Yan-Yan相关文献与解析，生知库 | 链接生命科学的每一步

Jason E Chan #,Chun-Hao Pan #,Jonathan Rub,Gary Guzman,Klavdija Krause,Emma Brown,Zeda Zhang,Hannah Styers,Griffin Hartmann,Zhuxuan Li,Xueqian Zhuang,Scott W Lowe,Doron Betel,Yan Yan,Tuomas Tammela

肺癌

细胞生物学

肿瘤

发表日期：2026

文献求助收藏

Efficacy and Safety of Neoadjuvant TQB2102 in Locally Advanced or Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: A Randomized, Open-Label, Multicenter, Phase II Trial

新辅助TQB2102治疗局部晚期或早期人表皮生长因子受体2阳性乳腺癌的疗效和安全性：一项随机、开放标签、多中心II期试验

期刊:Journal of Clinical Oncology

影响因子:41.9

doi:10.1200/JCO-25-01153

Li, Jun-Jie; Zhang, Wen-Juan; Zeng, Xiao-Hua; Zhang, Qing-Yuan; Chen, Li; Wu, Jiong; Liu, Guang-Yu; Wang, Zhi-Hong; Hu, Xiao-Bo; Hu, Yan-Yan; Li, Zhen-Ling; Shao, Zhi-Ming

Copper Single-Atoms Loaded on Molybdenum Disulphide Drive Bacterial Cuproptosis-Like Death and Interrupt Drug-Resistance Compensation Pathways

负载于二硫化钼上的铜单原子可诱导细菌发生类似铜凋亡的死亡，并干扰耐药性补偿途径

期刊:Nano-Micro Letters

影响因子:36.3

doi:10.1007/s40820-025-01955-2

Wang, Wenqi; Wei, Xiaolong; Xu, Bolong; Gui, Hengshuo; Yan, Yan; Liu, Huiyu; Wang, Xianwen

Sensing of DNA double-strand breaks by the NHEJ system stabilizes RORγt transcriptional activity and shapes Th17 pathogenicity in autoimmunity

NHEJ系统对DNA双链断裂的感知可稳定RORγt转录活性，并影响Th17在自身免疫中的致病性。

期刊:Cell Research

影响因子:25.9

doi:10.1038/s41422-025-01204-6

Chen, Guan-Yu; Zhu, Wen-Jie; Li, Zhuang; Hu, Yun-Wei; Luo, Xiao-Shuang; Mai, Zhi-Qing; Pan, Yuan; Shi, Yu-Xun; Li, Zuo-Yi; Huang, Jun; Yuan, Pei-Dong; Xiao, Zhi-Qiang; Chen, Qian; Xie, Yan-Yan; Huang, Hai-Xiang; Chen, Yu-Xi; Lu, Yao; Wang, Min-Zhen; Xia, Yi-Wen; Chen, Xiao-Qing; Kuang, Dong-Ming; Liang, Dan

Barrier-disrupting microneedle technology: Overcoming physical, physiological, and pathological skin defenses to enhance therapeutic efficacy

屏障破坏型微针技术：克服皮肤的物理、生理和病理防御机制，提升治疗效果

期刊:Bioactive Materials

影响因子:20.3

doi:10.1016/j.bioactmat.2025.11.005

Jiang, Zeshi; Wu, Wentao; Chen, Tianxiang; Hu, Wanshan; Zhang, Xinyu; Zhou, Chunxian; Lu, Anqi; Yan, Yan; Quan, Guilan; Wu, Chuanbin; Pan, Xin; Cai, Jianfeng; Lu, Chao; Peng, Tingting

发表日期：2026

文献求助收藏

Viral SAM-binding proteins nsp14 and NP868R reprogram ATG4A-dependent autophagy from antiviral LC3B activity to GABARAP-mediated mitophagy.

