日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PEAKS activation by PROTAC EPIC-0726 potentiates temozolomide in glioblastoma via K63/K48 ubiquitination-dependent ERK/AKT suppression and p21 stabilization

PROTAC EPIC-0726 通过 K63/K48 泛素化依赖的 ERK/AKT 抑制和 p21 稳定增强 PEAKS 激活，从而增强替莫唑胺在胶质母细胞瘤中的疗效。

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noaf253
Hong, Biao; Su, Dongyuan; Cui, Xiaoteng; Zhao, Jixing; Wang, Qixue; Zhan, Qi; Yang, Eryan; Yang, Shixue; Ju, Jiasheng; Huang, Yanping; Cheng, Chunchao; Ding, Yaqing; Xu, Hanyi; Cui, Longtao; Zhao, Yilin; Zhao, Xun; Liang, Siwen; Liu, Yuhao; Kang, Chunsheng
AKT
表观遗传
泛素化
细胞生物学
MAPK/ERK
发表日期：2026
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Linagliptin synergizes with cPLA2 inhibition to enhance temozolomide efficacy by interrupting DPP4-mediated EGFR stabilization in glioma.

利格列汀与 cPLA2 抑制剂协同作用，通过干扰 DPP4 介导的 EGFR 在胶质瘤中的稳定作用来增强替莫唑胺的疗效

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.05.012
Su Dongyuan, Hong Biao, Yang Shixue, Zhao Jixing, Cui Xiaoteng, Zhan Qi, Yi Kaikai, Huang Yanping, Ju Jiasheng, Yang Eryan, Wang Qixue, Zhou Junhu, Wang Yunfei, Liu Xing, Kang Chunsheng
肿瘤
胶质瘤
EGFR
肿瘤免疫
发表日期：2025
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AQB improves carboplatin sensitivity in endometrial cancer through dual DNA repair modulation: suppression of the p21-E2F1-RAD51 and ATF3-HDAC1-BRCA1 signaling

AQB通过双重DNA修复调节提高子宫内膜癌对卡铂的敏感性：抑制p21-E2F1-RAD51和ATF3-HDAC1-BRCA1信号通路

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08287-4
Zheng, Xingyu; Yang, Eryan; Yan, Ye; Zhao, Shuangshuang; Li, Xianxian; Wang, Tianqi; Piao, Yuening; Liu, Wei; Chen, Jiaxin; Wen, Sitong; Gao, Chao; Tian, Wenyan; Xue, Fengxia; Kang, Chunsheng; Wang, Yingmei
肿瘤
HDAC1
子宫内膜癌
肿瘤免疫
信号转导
E2F1
BRCA1
RAD51
发表日期：2025
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The Value of Integrating Hormone Receptors into Immunohistochemistry-Based Simplified Molecular Classification in Endometrial Cancer

将激素受体整合到基于免疫组织化学的简化分子分型中对子宫内膜癌的价值

期刊:Cancer Management and Research
影响因子:2.6
doi:10.2147/CMAR.S514680
Zhao, Shuangshuang; Yan, Ye; Wang, Tianqi; Zhang, Jingying; Zheng, Xingyu; Li, Xianxian; Zhao, Jianzhen; Yang, Eryan; Zhao, Xue; Tian, Lina; Xue, Fengxia; Tian, Wenyan; Wang, Yingmei
肿瘤
IHC
子宫内膜癌
肿瘤免疫
信号转导
免疫/内分泌
发表日期：2025
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HIF1α/ATF3 partake in PGK1 K191/K192 succinylation by modulating P4HA1/succinate signaling in glioblastoma

HIF1α/ATF3通过调节胶质母细胞瘤中的P4HA1/琥珀酸信号通路参与PGK1 K191/K192的琥珀酰化。

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noae040
Yang, Shixue; Zhan, Qi; Su, Dongyuan; Cui, Xiaoteng; Zhao, Jixing; Wang, Qixue; Hong, Biao; Ju, Jiasheng; Cheng, Chunchao; Yang, Eryan; Kang, Chunsheng
信号转导
细胞生物学
琥珀酰化
发表日期：2024
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EPIC-1042 as a potent PTRF/Cavin1-caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for glioblastoma

EPIC-1042 是一种强效的 PTRF/Cavin1-caveolin-1 相互作用抑制剂，可诱导 PARP1 自噬降解并抑制替莫唑胺外排，用于治疗胶质母细胞瘤。

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noad159
Hong, Biao; Yang, Eryan; Su, Dongyuan; Ju, Jiasheng; Cui, Xiaoteng; Wang, Qixue; Tong, Fei; Zhao, Jixing; Yang, Shixue; Cheng, Chunchao; Xin, Lei; Xiao, Menglin; Yi, Kaikai; Zhan, Qi; Ding, Yaqing; Xu, Hanyi; Cui, Longtao; Kang, Chunsheng
PARP
细胞生物学
PARP1
自噬
发表日期：2024
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Retraction of "Universal theranostic CRISPR/Cas13a RNA-editing system for glioma"

撤回“用于胶质瘤的通用诊疗一体化 CRISPR/Cas13a RNA 编辑系统”

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.96658
Wu, Ye; Wang, Yunfei; Zhou, Junhu; Wang, Jianhao; Zhan, Qi; Wang, Qixue; Yang, Eryan; Jin, Weili; Tong, Fei; Zhao, Jixing; Hong, Biao; Liu, Junrui; Kang, Chunsheng
胶质瘤
RNA 编辑
发表日期：2024
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Retraction Notice to: Precise editing of FGFR3-TACC3 fusion genes with CRISPR-Cas13a in glioblastoma

撤稿声明：利用 CRISPR-Cas13a 技术精确编辑胶质母细胞瘤中的 FGFR3-TACC3 融合基因

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.04.032
Wu, Ye; Jin, Weili; Wang, Qixue; Zhou, Junhu; Wang, Yunfei; Tan, Yanli; Cui, Xiaoteng; Tong, Fei; Yang, Eryan; Wang, Jian; Kang, Chunsheng
细胞生物学
FGFR3
发表日期：2024
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A novel compound EPIC-0412 reverses temozolomide resistance via inhibiting DNA repair/MGMT in glioblastoma

一种新型化合物 EPIC-0412 通过抑制胶质母细胞瘤中的 DNA 修复/MGMT 来逆转替莫唑胺耐药性

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noac242
Zhao, Jixing; Yang, Shixue; Cui, Xiaoteng; Wang, Qixue; Yang, Eryan; Tong, Fei; Hong, Biao; Xiao, Menglin; Xin, Lei; Xu, Can; Tan, Yanli; Kang, Chunsheng
细胞生物学
MGMT
发表日期：2023
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Universal theranostic CRISPR/Cas13a RNA-editing system for glioma

用于胶质瘤的通用型诊疗一体化 CRISPR/Cas13a RNA 编辑系统

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.84429
Wu, Ye; Wang, Yunfei; Zhou, Junhu; Wang, Jianhao; Zhan, Qi; Wang, Qixue; Yang, Eryan; Jin, Weili; Tong, Fei; Zhao, Jixing; Hong, Biao; Liu, Junrui; Kang, Chunsheng
胶质瘤
RNA 编辑
发表日期：2023
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