High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating baseline TNF level, low drug levels, and reduced clinical responses: a post hoc analysis of the RISING study.
类风湿关节炎患者基线时类风湿因子和抗 CCP 抗体滴度较高与循环基线 TNF 水平升高、药物水平降低和临床反应减少相关:RISING 研究的事后分析
期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-017-1401-2
Takeuchi Tsutomu, Miyasaka Nobuyuki, Inui Takashi, Yano Toshiro, Yoshinari Toru, Abe Tohru, Koike Takao