Yan Haiyan相关文献与解析，生知库 | 链接生命科学的每一步

Aptamers targeting respiratory syncytial virus showed high inhibitory activity by blocking the G protein

靶向呼吸道合胞病毒的适体通过阻断G蛋白表现出很高的抑制活性。

doi:10.1016/j.apsb.2025.12.027

Yang, Ge; Jiang, Guangyu; Lian, Xintao; Cui, Boming; Wu, Shuo; Wang, Huiqiang; Yan, Haiyan; Wang, Kun; Gao, Rongmei; Qu, Feng; Jiang, Jiandong; Li, Yuhuan

Analysis of risk factors and establishment of a prediction model for latent autoimmune diabetes in adults

成人隐匿性自身免疫性糖尿病风险因素分析及预测模型建立

期刊:Therapeutic Advances in Endocrinology and Metabolism

影响因子:4.6

doi:10.1177/20420188261423784

Yan, Haiyan; Lv, Jiarong; Miao, Lingling; Shi, Lei

ggplotAgent: a self-debugging multi-modal agent for robust and reproducible scientific visualization

ggplotAgent：一个用于实现稳健且可复现的科学可视化的自调试多模态代理

期刊:Bioinformatics Advances

影响因子:2.8

doi:10.1093/bioadv/vbaf332

Wang, Zelin; Yin, Yuanyuan; Wang, Jien; Yan, Haiyan; Xie, Xuan; Zheng, Yiqing

发表日期：2026

文献求助收藏

The cAMP-PKA signaling initiates mitosis by phosphorylating Bora.

cAMP-PKA信号通路通过磷酸化Bora蛋白启动有丝分裂

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-63352-y

Zhu Min, Zhou Shinan, Zhang Yingqi, Chen Qinfu, Yuan Xueying, Zhang Long, Yan Haiyan, Wang Fangwei

Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

Ce6衍生物光动力疗法通过阻断LAG3诱导PANoptosis并增强皮肤鳞状细胞癌的抗肿瘤免疫力

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2025.102239

Diyan Chen ，Bo Wang ，Chunying Li ，Hui Tao ，Fangqi Lu ，Zhijie Ruan ，Zijun Zhao ，Chunxiao Li ，Guorong Yan ，Haiyan Zhang ，Yeqiang Liu ，Xiuli Wang ，Guolong Zhang ，Qingyu Zeng

Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy

阐明N-肉豆蔻酰化在缺氧肿瘤中PD-L1过度膜定位中的作用，并开发一种新型NMT1抑制剂，用于与免疫检查点阻断疗法联合治疗。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:11.4

doi:10.1186/s13046-025-03438-z

Haoming Zhao ，Zhen Zhang ，Chaojun Zhang ，Hexin Ma ，Qingqing Wan ，Xinran Zhao ，Xu Wang ，Ming Yan ，Haiyan Guo ，Jianjun Zhang ，Wantao Chen

Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan-Coronavirus Inhibitor

干扰病毒入侵过程中刺突蛋白的启动：四氢帕马汀作为一种泛冠状病毒抑制剂

期刊:MedComm

影响因子:10.7

doi:10.1002/mco2.70353

Wang, Kun; Wang, Huiqiang; Wu, Shuo; Yang, Ge; Yan, Haiyan; Qiao, Lijun; Li, Xingqiong; Wu, Mengyuan; Jiang, Jiandong; Li, Yuhuan

微生物学

发表日期：2025

文献求助收藏

A chromatin-remodeling-independent role for ATRX in protecting centromeric cohesion.

ATRX 在保护着丝粒凝聚力方面发挥着不依赖于染色质重塑的作用

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/s44318-025-00465-6

Zhao Lei, Yuan Xueying, Chen Qinfu, Yan Haiyan, Wang Fangwei

其它

发表日期：2025

文献求助收藏

Comprehensive dataset of interactors for the entire PARP family using TurboID proximity labeling.

利用 TurboID 邻近标记法构建了整个 PARP 家族的互作蛋白综合数据集

期刊:Scientific Data

影响因子:6.9

doi:10.1038/s41597-025-04722-5

Zheng Jiefu, Deng Yawen, Fang Cong, Xiong Shiyu, Zhu Xudong, Wu Weijun, Chen Xinliang, Wu Wenjing, Yin Dong, Hu Kaishun, Yan Haiyan

免疫/内分泌

发表日期：2025

文献求助收藏

Sororin locks the DNA-exit gate of cohesin to preserve sister-chromatid cohesion.

索罗林锁定黏连蛋白的 DNA 出口，以维持姐妹染色单体的黏连。

Aptamers targeting respiratory syncytial virus showed high inhibitory activity by blocking the G protein

靶向呼吸道合胞病毒的适体通过阻断G蛋白表现出很高的抑制活性。

Analysis of risk factors and establishment of a prediction model for latent autoimmune diabetes in adults

成人隐匿性自身免疫性糖尿病风险因素分析及预测模型建立

ggplotAgent: a self-debugging multi-modal agent for robust and reproducible scientific visualization

ggplotAgent：一个用于实现稳健且可复现的科学可视化的自调试多模态代理

The cAMP-PKA signaling initiates mitosis by phosphorylating Bora.

cAMP-PKA信号通路通过磷酸化Bora蛋白启动有丝分裂

Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

Ce6衍生物光动力疗法通过阻断LAG3诱导PANoptosis并增强皮肤鳞状细胞癌的抗肿瘤免疫力

Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy

阐明N-肉豆蔻酰化在缺氧肿瘤中PD-L1过度膜定位中的作用，并开发一种新型NMT1抑制剂，用于与免疫检查点阻断疗法联合治疗。

Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan-Coronavirus Inhibitor

干扰病毒入侵过程中刺突蛋白的启动：四氢帕马汀作为一种泛冠状病毒抑制剂

A chromatin-remodeling-independent role for ATRX in protecting centromeric cohesion.

ATRX 在保护着丝粒凝聚力方面发挥着不依赖于染色质重塑的作用

Comprehensive dataset of interactors for the entire PARP family using TurboID proximity labeling.

利用 TurboID 邻近标记法构建了整个 PARP 家族的互作蛋白综合数据集