David W Chan

CIS controls the functional polarization of GM-CSF-derived macrophages

CIS 控制 GM-CSF 衍生巨噬细胞的功能极化

Shengbo Zhang #, Jai Rautela #, Naiara G Bediaga #, Tatiana B Kolesnik #, Yue You, Junli Nie, Laura F Dagley, Justin Bedo, Hanqing Wang, Li Sun, Robyn Sutherland, Elliot Surgenor, Nadia Iannarella, Rhys Allan, Fernando Souza-Fonseca-Guimaraes, Yi Xie, Qike Wang, Yuxia Zhang, Yuekang Xu, Stephen L Nu

Guselkumab provides sustained domain-specific and comprehensive efficacy using composite indices in patients with active psoriatic arthritis

古塞库单抗在活动性银屑病关节炎患者中通过综合指标显示出持续的、特定领域的和全面的疗效

Coates, Laura C; Ritchlin, Christopher T; Gossec, Laure; Helliwell, Philip S; Rahman, Proton; Kollmeier, Alexa P; Xu, Xie L; Shawi, May; Karyekar, Chetan S; Contré, Christine; Noël, Wim; Sheng, Shihong; Wang, Yanli; Xu, Stephen; Mease, Philip J

Estradiol Augments Tumor-Induced Neutrophil Production to Promote Tumor Cell Actions in Lymphangioleiomyomatosis Models

雌二醇增强肿瘤诱导的中性粒细胞生成,从而促进淋巴管肌瘤病模型中的肿瘤细胞活性

Briaunna M N Minor ,Dana LeMoine ,Christina Seger ,Erin Gibbons ,Jules Koudouovoh ,Manisha Taya ,Daniel Kurtz ,Yan Xu ,Stephen R Hammes

Methyltransferase Inhibition Enables Tgf β Driven Induction of CDKN2A and B in Cancer Cells

甲基转移酶抑制可使 Tgf β 驱动癌细胞中 CDKN2A 和 B 的诱导

Yen-Ting Liu, Celeste Romero, Xue Xiao, Lei Guo, Xiaoyun Zhou, Mark A Applebaum, Lin Xu, Stephen X Skapek

Response to Treatment with Intravenous Golimumab or Infliximab in Rheumatoid Arthritis Patients: PROMIS Results from the Real-World Observational Phase 4 AWARE Study

类风湿性关节炎患者接受静脉注射戈利木单抗或英夫利昔单抗治疗的反应:来自真实世界观察性 4 期 AWARE 研究的 PROMIS 结果

Bingham, Clifton O 3rd; Black, Shawn; Shiff, Natalie J; Xu, Stephen; Langholff, Wayne; Curtis, Jeffrey R

Effect of Intravenous Golimumab on Fatigue and the Relationship with Clinical Response in Adults with Active Ankylosing Spondylitis in the Phase 3 GO-ALIVE Study

在 GO-ALIVE 3 期研究中,静脉注射戈利木单抗对活动性强直性脊柱炎成人患者疲劳的影响及其与临床反应的关系

Deodhar, Atul; Shiff, Natalie J; Gong, Cinty; Chan, Eric K H; Hsia, Elizabeth C; Lo, Kim Hung; Akawung, Alianu; Kim, Lilianne; Xu, Stephen; Reveille, John D

Efficacy of Guselkumab on Axial-Related Symptoms Through up to 2 Years in Adults with Active Psoriatic Arthritis in the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Study

在3期随机、安慰剂对照的DISCOVER-2研究中,古塞库单抗对活动性银屑病关节炎成人患者的轴向相关症状的疗效长达2年

Mease, Philip J; Gladman, Dafna D; Poddubnyy, Denis; Chakravarty, Soumya D; Shawi, May; Kollmeier, Alexa P; Xu, Xie L; Xu, Stephen; Deodhar, Atul; Baraliakos, Xenofon