Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation
新型Pt@PCN-Cu诱导的铜凋亡通过线粒体HK2介导的PD-L1上调增强αPD-L1免疫疗法在胰腺导管腺癌中的疗效
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-025-03409-4
Pengyu Wang #,Weihua Guo #,Shuyue Liu #,Shouyi Li #,Jiaqi Li,Bowen Ding,Fengyi Yin,Yang Yang,Xingjiang Li,Pei Cao,Chaozhe Ma,Wanying Zhang,Yidan Song,Yating Geng,Lantao Liu,Jing Hu,Jihui Hao,Yukuan Feng
胰腺癌
肿瘤
表观遗传
免疫/内分泌
PD-L1
凋亡
线粒体
