Yang Jian-Jun相关文献与解析，生知库 | 链接生命科学的每一步

Polydopamine nanoparticles restore cognition via targeted dopamine delivery and septo-hippocampal cholinergic activation.

聚多巴胺纳米颗粒通过靶向输送多巴胺和激活隔区-海马胆碱能来恢复认知功能。

Liu Pan-Miao, Wang Yu-Ge, Zhu Ting-Ting, Zhang Ji-Chun, Gu Han-Wen, Li Hui-Juan, Pan Wei-Tong, Zhou Yan-Bo, Zhu Kui-Cheng, Hashimoto Kenji, Yang Jian-Jun

Hippo

发表日期：2026

文献求助收藏

Flos sophorae immaturus exosome-like nanovesicles alleviate ulcerative colitis by attenuating intestinal oxidative stress and inflammation through activating Aryl hydrocarbon receptor via gut microbiota and tryptophan metabolism regulation

苦参外泌体样纳米囊泡通过激活芳烃受体，进而调节肠道菌群和色氨酸代谢，减轻肠道氧化应激和炎症，从而缓解溃疡性结肠炎。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04083-0

Wu, Hao; Pang, Mi-Mi; Li, Yao-Lei; Huang, Jin-Jian; Geng, Shi-Zhen; Hong, Jia-Hui; Liu, Pan-Miao; Yang, Jian-Jun

Early-life microbiota dysbiosis as a link between Autism Spectrum Disorder and Parkinson's Disease

早期肠道菌群失调是自闭症谱系障碍与帕金森病之间的联系

期刊:Molecular Psychiatry

影响因子:10.1

doi:10.1038/s41380-025-03281-w

Zhao, Ming-Ming; Hashimoto, Kenji; Yang, Jian-Jun

Chronic pain and risk of cognitive impairment: a meta-analysis of longitudinal cohort studies

慢性疼痛与认知障碍风险：一项纵向队列研究的荟萃分析

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-026-03924-8

Qiu, Di; Zhou, Zhang-Bing; Li, Xin-Yu; Hashimoto, Kenji; Yang, Jian-Jun; Wang, Xing-Ming

神经科学

发表日期：2026

文献求助收藏

Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study

利用对比增强超声技术从粘性注射微泡中持续释放罗哌卡因治疗疼痛：一项动物模型研究

期刊:Drug Design Development and Therapy

影响因子:5.1

doi:10.2147/DDDT.S532749

Shang, Hui-Jie; Ye, Hao-Tian; Yue, Cai-Bao; Ji, Mu-Huo; Gu, Han-Wen; Pan, Wei-Tong; Liu, Pan-Miao; Yang, Jian-Jun

发表日期：2026

文献求助收藏

HDAC3 Mediates Hippocampal Microglial Pyroptosis Via the STING/NLRP3 Pathway and Contributes To Cognitive Impairment in Sepsis-Associated Encephalopathy.

HDAC3 通过 STING/NLRP3 通路介导海马小胶质细胞焦亡，并导致脓毒症相关脑病中的认知障碍。

期刊:Inflammation

影响因子:5

doi:10.1007/s10753-025-02360-y

Cai Meng, Shao Hua, Xu Shan, Wang He, Yang Meng-Jie, Zhu Tong, Chen Jiang, Li Gui-Zhou, Lu Shuai-Fei, Zang Yan-Yu, Ji Mu-Huo, Shen Jin-Chun, Jia Min, Yang Jian-Jun

Clec7a Drives Microglial Activation-Mediated Myelin Degradation in Sepsis-Associated Encephalopathy.

Clec7a 驱动小胶质细胞活化介导的脓毒症相关性脑病中的髓鞘降解。

期刊:Inflammation

影响因子:5

doi:10.1007/s10753-025-02443-w

Jian Jia-Xiong, Yin Xiao-Yu, Mei Xu-Dong, Yang Jian-Jun, Ji Mu-Huo, Shen Jin-Chun

Predicting postoperative delirium after lung cancer resection: the utility of synthetic data and LIME algorithm for model interpretation

预测肺癌切除术后谵妄：合成数据和LIME算法在模型解释中的应用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-24848-1

Zhu, Yu; Liang, Renrui; Yang, Jian-Jun; Zhou, Cheng-Mao

Esketamine combined with hydromorphone versus hydromorphone for post-operative patient-controlled intravenous analgesia in children: a randomized controlled trial

艾司氯胺酮联合氢吗啡酮与氢吗啡酮单药治疗儿童术后患者自控静脉镇痛的疗效比较：一项随机对照试验

期刊:European Journal of Medical Research

影响因子:3.4

doi:10.1186/s40001-025-03806-7

Li, Yang; Wang, Lingling; Liu, Kun; Gao, Wenjian; Zhang, Yue; Yang, Jinjin; Yang, Jian-Jun

发表日期：2026

文献求助收藏

Applications of micro/nano drug delivery systems in cancer pain management

微/纳米药物递送系统在癌症疼痛管理中的应用

Polydopamine nanoparticles restore cognition via targeted dopamine delivery and septo-hippocampal cholinergic activation.

聚多巴胺纳米颗粒通过靶向输送多巴胺和激活隔区-海马胆碱能来恢复认知功能。

Flos sophorae immaturus exosome-like nanovesicles alleviate ulcerative colitis by attenuating intestinal oxidative stress and inflammation through activating Aryl hydrocarbon receptor via gut microbiota and tryptophan metabolism regulation

苦参外泌体样纳米囊泡通过激活芳烃受体，进而调节肠道菌群和色氨酸代谢，减轻肠道氧化应激和炎症，从而缓解溃疡性结肠炎。

Early-life microbiota dysbiosis as a link between Autism Spectrum Disorder and Parkinson's Disease

早期肠道菌群失调是自闭症谱系障碍与帕金森病之间的联系

Chronic pain and risk of cognitive impairment: a meta-analysis of longitudinal cohort studies

慢性疼痛与认知障碍风险：一项纵向队列研究的荟萃分析

Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study

利用对比增强超声技术从粘性注射微泡中持续释放罗哌卡因治疗疼痛：一项动物模型研究

HDAC3 Mediates Hippocampal Microglial Pyroptosis Via the STING/NLRP3 Pathway and Contributes To Cognitive Impairment in Sepsis-Associated Encephalopathy.

HDAC3 通过 STING/NLRP3 通路介导海马小胶质细胞焦亡，并导致脓毒症相关脑病中的认知障碍。

Clec7a Drives Microglial Activation-Mediated Myelin Degradation in Sepsis-Associated Encephalopathy.

Clec7a 驱动小胶质细胞活化介导的脓毒症相关性脑病中的髓鞘降解。

Predicting postoperative delirium after lung cancer resection: the utility of synthetic data and LIME algorithm for model interpretation

预测肺癌切除术后谵妄：合成数据和LIME算法在模型解释中的应用

Esketamine combined with hydromorphone versus hydromorphone for post-operative patient-controlled intravenous analgesia in children: a randomized controlled trial

艾司氯胺酮联合氢吗啡酮与氢吗啡酮单药治疗儿童术后患者自控静脉镇痛的疗效比较：一项随机对照试验