日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bridging the barrier: insights into blood biomarkers and therapeutic strategies targeting choroid plexus and BBB dysfunction in alzheimer's disease

弥合障碍:深入了解阿尔茨海默病中针对脉络丛和血脑屏障功能障碍的血液生物标志物和治疗策略

Sharma, Niti; Kim, Danyeong; Sharma, Himadri; Kim, Moon Il; Lee, Hyon; Kim, Minju; Ryoo, Nayoung; Kang, Min Ju; Pyun, Jung-Min; Park, Young Ho; Ryu, Jisun; Oh, Hyun Jung; Yang, Hyun-Sik; Kim, Hang-Rai; Kim, Geon Ha; Han, Sangwon; Yang, YoungSoon; Youn, Young Chul; Teunissen, Charlotte; Zetterberg, Henrik; Scheltens, Philip; An, Seong Soo A; Kim, Young-Bum; Kim, SangYun

Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline

P-Tau217、Tau蛋白聚集和认知衰退中的性别差异

Coughlan, Gillian T; Ourry, Valentin; Townsend, Diana; Klinger, Hannah; Brown, Jane A; Cuppels, Madison; Betthauser, Tobey; Langhough, Rebecca; Cody, Karly; Seto, Mabel; Birkenbihl, Colin; Li, Annie; Farrell, Michelle; Thibault, Emma; Kivisäkk Webb, Pia; Arnold, Steven; Rissman, Robert A; Properzi, Michael; Schultz, Aaron; Johnson, Keith; Langford, Oliver; Donohue, Michael C; Villeneuve, Sylvia; Johnson, Sterling C; Yang, Hyun-Sik; Manson, JoAnn E; Sperling, Reisa; Buckley, Rachel F

Plasma phosphorylated tau 217 and longitudinal trajectories of Aβ, tau, and cognition in cognitively unimpaired older adults

血浆磷酸化tau蛋白217与认知功能正常老年人Aβ、tau蛋白和认知功能的纵向变化轨迹

Yang, Hyun-Sik; Anzai, Juliana A U; Yau, Wai-Ying Wendy; Healy, Brian C; Román Viera, Andrea M; Maa, Courtney; Kirn, Dylan; Properzi, Michael J; Bellier, Jean-Pierre; Schultz, Aaron P; Farrell, Michelle E; Jacobs, Heidi I L; Buckley, Rachel F; Papp, Kathryn V; Marshall, Gad A; Amariglio, Rebecca E; Rentz, Dorene M; Liu, Lei; Selkoe, Dennis J; Verghese, Philip B; Braunstein, Joel B; Johnson, Keith A; Sperling, Reisa A; Chhatwal, Jasmeer P

Elevated temporal tau PET predicts faster cognitive decline in women than men: A meta-analysis

颞叶 tau 蛋白 PET 升高预示女性认知能力下降速度快于男性:一项荟萃分析

Li, Annie; Klinger, Hannah M; Seto, Mabel; Birkenbihl, Colin; Properzi, Michael J; Farrell, Michelle; Thibault, Emma; Schultz, Aaron P; Townsend, Diana L; Cuppels, Madison; Brown, Jane A; Papp, Kathryn V; Amariglio, Rebecca E; Yang, Hyun-Sik; Donohue, Michael C; Rissman, Robert A; Betthauser, Tobey J; Langhough, Rebecca E; Jonaitis, Erin M; Cody, Karly; Johnson, Sterling C; Rentz, Dorene M; Johnson, Keith A; Sperling, Reisa A; Buckley, Rachel F; Coughlan, Gillian T

Whole blood gene expression moderates associations between AD biomarkers and cognitive decline in cognitively unimpaired older adults

全血基因表达调节认知功能正常的年长者中阿尔茨海默病生物标志物与认知衰退之间的关联

Klinger, Hannah M; Seto, Mabel; Janve, Vaibhav A; Brown, Jane A; Clifton, Michelle; Birkenbihl, Colin; Coughlan, Gillian T; Townsend, Diana L; Properzi, Michael; Zyski, Jane; Wang, Ting-Chen; Amariglio, Rebecca E; Papp, Kathryn V; Rentz, Dorene M; Yang, Hyun-Sik; Chhatwal, Jasmeer; Donohue, Michael C; Raman, Rema; Rissman, Robert A; Aisen, Paul; Johnson, Keith A; Sperling, Reisa A; Dumitrescu, Logan; Hohman, Timothy; Buckley, Rachel F

