The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF.
AMPK 抑制剂通过阻断 CRAF C 末端的磷酸化 Ser-621 来克服 RAF 抑制剂的矛盾效应
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.004597
Yuan Jimin, Ng Wan Hwa, Yap Jiajun, Chia Brandon, Huang Xuchao, Wang Mei, Hu Jiancheng
