Yan Yao相关文献与解析，生知库 | 链接生命科学的每一步

A single-dose of PDGFB circular RNA enables sustained growth factor expression to accelerate diabetic wound healing.

单剂量 PDGFB 环状 RNA 可实现持续的生长因子表达，从而加速糖尿病伤口愈合。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04106-w

Shen Yi-Qi, Zhang Yan, Yao Liu-Yi, Zhang Ru-Ke, Yang Bin, Deng Cheng-Cheng

Circulating Microbial Metabolites Predict Tumor Relapse and Chemotherapy Efficacy in Nasopharyngeal Carcinoma

循环微生物代谢产物可预测鼻咽癌的肿瘤复发和化疗疗效

期刊:MedComm

影响因子:10.7

doi:10.1002/mco2.70687

Li, Jun-Yan; Yao, Yao; Tan, Xi-Rong; Si, Nan; Jiang, Wei; Lu, Ying-Qi; Dai, Jia-Hao; Yu, Tian-Tian; Hu, Hao-Cheng; Duan, Yu-Fei; Feng, Sen-Yu; Huang, Sai-Wei; Liang, Ye-Lin; Gong, Sha; Liu, Na; Hu, Yu-Min; Li, Ying-Qing

Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma

基于SIGLEC9的合成嵌合开关受体增强CAR巨噬细胞对胶质母细胞瘤的疗效

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2519819123

Fu, Zhipeng; Zhao, Xiaotian; Zhang, Qikang; Han, Maosen; Zhang, Jing; Yang, Zhenmei; Wang, Yan; Yao, Zichao; Liu, Ying; Tang, Chunwei; Xi, Kaiyan; Liu, Zhanyan; Zhang, Yi; Zhao, Kun; Li, Na; Zhang, Yulin; Song, Yudong; Jiang, Xinyi; Chen, Chen

The novel IDO-1 inhibitor 3-047 combined with icaritin ameliorates neuroinflammation and diabetes-associated cognitive dysfunction with suppression of TLR4/MyD88/NF-ÎºB signaling.

新型 IDO-1 抑制剂 3-047 与淫羊藿苷联合使用，可通过抑制 TLR4/MyD88/NF-κB 信号传导来改善神经炎症和糖尿病相关的认知功能障碍。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1704307

Mo Tingmei, Zhuang Xia, Zhao Wenxue, Wang Baohua, Wang Yuting, Ji Wenjie, Liu Dongguang, Zhang Guimin, Yao Ru, Xu Yan, Yao Jingchun

Immunology/Inflammation

炎症

发表日期：2026

文献求助收藏

Protective Effects of Licochalcone A Against Alcoholic Liver Injury in Mice by Modulating the Gut-Liver Axis and TLR4/NF-κB Pathway

甘草查尔酮A通过调节肠-肝轴和TLR4/NF-κB通路对小鼠酒精性肝损伤的保护作用

期刊:Foods

影响因子:5.1

doi:10.3390/foods15050915

Yuan, Yue; Li, Chenyang; Toliken, Aididar; Chen, Yan; Yao, Yuhan; Zhao, Jun

NF-κB

发表日期：2026

文献求助收藏

Enhancing the breadth of protection in mice with a multivalent influenza vaccine

利用多价流感疫苗增强小鼠的保护范围

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-09451-4

Wang, Xiang; Niu, Yixin; Hu, Ying; Zhu, Caihong; Yang, Xi; Shi, Hongyang; Yan, Yao; Zhou, Ping; Ding, Longfei; Zhang, Miaomiao; Wu, Mangteng; Tang, Shubing; Xing, Man; Zhou, Dongming

Single cell snapshot analyses under proper representation reveal that epithelial-mesenchymal transition couples at G1 and G2/M

在适当的表征条件下进行的单细胞快照分析表明，上皮-间质转化在 G1 期和 G2/M 期偶联。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-09487-6

Hu, Sophia; Lu, Yong; Yu, Gaohan; Zheng, Zhiqian; Ni, Ke; Giri, Amitava; Zhang, Jingyu; Zhang, Yan; Yao, Guang; Xing, Jianhua

Multiple-element exposure in early pregnancy and birth defects: a nested case-control study based on the China birth cohort study

早期妊娠多因素暴露与出生缺陷：一项基于中国出生队列研究的嵌套病例对照研究

期刊:Frontiers in Nutrition

影响因子:5.1

doi:10.3389/fnut.2026.1722672

Zhang, Weichunbai; Zhang, Jianming; Du, Jing; Ma, Qinglin; Shan, Tianhao; Sun, Shanshan; Yang, Yunjia; Li, Hong; Li, Gang; Song, Yan; Yao, Jilong; Yang, Yi

发表日期：2026

文献求助收藏

Tryptophan catabolism reprograms immunity to prevent hemolymph bacterial dysbiosis and support molting in Spätzle-deficient Helicoverpa armigera larvae

色氨酸分解代谢重编程免疫系统，以防止血淋巴细菌失调并支持缺乏 Spätzle 的棉铃虫幼虫蜕皮。

期刊:BMC Biology

影响因子:4.5

doi:10.1186/s12915-026-02504-y

Xiong, Pei; Luo, Ling-Ling; Kang, Bing-Yan; Yao, Jing-Jing; Liu, Xu-Sheng; Wang, Jia-Lin

AI-Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue

用于微创检测异常肠道组织的AI增强型振动胶囊

A single-dose of PDGFB circular RNA enables sustained growth factor expression to accelerate diabetic wound healing.

单剂量 PDGFB 环状 RNA 可实现持续的生长因子表达，从而加速糖尿病伤口愈合。

Circulating Microbial Metabolites Predict Tumor Relapse and Chemotherapy Efficacy in Nasopharyngeal Carcinoma

循环微生物代谢产物可预测鼻咽癌的肿瘤复发和化疗疗效

Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma

基于SIGLEC9的合成嵌合开关受体增强CAR巨噬细胞对胶质母细胞瘤的疗效

The novel IDO-1 inhibitor 3-047 combined with icaritin ameliorates neuroinflammation and diabetes-associated cognitive dysfunction with suppression of TLR4/MyD88/NF-ÎºB signaling.

新型 IDO-1 抑制剂 3-047 与淫羊藿苷联合使用，可通过抑制 TLR4/MyD88/NF-κB 信号传导来改善神经炎症和糖尿病相关的认知功能障碍。

Protective Effects of Licochalcone A Against Alcoholic Liver Injury in Mice by Modulating the Gut-Liver Axis and TLR4/NF-κB Pathway

甘草查尔酮A通过调节肠-肝轴和TLR4/NF-κB通路对小鼠酒精性肝损伤的保护作用

Enhancing the breadth of protection in mice with a multivalent influenza vaccine

利用多价流感疫苗增强小鼠的保护范围

Single cell snapshot analyses under proper representation reveal that epithelial-mesenchymal transition couples at G1 and G2/M

在适当的表征条件下进行的单细胞快照分析表明，上皮-间质转化在 G1 期和 G2/M 期偶联。

Multiple-element exposure in early pregnancy and birth defects: a nested case-control study based on the China birth cohort study

早期妊娠多因素暴露与出生缺陷：一项基于中国出生队列研究的嵌套病例对照研究

Tryptophan catabolism reprograms immunity to prevent hemolymph bacterial dysbiosis and support molting in Spätzle-deficient Helicoverpa armigera larvae

色氨酸分解代谢重编程免疫系统，以防止血淋巴细菌失调并支持缺乏 Spätzle 的棉铃虫幼虫蜕皮。