Yan Zhiliang相关文献与解析，生知库 | 链接生命科学的每一步

Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-ÎºB pathway.

头孢兰汀通过激活 Nrf2 和抑制 NF-κB 通路来缓解慢性前列腺炎/慢性盆腔疼痛综合征。

Zhang Hang, Zhang Dahong, Wang Ziyi, Liu Kailong, Xu Chao, Sun Hao, Yan Zhiliang, Li Chongbin, Lu Baosai, Yin Yuewei, Zhao Chenming, Niu Yalin, Li Wei

信号转导

发表日期：2026

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Improving lung cancer pathological hyperspectral diagnosis through cell-level annotation refinement

通过细胞水平注释改进提高肺癌病理高光谱诊断水平

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-85678-9

Yan, Zhiliang; Huang, Haosong; Geng, Rongmei; Zhang, Jingang; Chen, Yu; Nie, Yunfeng

Mechanism of NUMBL enhancing axitinib resistance in clear cell renal cell carcinoma by UCHL1-mediated deubiquitination of MMP9.

NUMBL 通过 UCHL1 介导的 MMP9 去泛素化增强透明细胞肾细胞癌对阿昔替尼的耐药性机制。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.110873

Wang Ziyi, Chen Lian, Zhang Hang, Yan Zhiliang, Liu Kailong, Qi Jinchun, Lu Baosai, Yin Yuewei, Zhao Chenming, Niu Yalin, Li Wei

The association between gut microbiota and accelerated aging and frailty: a Mendelian randomization study

肠道菌群与加速衰老和衰弱之间的关联：一项孟德尔随机化研究

期刊:Aging Clinical and Experimental Research

影响因子:3.4

doi:10.1007/s40520-025-02971-3

Yan, Zhiliang; Guan, Guoyu; Jia, Hanqi; Li, Hanyu; Zhuoga, Sangdan; Zheng, Songbai

Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis

内质网应激传感器 IRE1α 的 Ser724 位点的磷酸化可控制其激活状态并限制内质网应激诱导的肝脂肪变性

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2022.101997

Yang Li, Shijia Huang, Jingsi Wang, Jianli Dai, Jie Cai, Shuai Yan, Zhiliang Huang, Shengqi He, Ping Wang, Jianmiao Liu, Yong Liu

Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC

视黄酸受体相关受体 α (Rorα) 的缺失会促进紫外线诱发的 cSCC 进展

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-021-03525-x

Guolong Zhang #, Guorong Yan #, Zhiliang Fu, Yuhao Wu, Fei Wu, Zhe Zheng, Shan Fang, Ying Gao, Xunxia Bao, Yeqiang Liu, Xiuli Wang, Sibo Zhu

信号转导

发表日期：2021

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A Novel Approach for Drug-Target Interactions Prediction Based on Multimodal Deep Autoencoder

一种基于多模态深度自编码器的药物-靶点相互作用预测新方法

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2019.01592

Wang, Huiqing; Wang, Jingjing; Dong, Chunlin; Lian, Yuanyuan; Liu, Dan; Yan, Zhiliang

发表日期：2019

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HMI-LUSC: A Histological Hyperspectral Imaging Dataset for Lung Squamous Cell Carcinoma

HMI-LUSC：肺鳞状细胞癌组织学高光谱成像数据集

Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-ÎºB pathway.

头孢兰汀通过激活 Nrf2 和抑制 NF-κB 通路来缓解慢性前列腺炎/慢性盆腔疼痛综合征。

Improving lung cancer pathological hyperspectral diagnosis through cell-level annotation refinement

通过细胞水平注释改进提高肺癌病理高光谱诊断水平

Mechanism of NUMBL enhancing axitinib resistance in clear cell renal cell carcinoma by UCHL1-mediated deubiquitination of MMP9.

NUMBL 通过 UCHL1 介导的 MMP9 去泛素化增强透明细胞肾细胞癌对阿昔替尼的耐药性机制。

The association between gut microbiota and accelerated aging and frailty: a Mendelian randomization study

肠道菌群与加速衰老和衰弱之间的关联：一项孟德尔随机化研究

Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis

内质网应激传感器 IRE1α 的 Ser724 位点的磷酸化可控制其激活状态并限制内质网应激诱导的肝脂肪变性

Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC

视黄酸受体相关受体 α (Rorα) 的缺失会促进紫外线诱发的 cSCC 进展

A Novel Approach for Drug-Target Interactions Prediction Based on Multimodal Deep Autoencoder

一种基于多模态深度自编码器的药物-靶点相互作用预测新方法