日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Carrier free oral Co-delivery of atorvastatin via baicalein-copper-network for atherosclerosis therapy through senescence reversal and multi-mechanistic synergy.

通过黄芩苷-铜网络无载体口服共递送阿托伐他汀，以逆转衰老和多机制协同作用治疗动脉粥样硬化。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2025.12.036
Liu Kaijing, Li Gen, Liang Xiaoyu, Wang Changduo, Zhu Ni, Fu Xue, Zhang Yujie, Liu Chao, Yang Jing
动脉粥样硬化
衰老
发育与干细胞
Senescence
发表日期：2026
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Representational dynamics during extinction of fear memories in the human brain

人类大脑中恐惧记忆消退过程中的表征动力学

期刊:Nature Human Behaviour
影响因子:15.9
doi:10.1038/s41562-025-02268-5
Pacheco-Estefan, Daniel; Bouyeure, Antoine; Jacob, George; Fellner, Marie-Christin; Lehongre, Katia; Lambrecq, Virginie; Frazzini, Valerio; Navarro, Vincent; Güntürkün, Onur; Shen, Lu; Yang, Jing; Han, Biao; Chen, Qi; Axmacher, Nikolai
神经科学
发表日期：2026
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RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b(+) Bregs thereby overcoming melanoma PD1-resistance

RAS/MEK/PI3K通路抑制通过靶向CD11b(+) Bregs增强对CD40激动剂的反应，从而克服黑色素瘤PD1耐药性。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67315-1
Yan, Chi; Luo, Weifeng; Yang, Jinming; Yang, Jing; Chen, Sheau-Chiann; Bergdorf, Kensey; Hu, Qianni; Weiss, Vivian L; Johnson, Douglas B; Liu, Qi; Richmond, Ann
黑色素瘤
T细胞
信号转导
CD40
RAS
CD4
发表日期：2026
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Timosaponin AIII enhances CAR-T cell potency and prevents relapse through impairing CAR-Tregs

铁木皂苷AIII通过抑制CAR-Treg细胞增强CAR-T细胞的效力并预防复发。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70867-5
Hou, Mingqi; Zhang, Wenjun; Qi, Ziping; Li, Guiming; Mei, Husheng; Qi, Shuang; Jin, Rui; Zhao, Yuedong; Tang, Xiaochen; Xiu, Bing; Chen, Xiaotong; Zhao, Yunshuo; Hu, Chen; Qian, Changlin; Li, Xiuchun; Xu, Zhan; Chen, Yongfei; Wu, Chao; Wang, Beilei; Yan, Lejin; Li, Dan; Huang, Yushan; Liang, Rui; Wang, Aoli; Liu, Jing; Wang, Wenchao; Li, Bin; Long, Jun; Li, Ping; Liang, Aibin; Liu, Qingsong; Yang, Jing
T细胞
Treg
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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MerTK-triggered TGFβ1 autocrine signal regulates microglial response to neurodegeneration.

MerTK触发的TGFβ1自分泌信号调节小胶质细胞对神经退行性疾病的反应。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69189-3
Huang Yingying, Deng Zhangyuzi, Zhou Zhijie, Fu Koukou, Liu Fuhai, Zhang Haoyue, Chen Jian, Yang Jing, Cao Ying
胶质细胞
信号转导
神经科学
细胞生物学
Mer
TGFβ
发表日期：2026
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Integrating multi-omics and machine learning systematically deciphers cellular heterogeneity and fibrotic regulatory networks in the progression from MASLD to MASH

整合多组学和机器学习技术，系统性地解析了MASLD向MASH进展过程中的细胞异质性和纤维化调控网络。

期刊:npj Digital Medicine
影响因子:15.1
doi:10.1038/s41746-026-02352-8
Wen, Weiheng; Liu, Zenghui; Tan, Wenliang; Tan, Yingzheng; Li, Wei; Wan, Jian; Hu, Hongsai; Jiang, Zhengwu; Tang, Xing; Yang, Jing; Xiao, Jiao; Tan, Xiongjin; Chen, Xun; Wu, Peili; Li, Yukun
信号转导
细胞生物学
发表日期：2026
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RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b+ Bregs thereby overcoming melanoma PD1-resistance

RAS/MEK/PI3K通路抑制通过靶向CD11b+ Bregs增强对CD40激动剂的反应，从而克服黑色素瘤PD1耐药性。

期刊:
影响因子:14.7
doi:PMC12796310
Chi Yan ，Weifeng Luo，Jinming Yang，Jing Yang，Sheau-Chiann Chen，Kensey Bergdorf，Qianni Hu，Vivian L Weiss，Douglas B Johnson，Qi Liu，Ann Richmond
黑色素瘤
信号转导
CD4
CD40
RAS
CD11B
PI3K/Akt
发表日期：2026
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Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation.

蛋白毒性应激通过非经典的 MTORC1 失活触发 TFEB 和 TFE3 介导的自噬和溶酶体生物合成。

期刊:Autophagy
影响因子:14.3
doi:10.1080/15548627.2025.2608973
Zhu Zhou, Yang Jing, Montefusco Sandro, Xia Siyu, Ou Jinhuan, Tong Haibo, Zeng Qingzhong, Xu Fengmei, Dai Lingyun, Sun Jichao, Xu Chengchao, Medina Diego Luis, Wang Jigang, Zhang Wei, Yang Chuanbin
表观遗传
MTOR
ORC1
TFE3
TFEB
Autophagy
mTOR
自噬
发表日期：2026
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Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

棉花中染色质拓扑重构通过GhAL5调控雄性耐热生育能力。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202507766
Li, Yanlong; Yang, Jing; Wang, Weiran; Zuo, Chunyang; Pei, Liuling; Ma, Yizan; Zhang, Rui; Fan, Yaru; Ma, Huanhuan; Li, Yawei; Liu, Ruizhen; Jin, Shuangxia; Zhu, Longfu; Kong, Jie; Zhang, Xianlong; Min, Ling
信号转导
发表日期：2026
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Targeting DESI2 as a Novel Therapeutic Strategy for JAK2-Mutant Leukemias

以DESI2为靶点治疗JAK2突变型白血病的新型治疗策略

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202515127
Mei, Husheng; Wen, Wuqiang; Zhang, Wenjun; Zhang, Shujing; Sun, Ting; Li, Guiming; Zhang, Jing; Qi, Shuang; Zhou, Jie; Li, Bing; Zhao, Yunshuo; Chen, Xiaotong; Li, Bowen; Xue, Yiying; Lu, Wang; Sun, Yanli; Wang, Jingyao; Shan, Hengyue; Zhang, Shengzhe; Huang, Yushan; Chen, Yisa; Wang, Wenchao; Liu, Qingsong; Lu, Wenchao; Tan, Li; Ding, Yi; Fu, Jianfei; Long, Jun; Zhang, Lei; Zhao, Baobing; Liang, Aibin; Jiang, Baishan; Yang, Jing
白血病
JAK/STAT
JAK2
发表日期：2026
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