日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution

对3'UTR变异进行全基因组功能筛选,揭示了人类疾病和进化的致病变异。

Dustin Griesemer ,James R Xue ,Steven K Reilly ,Jacob C Ulirsch ,Kalki Kukreja ,Joe R Davis ,Masahiro Kanai ,David K Yang ,John C Butts ,Mehmet H Guney ,Jeremy Luban ,Stephen B Montgomery ,Hilary K Finucane ,Carl D Novina ,Ryan Tewhey ,Pardis C Sabeti

Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney

肾小球壁层上皮细胞静止状态需要足细胞特异性KLF4。

Jesse A Pace ,Robert Bronstein ,Yiqing Guo ,Yaqi Yang ,Chelsea C Estrada ,Nehaben Gujarati ,David J Salant ,John Haley ,Agnieszka B Bialkowska ,Vincent W Yang ,John C He ,Sandeep K Mallipattu

Cathepsin S Evokes PAR2-Dependent Pain in Oral Squamous Cell Carcinoma Patients and Preclinical Mouse Models

组织蛋白酶 S 在口腔鳞状细胞癌患者和临床前小鼠模型中引起 PAR2 依赖性疼痛

Nguyen Huu Tu, Kenji Inoue, Elyssa Chen, Bethany M Anderson, Caroline M Sawicki, Nicole N Scheff, Hung D Tran, Dong H Kim, Robel G Alemu, Lei Yang, John C Dolan, Cheng Z Liu, Malvin N Janal, Rocco Latorre, Dane D Jensen, Nigel W Bunnett, Laura E Edgington-Mitchell, Brian L Schmidt

Granulocyte-Colony Stimulating Factor-Induced Neutrophil Recruitment Provides Opioid-Mediated Endogenous Anti-nociception in Female Mice With Oral Squamous Cell Carcinoma

粒细胞集落刺激因子诱导的中性粒细胞募集为患有口腔鳞状细胞癌的雌性小鼠提供阿片类药物介导的内源性抗伤害作用

Nicole N Scheff, Robel G Alemu, Richard Klares 3rd, Ian M Wall, Stephen C Yang, John C Dolan, Brian L Schmidt

Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease

足细胞特异性诱导 Krüppel 样因子 15 可恢复分化标志物并减轻蛋白尿性肾病中的肾损伤

Yiqing Guo ,Jesse Pace ,Zhengzhe Li ,Avi Ma'ayan ,Zichen Wang ,Monica P Revelo ,Edward Chen ,Xiangchen Gu ,Ahmed Attalah ,Yaqi Yang ,Chelsea Estrada ,Vincent W Yang ,John C He ,Sandeep K Mallipattu

A Vitis vinifera basic helix-loop-helix transcription factor enhances plant cell size, vegetative biomass and reproductive yield

葡萄基本螺旋-环-螺旋转录因子可增加植物细胞大小、营养生物量和生殖产量

Sung Don Lim, Won Choel Yim, Degao Liu, Rongbin Hu, Xiaohan Yang, John C Cushman

Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation

Krüppel样因子4是STAT3诱导的肾小球上皮细胞增殖的负调控因子

Chelsea C Estrada ,Praharshasai Paladugu ,Yiqing Guo ,Jesse Pace ,Monica P Revelo ,David J Salant ,Stuart J Shankland ,Vivette D D'Agati ,Anita Mehrotra ,Stephanie Cardona ,Agnieszka B Bialkowska ,Vincent W Yang ,John C He ,Sandeep K Mallipattu

Podocyte-Specific Loss of Krüppel-Like Factor 6 Increases Mitochondrial Injury in Diabetic Kidney Disease

足细胞特异性 Krüppel 样因子 6 的缺失会增加糖尿病肾病中的线粒体损伤

Sylvia J Horne, Jessica M Vasquez, Yiqing Guo, Victoria Ly, Sian E Piret, Alexandra R Leonardo, Jason Ling, Monica P Revelo, Daniel Bogenhagen, Vincent W Yang, John C He, Sandeep K Mallipattu

The loss of Krüppel-like factor 15 in Foxd1+ stromal cells exacerbates kidney fibrosis

Foxd1+ 基质细胞中 Krüppel 样因子 15 的缺失加剧了肾脏纤维化

Xiangchen Gu, Sandeep K Mallipattu, Yiqing Guo, Monica P Revelo, Jesse Pace, Timothy Miller, Xiang Gao, Mukesh K Jain, Agnieszka B Bialkowska, Vincent W Yang, John C He, Changlin Mei

Krüppel-Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers

Krüppel 样因子 15 介导糖皮质激素诱导的足细胞分化标志物的恢复

Sandeep K Mallipattu, Yiqing Guo, Monica P Revelo, Lucia Roa-Peña, Timothy Miller, Jason Ling, Stuart J Shankland, Agnieszka B Bialkowska, Victoria Ly, Chelsea Estrada, Mukesh K Jain, Yuan Lu, Avi Ma'ayan, Anita Mehrotra, Rabi Yacoub, Edward P Nord, Robert P Woroniecki, Vincent W Yang, John C He