日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2.

利用 nanoPDLIM2 改善 PD-1 阻断联合化疗治疗肺癌的疗效,实现肺癌完全缓解

Sun Fan, Yan Pengrong, Xiao Yadong, Zhang Hongqiao, Shapiro Steven D, Xiao Gutian, Qu Zhaoxia

Neutrophil extracellular trap related risk score exhibits crucial prognostic value in skin cutaneous melanoma, associating with distinct immune characteristics

中性粒细胞胞外陷阱相关风险评分在皮肤黑色素瘤的预后中具有重要的预测价值,并与独特的免疫特征相关。

Zhang, Haiyang; Bi, Xiaoqing; Yan, Pengrong; Wang, Congcong

Disease-specific interactome alterations via epichaperomics: the case for Alzheimer's disease

通过表观分子伴侣组学揭示疾病特异性相互作用组的改变:以阿尔茨海默病为例

Ginsberg, Stephen D; Neubert, Thomas A; Sharma, Sahil; Digwal, Chander S; Yan, Pengrong; Timbus, Calin; Wang, Tai; Chiosis, Gabriela

A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond

癌症分子伴侣的化学生物学研究——HSP90及其他

Taldone, Tony; Wang, Tai; Rodina, Anna; Pillarsetty, Naga Vara Kishore; Digwal, Chander S; Sharma, Sahil; Yan, Pengrong; Joshi, Suhasini; Pagare, Piyusha P; Bolaender, Alexander; Roboz, Gail J; Guzman, Monica L; Chiosis, Gabriela

Chaperome Networks - Redundancy and Implications for Cancer Treatment

分子伴侣网络——冗余性及其对癌症治疗的影响

Yan, Pengrong; Wang, Tai; Guzman, Monica L; Peter, Radu I; Chiosis, Gabriela

Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

PDLIM2表观遗传抑制在肺癌和治疗耐药性中的致病作用

Sun, Fan; Li, Liwen; Yan, Pengrong; Zhou, Jingjiao; Shapiro, Steven D; Xiao, Gutian; Qu, Zhaoxia

Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein

人 HSP70 蛋白上变构口袋的鉴定揭示了一种抑制这种具有重要治疗价值的蛋白质的机制。

Rodina, Anna; Patel, Pallav D; Kang, Yanlong; Patel, Yogita; Baaklini, Imad; Wong, Michael J H; Taldone, Tony; Yan, Pengrong; Yang, Chenghua; Maharaj, Ronnie; Gozman, Alexander; Patel, Maulik R; Patel, Hardik J; Chirico, William; Erdjument-Bromage, Hediye; Talele, Tanaji T; Young, Jason C; Chiosis, Gabriela

DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target

结肠癌中 PDZ-LIM 结构域蛋白 2 的 DNA 甲基化依赖性抑制及其作为潜在治疗靶点的作用

Qu, Zhaoxia; Yan, Pengrong; Fu, Jing; Jiang, Jing; Grusby, Michael J; Smithgall, Thomas E; Xiao, Gutian

Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer

PDZ-LIM结构域蛋白2的表观遗传抑制:对乳腺癌生物学和治疗的意义

Qu, Zhaoxia; Fu, Jing; Yan, Pengrong; Hu, Jing; Cheng, Shi-Yuan; Xiao, Gutian

Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax.

人类 T 细胞白血病病毒 I 型介导的 PDZ-LIM 结构域蛋白 2 的抑制涉及 DNA 甲基化,但与病毒癌蛋白 tax 无关

Yan Pengrong, Qu Zhaoxia, Ishikawa Chie, Mori Naoki, Xiao Gutian