Association of Aβ monomers with cerebral amyloid angiopathy in brains without parenchymal Aβ deposition

在无实质Aβ沉积的脑组织中,Aβ单体与脑淀粉样血管病相关。

Liu, Lei; Yu, Lei; Petyuk, Vladislav A; Kapasi, Alifiya; Yoo, Han Bin; Saba, Adriana; Yang, Hyun-Sik; Chhatwal, Jasmeer P; Bennett, David A

The prognostic value of blood-based p-tau217 levels on progression to clinical impairment

血液中p-tau217水平对临床损害进展的预后价值

Buckley, Rachel F; Townsend, Diana L; Birkenbihl, Colin J; Cuppels, Madison; Coughlan, Gillian T; Seto, Mabel T; Brown, Jane A; Properzi, Michael J; Hönig, Merle C; Li, Annie; Schultz, Aaron P; Chhatwal, Jasmeer; Yang, Hyun-Sik; Arnold, Steven; Kivisäkk, Pia; James, Bryan D; O'Bryant, Sid; Rissman, Robert A; Petersen, Melissa; Caldwell, Jessica Z K; Betthauser, Tobey; Oomens, Julie Elisabeth; Carrigan, Maria; Healy, Brian; Condado, Jorge Garcia; Johnson, Sterling; Yau, Wai-Ying Wendy; Langford, Oliver; Farrell, Michelle; Amariglio, Rebecca E; Rentz, Dorene M; Papp, Kathryn V; Hohman, Timothy J; Donohue, Michael; Aisen, Paul S; Johnson, Keith A; Sperling, Reisa A

Plasma TDP-43 is a potential biomarker for advanced limbic-predominant age-related TDP-43 encephalopathy neuropathologic change

血浆TDP-43是晚期边缘系统为主的年龄相关性TDP-43脑病神经病理学改变的潜在生物标志物。

Wang, Jijing; Schneider, Julie A; Bennett, David A; Seyfried, Nicholas T; Young-Pearse, Tracy L; Yang, Hyun-Sik

Microglia‐specific Alzheimer's disease polygenic risk score predicts longitudinal increase in plasma tau and faster cognitive decline in cognitively unimpaired older adults

小胶质细胞特异性阿尔茨海默病多基因风险评分可预测认知功能正常的成年人血浆tau蛋白的纵向升高和认知功能下降速度加快。

Zhang, Changlong; Li, Yuxuan; Wang, Yang; Hu, Shourui; Liu, Yue; Liang, Xiaofan; Chen, Zi-Jiang; Zhang, Yuqing; Zhao, Han; Kumar, Rajeswar; Rashid, Tanweer; Charisis, Sokratis; Li, Karl; Ho, Ngoc‐Huynh; Brandigampala, Sachintha Ransara; Toga, Arthur W; Kukull, Walter W; Risacher, Shannon L; Wang, Di; Mojtabai, Mariam; Honnorat, Nicolas; Archer, Derek B; Tosun, Duygu; Wang, David H; Bennett, David A A; Martinez, David M; Jefferson, Angela L; Resnick, Susan M; Saykin, Andrew J; Seshadri, Sudha; Cuccaro, Michael L; Davatzikos, Christos; Hohman, Timothy J; Habes, Mohamad; Mustafa, Yousef; Mews, Makaela; Gu, Tianjie; Gomez, Lissette; Adams, Larry D; Starks, Takiyah D; Cornejo‐Olivas, Mario; Illanes‐Manrique, Maryenela Z; Silva‐Vergara, Concepcion; Feliciano‐Astacio, Briseida E; Byrd, Goldie S; Pericak‐Vance, Margaret; Haines, Jonathan L; Griswold, Anthony J; Bush, William S; Mendez, Brahyan J Galindo; Teng, Ling; Marshall, Gad A; Liu, Lei; Chhatwal, Jasmeer P; Hohman, Timothy J; Mayeux, Richard; Jager, Philip L De; Rissman, Robert A; Johnson, Keith A; Sperling, Reisa A; Yang, Hyun‐Sik

Dementia prevalence and risk factors in people with and without HIV in Malawi: A medical record review

马拉维艾滋病毒感染者和非感染者痴呆症患病率及危险因素:一项医疗记录回顾研究

Lee, Haeok; Mlombe, Yohannie; Song, Yeunjoo E; Yang, Hyun-Sik; Phiri, Tiwonge; Maseke, Joseph; Bauleni, Ether; Jun, Gyungah R; Choi, Yun-Beom; Ngoma, Jonathan