病毒 SAM 结合蛋白 nsp14 和 NP868R 将 ATG4A 依赖性自噬从抗病毒 LC3B 活性重编程为 GABARAP 介导的线粒体自噬。

期刊:Autophagy

影响因子:14.3

doi:10.1080/15548627.2025.2608972

Li Yahui, Zhu Ya, Wang Fei, Ying Xuezhi, Zhao Chenchen, Si Wei, Zhong Jiepeng, Yin Wei, Lin Lulu, Li Jian, Yan Yan, Zhou Jiyong, Hu Boli

Breaking the activity-stability limit in acidic oxygen evolution reaction with dual-iridium active sites

利用双铱活性位点突破酸性析氧反应的活性-稳定性极限

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.aee7510

Tang, Lei; Tu, Yunchuan; Zhang, Mingyue; Yan, Yan; Xi, Shibo; Liu, Yan; Liu, Yijiang; Pérez-Ramírez, Javier; Lin, Zhiqun

发表日期：2026

文献求助收藏

Tunable Colloidal Synthesis Enabling μ-ARPES on Individual Bismuth Nanocrystals

可调控胶体合成实现对单个铋纳米晶体的μ-ARPES研究

期刊:Small

影响因子:12.1

doi:10.1002/smll.202512032

He, Fagui; Grisan Qiu, Yan Yan; Mearini, Simone; Feyer, Vitaliy; Oldenburg, Kevin; Lesyuk, Rostyslav; Klinke, Christian

信号转导

发表日期：2026

文献求助收藏

Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9(+) macrophages via the mTORC1-C/EBPβ-OSM axis

雷帕霉素通过 mTORC1-C/EBPβ-OSM 轴重编程 Cxcl9(+) 巨噬细胞，从而在自身免疫性心肌炎中维持心脏功能。

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2025.103970

Zhuang, Yan; Yan, Yongcui; Wen, Zheng; Rao, Xiaoquan; Jiang, Jiangang; Li, Huihui; Wang, Dao Wen

The cGAS-STING pathway at the crossroads of neuroimmunology: bridging innate immunity to aging and neurodegeneration

cGAS-STING通路处于神经免疫学的十字路口：连接先天免疫与衰老和神经退行性疾病

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-026-00906-2

Wu, Zheng; Jia, Rong-Jun; Zhang, Qi; Huang, Li-Yan; Yan, Jun-Ting; Zhang, Yan-Hui; Fan, Yong-Gang

Critical role for a high-plasticity cell state in lung cancer

高可塑性细胞状态在肺癌中的关键作用

Efficacy and Safety of Neoadjuvant TQB2102 in Locally Advanced or Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: A Randomized, Open-Label, Multicenter, Phase II Trial

新辅助TQB2102治疗局部晚期或早期人表皮生长因子受体2阳性乳腺癌的疗效和安全性：一项随机、开放标签、多中心II期试验

Copper Single-Atoms Loaded on Molybdenum Disulphide Drive Bacterial Cuproptosis-Like Death and Interrupt Drug-Resistance Compensation Pathways

负载于二硫化钼上的铜单原子可诱导细菌发生类似铜凋亡的死亡，并干扰耐药性补偿途径

Sensing of DNA double-strand breaks by the NHEJ system stabilizes RORγt transcriptional activity and shapes Th17 pathogenicity in autoimmunity

NHEJ系统对DNA双链断裂的感知可稳定RORγt转录活性，并影响Th17在自身免疫中的致病性。

Barrier-disrupting microneedle technology: Overcoming physical, physiological, and pathological skin defenses to enhance therapeutic efficacy

屏障破坏型微针技术：克服皮肤的物理、生理和病理防御机制，提升治疗效果

Viral SAM-binding proteins nsp14 and NP868R reprogram ATG4A-dependent autophagy from antiviral LC3B activity to GABARAP-mediated mitophagy.

病毒 SAM 结合蛋白 nsp14 和 NP868R 将 ATG4A 依赖性自噬从抗病毒 LC3B 活性重编程为 GABARAP 介导的线粒体自噬。

Breaking the activity-stability limit in acidic oxygen evolution reaction with dual-iridium active sites

利用双铱活性位点突破酸性析氧反应的活性-稳定性极限

Tunable Colloidal Synthesis Enabling μ-ARPES on Individual Bismuth Nanocrystals

可调控胶体合成实现对单个铋纳米晶体的μ-ARPES研究

Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9(+) macrophages via the mTORC1-C/EBPβ-OSM axis

雷帕霉素通过 mTORC1-C/EBPβ-OSM 轴重编程 Cxcl9(+) 巨噬细胞，从而在自身免疫性心肌炎中维持心脏功能。

The cGAS-STING pathway at the crossroads of neuroimmunology: bridging innate immunity to aging and neurodegeneration

cGAS-STING通路处于神经免疫学的十字路口：连接先天免疫与衰老和神经退行性疾病