13C tracing in synaptosomes reveals that SGLT2 inhibition with dapagliflozin prevents metabolic deficits in the 5X-FAD model of Alzheimer's Disease.
13C 在突触体中的示踪显示，达格列净抑制 SGLT2 可预防 5X-FAD 阿尔茨海默病模型中的代谢缺陷
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doi:10.1101/2025.04.30.651373
Mekkittikul Marisa, Zhu Cansheng, Danna Bezawit T, Zuo Xiaohong, Rios Amy, Yang Krista, Villanueva Miranda, Agarwal Devanshi, Castro Daniel, Gu Xuelin, Strofs Alexander R, Shirihai Orian S, Stiles Linsey, Frautschy Sally A, Oscarsson Jan, Esterline Russell L, Cole Gregory M, Divakaruni Ajit S
