日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of HIV-1 capsid polymorphisms on viral infectivity and susceptibility to lenacapavir

HIV-1衣壳多态性对病毒感染性和对来那卡帕韦敏感性的影响

Hansen, Derek; Hendricks, Matthew R; Chang, Silvia; Cai, Arthur; Perry, Jason K; Aeschbacher, Thomas; Martin, Ross; Cihlar, Tomas; Yant, Stephen R

Discovery of Lenacapavir: First-in-Class Twice-Yearly Capsid Inhibitor for HIV-1 Treatment and Pre-exposure Prophylaxis

发现莱那卡帕韦:首个用于 HIV-1 治疗和暴露前预防的每年两次给药的衣壳抑制剂

Canales, Eda; Tse, Winston; Schroeder, Scott D; Chou, Chien-Hung; Liu, Qi; Zhang, Jennifer; Lazerwith, Scott E; Morganelli, Philip; Saito, Roland D; Brizgys, Gediminas; Li, Jiayao; Wu, Qiaoyin; Graupe, Michael; Halcomb, Randall L; Desai, Manoj; Cannizzaro, Carina; Hu, Eric; Perry, Jason K; Villaseñor, Armando G; Somoza, John R; Ferrao, Ryan D; Swaminathan, S; Zheng, Jim; Lu, Bing; Mwangi, Judy; Wang, Kelly; Subramanian, Raju; Smith, Bill J; Rhodes, Gerry; Rowe, William; Sauer, Dorothea; Lad, Latesh; Papalia, Giuseppe A; Clancy, Sheila; Stepan, George J; Yu, Helen; Sakowicz, Roman; Shi, Bing; Carr, Gavin; Bam, Rujuta A; Tsai, Luong K; Singer, Eric; Hansen, Derek; Mulato, Andrew; Yant, Stephen R; Cihlar, Tomas; Link, John O

Long-acting lenacapavir acts as an effective preexposure prophylaxis in a rectal SHIV challenge macaque model

在直肠SHIV感染猕猴模型中,长效lenacapavir可作为有效的暴露前预防措施。

Bekerman, Elena; Yant, Stephen R; VanderVeen, Laurie; Hansen, Derek; Lu, Bing; Rowe, William; Wang, Kelly; Callebaut, Christian

Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir.

评价考比司他(cobicistat)对替诺福韦体外肾脏转运和细胞毒性潜力的影响

Stray Kirsten M, Bam Rujuta A, Birkus Gabriel, Hao Jia, Lepist Eve-Irene, Yant Stephen R, Ray Adrian S, Cihlar Tomas

A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8

双杂交筛选鉴定出组织蛋白酶B和L是腺相关病毒2和8的脱壳因子。

Akache, Bassel; Grimm, Dirk; Shen, Xuan; Fuess, Sally; Yant, Stephen R; Glazer, Dariya S; Park, Julie; Kay, Mark A

Postintegrative gene silencing within the Sleeping Beauty transposition system

睡美人转座系统内的整合后基因沉默

Garrison, Brian S; Yant, Stephen R; Mikkelsen, Jacob Giehm; Kay, Mark A

The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9

37/67千道尔顿层粘连蛋白受体是腺相关病毒8、2、3和9型血清型的受体。

Akache, Bassel; Grimm, Dirk; Pandey, Kusum; Yant, Stephen R; Xu, Hui; Kay, Mark A

High-resolution genome-wide mapping of transposon integration in mammals

哺乳动物转座子整合的高分辨率全基因组定位

Yant, Stephen R; Wu, Xiaolin; Huang, Yong; Garrison, Brian; Burgess, Shawn M; Kay, Mark A

Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

睡美人转座酶N端DNA结合域的突变分析:哺乳动物细胞中DNA结合和过度活性的关键残基

Yant, Stephen R; Park, Julie; Huang, Yong; Mikkelsen, Jacob Giehm; Kay, Mark A