日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting cholesterol-driven immunometabolism in cancer: from molecular circuits to clinical translation

靶向胆固醇驱动的癌症免疫代谢：从分子回路到临床转化

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-026-02631-8
Ma, Qiang; Chen, Bonan; Li, Tingting; Lu, Yanhui; Li, Xiaoguang
肿瘤
肿瘤免疫
代谢
免疫代谢
免疫/内分泌
发表日期：2026
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Vebreltinib for Previously Treated Astrocytoma, IDH-Mutant, Grade 4, and Glioblastoma, IDH Wild-Type with PTPRZ1-MET Fusion Gene: A Multicenter, Phase III Randomized, Open-Label Trial

维布瑞替尼治疗既往接受过治疗的星形细胞瘤（IDH突变型，4级）和胶质母细胞瘤（IDH野生型，伴PTPRZ1-MET融合基因）：一项多中心、III期随机、开放标签试验

期刊:Cancer Communications
影响因子:24.9
doi:10.34133/cancomm.0019
Bao, Zhaoshi; Xue, Yake; Liu, Yanhui; Li, Shouwei; Wang, Liang; Qu, Yan; Mou, Yonggao; Yu, Rutong; Wu, Jinsong; Yao, Yu; Shu, Kai; Hu, Guangyuan; Cai, Linbo; Li, Wenbin; Qiu, Xiaoguang; Li, Yunqian; Zhang, Lei; Qi, Songtao; Ji, Ying; Ma, Chunxiao; Ma, Wenbin; Li, Gang; Tao, Rongjie; Sun, Chongran; Chen, Ligang; Lv, Sheng-Qing; Liang, Peng; Pan, Hao; Peter, Woo Yat Ming; Danny, Chan Tat Ming; Mao, Qing; Wei, Xinting; Jiang, Tao
细胞生物学
MET
TPR
发表日期：2026
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β-Catenin regulates distinct pathways from YAP and suppresses ONECUT1 to drive hepatoblastoma development in mice and humans

β-catenin 调控的信号通路与 YAP 不同，它通过抑制 ONECUT1 来促进小鼠和人类肝母细胞瘤的发生发展。

期刊:Hepatology
影响因子:15.8
doi:10.1097/HEP.0000000000001280
Liao, Weiting; Zhang, Yi; Wang, Jingxiao; Cui, Guofei; Evert, Matthias; Xu, Meng; Wu, Yanhui; Wang, Xue; Deng, Shanshan; Song, Xinhua; Monga, Satdarshan P; Zhao, Jinqiu; Li, Qiu; Calvisi, Diego F; Chen, Xin
YAP
信号转导
细胞生物学
发表日期：2026
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In-situ formatting benzisoxazole-linked covalent organic framework for enhanced photocatalytic hydrogen peroxide generation

原位形成苯并异噁唑连接的共价有机框架以增强光催化过氧化氢的生成

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70161-4
Zhang, Pu; Zeng, Haihua; Zhang, Qiang; Wang, Peifang; Che, Huinan; Tang, Chunmei; Xu, Jingjing; Long, Jinlin; Liu, Bin; Ao, Yanhui
发表日期：2026
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Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels

通过构建果蝇组织特异性代谢模型，揭示了高糖饮食诱导的肌肉代谢紊乱，这种紊乱发生在反应和通路层面。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68395-3
Moon, Sun Jin; Hu, Yanhui; Dzieciatkowska, Monika; Kim, Ah-Ram; Asara, John M; D'Alessandro, Angelo; Perrimon, Norbert
Drosophila
信号转导
代谢
发表日期：2026
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Editorial Expression of Concern: Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

社论关注：Smad4 的缺失通过 miRNA 调控解除 PAK3 的抑制，从而促进侵袭性肺癌转移。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-71023-9
Tan, Xiaohong; Tong, Lu; Li, Lin; Xu, Jinjin; Xie, Shaofang; Ji, Lei; Fu, Junjiang; Liu, Qingwu; Shen, Shihui; Liu, Yun; Xiao, Yanhui; Gao, Feiran; Moses, Robb E; Bardeesy, Nabeel; Wang, Yanxiao; Zhang, Jishuai; Tang, Longying; Li, Lei; Wong, Kwok-Kin; Song, Dianwen; Yang, Xiao; Liu, Jian; Li, Xiaotao
肺癌
肿瘤
肿瘤免疫
PAK3
信号转导
miRNA
发表日期：2026
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The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth

果蝇前胃缺乏干细胞，但通过内复制介导的细胞生长来补偿与年龄相关的细胞丢失。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68876-5
Ewen-Campen, Ben; Chen, Weihang; Tattikota, Sudhir Gopal; Liu, Ying; Hu, Yanhui; Perrimon, Norbert
Drosophila
细胞生物学
发育与干细胞
干细胞
发表日期：2026
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Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar.

巨噬细胞产生的乳酸通过 MCT1 启动的组蛋白 H3 赖氨酸 23 乳酸化，驱动皮肤真皮成纤维细胞表型重塑，形成肥厚性瘢痕。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69388-y
Yuan Yixuan, Xiao Yujie, Zou Jie, Luo Liang, Li Mengyang, Shen Kuo, Wei Lai, Zhang Yihao, Wang Peng, Chen Yan, Zhuo Shixuan, Zhang Hao, Song Shijie, Jia Yanhui, Wang Kejia, Jiang Shiqing, Guan Hao, Hu Dahai
巨噬细胞
成纤维细胞
巨噬细胞
乳酸化
细胞生物学
免疫/内分泌
发表日期：2026
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Development and multicenter validation of an explainable machine learning diagnostic criteria for pediatric abdominal sepsis

开发和多中心验证用于儿科腹部脓毒症的可解释机器学习诊断标准

期刊:npj Digital Medicine
影响因子:15.1
doi:10.1038/s41746-026-02500-0
Cao, Suqi; Cai, Duote; Zhang, Shuhao; He, Yuchen; Yuan, Xiaojian; Zhu, Zhiqiang; Miao, Xuefeng; Wu, Shannan; Zhong, Yongxing; Yang, Fangyan; Yin, Guofeng; Yan, Juying; Chen, Junjie; Hu, Donglai; Yu, Menglu; Zhou, Zhijian; Ruan, Qiongjie; Xuan, Boyun; Cai, Yihao; Tao, Liangting; Zhang, Weiwei; Yu, Ting; Zhou, Junfen; Song, Wei; Tong, Yanwei; Tian, Yanhui; Zhou, Chunting; Wu, Dingfeng; Ma, Daqing; Gao, Zhigang
炎症/感染
败血症
发表日期：2026
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Engineered bacteria reprogram tumor microenvironment via cell senescence and neutrophil extracellular traps degradation

工程改造的细菌通过诱导细胞衰老和降解中性粒细胞胞外陷阱来重编程肿瘤微环境。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2026.01.030
Dong, Wanfa; Li, Chenyang; Lu, Jiqiang; Weng, Lin; Xu, Yicong; Xu, Min; Li, Peiqi; Wu, Yanhui; Shan, Zixuan; Shang, Pengyou; Dai, Liangliang; Zhang, Tao; Jia, Yanlong; Wang, Tianyun; Ren, Wenjie; Lu, Ping; Chen, Xiao; Hua, Zichun
微生物学
中性粒细胞
衰老
细胞生物学
细胞衰老
肿瘤微环境
肿瘤免疫
肿瘤
粒细胞
发表日期：2026
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