日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dual indexed library design enables compatibility of in-Drop single-cell RNA-sequencing with exAMP chemistry sequencing platforms.

双索引文库设计实现了液滴内单细胞 RNA 测序与 exAMP 化学测序平台的兼容性

Southard-Smith Austin N, Simmons Alan J, Chen Bob, Jones Angela L, Ramirez Solano Marisol A, Vega Paige N, Scurrah Cherie' R, Zhao Yue, Brenan Michael J, Xuan Jiekun, Shrubsole Martha J, Porter Ely B, Chen Xi, Brenan Colin J H, Liu Qi, Quigley Lauren N M, Lau Ken S

A functional SNP in the 3'-UTR of TAP2 gene interacts with microRNA hsa-miR-1270 to suppress the gene expression

TAP2基因3'-UTR中的一个功能性SNP与microRNA hsa-miR-1270相互作用,从而抑制基因表达。

Knox, Bridgett; Wang, Yong; Rogers, Lora J; Xuan, Jiekun; Yu, Dianke; Guan, Huaijin; Chen, Jiwei; Shi, Tieliu; Ning, Baitang; Kadlubar, Susan A

Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells

内质网应激和MAPK信号通路激活是来氟米特诱导HepG2细胞毒性的基础。

Ren, Zhen; Chen, Si; Qing, Tao; Xuan, Jiekun; Couch, Letha; Yu, Dianke; Ning, Baitang; Shi, Leming; Guo, Lei

Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity

开发表达细胞色素P450的HepG2衍生细胞用于评估代谢相关的药物引起的肝毒性

Xuan, Jiekun; Chen, Si; Ning, Baitang; Tolleson, William H; Guo, Lei

The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity

CYP 3A4 和 1A1 在胺碘酮诱导的肝细胞毒性中的作用

Wu, Qiangen; Ning, Baitang; Xuan, Jiekun; Ren, Zhen; Guo, Lei; Bryant, Matthew S

Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells

银杏叶提取物通过抑制人肝细胞中拓扑异构酶II的活性诱导DNA损伤

Zhang, Zhuhong; Chen, Si; Mei, Hu; Xuan, Jiekun; Guo, Xiaoqing; Couch, Letha; Dobrovolsky, Vasily N; Guo, Lei; Mei, Nan

Sertraline induces endoplasmic reticulum stress in hepatic cells

舍曲林可诱导肝细胞内质网应激

Chen, Si; Xuan, Jiekun; Couch, Letha; Iyer, Advait; Wu, Yuanfeng; Li, Quan-Zhen; Guo, Lei

Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway

抗抑郁药舍曲林可通过丝裂原活化蛋白激酶通路诱导肝细胞凋亡。

Chen, Si; Xuan, Jiekun; Wan, Liqing; Lin, Haixia; Couch, Letha; Mei, Nan; Dobrovolsky, Vasily N; Guo, Lei

Next-generation sequencing in the clinic: promises and challenges

下一代测序技术在临床中的应用:前景与挑战

Xuan, Jiekun; Yu, Ying; Qing, Tao; Guo, Lei; Shi, Leming