日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study

利用基于计算机断层扫描的基础模型预测同源重组缺陷和治疗反应：一项临床前研究

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01322-3
Kuang, Sheng; Schuitmaker, Lesley; Wu, Min; Salahuddin, Zohaib; van der Wiel, Alexander; van de Laak, Jella; Lieuwes, Natasja; Biemans, Rianne; Jung, Jennifer; Yaromina, Ala; Dubois, Ludwig J; Woodruff, Henry C; Lambin, Philippe
发表日期：2026
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Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506

范可尼贫血或同源重组途径的缺陷会增强缺氧激活前药CP-506的抗肿瘤作用。

期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2026.201161
Schuitmaker, Lesley; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Mutsters, Nikki A M; Jung, Jennifer; Bastos, Victoria Claudino; Sagarra, Èlia Prades; Kuang, Sheng; Setton, Jeremy; Langie, Sabine A S; Kampen, Kim R; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe
肿瘤
贫血
肿瘤免疫
代谢
发表日期：2026
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The Effect of Dietary Fiber Compositions on the Therapeutic Outcome of Combined Radio- and Immunotherapy in a Preclinical Cancer Model

膳食纤维组成对临床前癌症模型中联合放疗和免疫疗法疗效的影响

期刊:Molecular Nutrition & Food Research
影响因子:4.2
doi:10.1002/mnfr.70370
Westheim, Annemarie J F; Dubois, Ludwig J; Prades-Sagarra, Elia; Chan, Jiyang; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Cong, Ying; Houben, Tom; Meesters, Dennis M; Yaromina, Ala; van Dijk, Miriam; van Bergenhenegouwen, Jeroen; van Helvoort, Ardy; Langen, Ramon C J; Penders, John; Shiri-Sverdlov, Ronit; Theys, Jan
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Development of a novel anti-CEACAM5 VHH for SPECT imaging and potential cancer therapy applications.

开发一种新型抗CEACAM5 VHH用于SPECT成像和潜在的癌症治疗应用

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-025-07321-z
Cong Ying, Biemans Rianne, Lieuwes Natasja G, Suijlen Dennis, Lambin Philippe, Dijkgraaf Ingrid, Bauwens Matthias, Yaromina Ala, Dubois Ludwig J
肿瘤
肿瘤免疫
发表日期：2025
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A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy

一种新型谱系追踪工具揭示，乏氧肿瘤细胞驱动放射治疗后肿瘤复发。

期刊:Radiotherapy and Oncology
影响因子:5.3
doi:10.1016/j.radonc.2024.110592
Menegakis, Apostolos; Vennin, Claire; Ient, Jonathan; Groot, Arjan J; Krenning, Lenno; Klompmaker, Rob; Friskes, Anoek; Ilic, Mila; Yaromina, Ala; Harkes, Rolf; van den Broek, Bram; Jakob Sonke, Jan; De Jong, Monique; Piepers, Jolanda; van Rheenen, Jacco; Vooijs, Marc A; Medema, René H
肿瘤细胞
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts

放射增敏剂尼莫唑联合 RCTx 治疗反应的预后生物标志物：头颈部鳞状细胞癌异种移植瘤的临床前试验

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-023-04439-2
Koi, Lydia; Bitto, Verena; Weise, Corina; Möbius, Lisa; Linge, Annett; Löck, Steffen; Yaromina, Ala; Besso, María José; Valentini, Chiara; Pfeifer, Manuel; Overgaard, Jens; Zips, Daniel; Kurth, Ina; Krause, Mechthild; Baumann, Michael
细胞生物学
肿瘤
肿瘤免疫
发表日期：2023
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Polyphenols as Potential Protectors against Radiation-Induced Adverse Effects in Patients with Thoracic Cancer

多酚类物质作为胸部癌症患者预防辐射诱发不良反应的潜在保护剂

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers15092412
Prades-Sagarra, Èlia; Yaromina, Ala; Dubois, Ludwig J
肿瘤
肿瘤免疫
发表日期：2023
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Homologous Recombination Deficiency Scar: Mutations and Beyond-Implications for Precision Oncology

同源重组缺陷瘢痕：突变及其他——对精准肿瘤学的启示

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers14174157
van der Wiel, Alexander M A; Schuitmaker, Lesley; Cong, Ying; Theys, Jan; Van Hoeck, Arne; Vens, Conchita; Lambin, Philippe; Yaromina, Ala; Dubois, Ludwig J
肿瘤
肿瘤免疫
发表日期：2022
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Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy

利用抗PD-L1抗体解除肿瘤免疫的抑制，并利用L19-IL2抗体加速肿瘤免疫反应，联合放射疗法可治愈免疫原性较差的肿瘤。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2020-001764
Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander Ma; Lieuwes, Natasja G; Biemans, Rianne; Lieverse, Relinde Iy; Neri, Dario; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe
肿瘤
IL2
肿瘤免疫
PD-L1
免疫/内分泌
发表日期：2021
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Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy

带电粒子和常规放射疗法：作为免疫疗法合作伙伴的当前意义

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers13061468
Marcus, Damiënne; Lieverse, Relinde I Y; Klein, Carmen; Abdollahi, Amir; Lambin, Philippe; Dubois, Ludwig J; Yaromina, Ala
免疫/内分泌
发表日期：2021
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