日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Use of LC-MS to characterize host cell protein removal during depth filtration

利用液相色谱-质谱联用技术表征深度过滤过程中宿主细胞蛋白的去除情况

Chu, Liang-Kai; Borujeni, Ehsan Espah; Xu, Xuankuo; Zydney, Andrew L

Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography

富含宿主细胞蛋白质的聚集体在抗体捕获和精制层析中的行为

Chase E Herman, Lie Min, Leila H Choe, Ronald W Maurer, Xuankuo Xu, Sanchayita Ghose, Kelvin H Lee, Abraham M Lenhoff

Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody

收获物深层过滤在控制双特异性抗体产品相关杂质中的作用

Ehsan Espah Borujeni, Weixin Jin, Chun Shao, Naresh Chennamsetty, Xuankuo Xu, Sanchayita Ghose

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics

设计具有改进的可制造性和生物分析特性的下一代治疗性 IgG4

Zhiqiang Chen, Yueming Qian, Yuanli Song, Xuankuo Xu, Li Tao, Nesredin Mussa, Sanchayita Ghose, Zheng Jian Li

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media

通过优化低铁化学成分培养基中的 CHO 细胞培养条件来提高滴度,同时保持最终配制药物的质量

Jianlin Xu, Matthew S Rehmann, Xuankuo Xu, Chao Huang, Jun Tian, Nan-Xin Qian, Zheng Jian Li

Mechanisms of precipitate formation during the purification of an Fc-fusion protein

Fc融合蛋白纯化过程中沉淀形成的机制

Greene, Daniel G; Traylor, Steven J; Guo, Jing; Choe, Leila H; Modla, Shannon; Xu, Xuankuo; Singh, Nripen; Lock, Lye Lin; Ghose, Sanchayita; Li, Zheng Jian; Lee, Kelvin H; Wagner, Norman J; Lenhoff, Abraham M

Chromatography of proteins on charge-variant ion exchangers and implications for optimizing protein uptake rates

电荷变体离子交换器上的蛋白质色谱分析及其对优化蛋白质吸收率的影响

John F Langford Jr, Xuankuo Xu, Yan Yao, Sean F Maloney, Abraham M Lenhoff