Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
脂质过量激活不变性自然杀伤T细胞,促进肥胖小鼠的组织炎症、胰岛素抵抗和肝脂肪变性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1200498109
Wu, Lan; Parekh, Vrajesh V; Gabriel, Curtis L; Bracy, Deanna P; Marks-Shulman, Pamela A; Tamboli, Robyn A; Kim, Sungjune; Mendez-Fernandez, Yanice V; Besra, Gurdyal S; Lomenick, Jefferson P; Williams, Brandon; Wasserman, David H; Van Kaer, Luc
炎症
T细胞
炎症/感染
代谢
肥胖
T细胞
细胞生物学
免疫/内分泌