Mitochondrial calcium uniporter promotes MSU crystal-induced inflammation through inducing mitochondrial Ca(2+) overload and ubiquitination of SIRT5 protein.
线粒体钙单向转运蛋白通过诱导线粒体 Ca(2+) 超载和 SIRT5 蛋白泛素化促进 MSU 晶体诱导的炎症
期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-025-03627-3
Yu Qingqing, Li Renjie, Yang Guizhao, Xiao Yan, Liu Xingyu, Deng Yaxin, Luo Xiongyan, Dai Qian, Zeng Mei
