日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Expansion of preexisting cancer driver mutant clones is induced by the genotoxic carcinogen benzo[b]fluoranthene in MutaMouse lung.

在 MutaMouse 肺中，基因毒性致癌物苯并[b]荧蒽可诱导预先存在的癌症驱动突变克隆的扩增。

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfag030
Faske Jennifer B, Gong Binsheng, LeBlanc Danielle P, Funk Juergen, Zhou Gu, Kehm Sabrina, White Paul A, Robison Timothy, Zeller Andreas, Yauk Carole L, Marchetti Francesco, Parsons Barbara L
Mouse
肿瘤
毒理研究
肿瘤免疫
发表日期：2026
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Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment

应用纠错测序技术进行体内调控性诱变性评估

期刊:Regulatory Toxicology and Pharmacology
影响因子:3.5
doi:10.1016/j.yrtph.2025.105985
Yauk, Carole L; Lynch, Anthony M; Dobrovolsky, Vasily N; Schuler, Maik; Smith-Roe, Stephanie L; Fitzgerald, Devon; Higgins, Jake; Honarvar, Naveed; Le Curieux, Frank; Matsumura, Shoji; Minocherhomji, Sheroy; Recio, Leslie; Salk, Jesse J; Sugiyama, Kei-Ichi; Suzuki, Takayoshi; Wills, John W; Marchetti, Francesco
信号转导
Sequencing
发表日期：2026
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Cisplatin Exposure Dysregulates Insulin Secretion in Male and Female Mice.

顺铂暴露会扰乱雄性和雌性小鼠的胰岛素分泌

期刊:Diabetes
影响因子:7.5
doi:10.2337/db24-0419
Basu Lahari, Grieco-St-Pierre Lili, Ching Ma Enrica Angela, Stead John D H, Hanson Antonio A, Palaniyandi Jana, van Zyl Erin, Hoyeck Myriam P, McKay Kelsea S, van Allen Kyle A, Lee Hyojin, Dai Xiao-Qing, Bautista Austin, Fadzeyeva Evgenia, Mulvihill Erin E, Yauk Carole L, Mennigen Jan A, MacDonald Patrick E, Bruin Jennifer E
代谢
发表日期：2025
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Temporal analyses of germ cell mutations using the MutaMouse model support the recommended design in OECD test guideline 488.

使用 MutaMouse 模型对生殖细胞突变进行时间分析，支持 OECD 测试指南 488 中推荐的设计

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-04085-1
Zhou Gu, Williams Andrew, LeBlanc Danielle P M, Douglas George R, Yauk Carole L, Marchetti Francesco
细胞生物学
Mouse
发表日期：2025
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Identification of four mechanisms of toxicity for per- and polyfluoroalkyl substances through transcriptomic profiling in human liver spheroids exposed to 24 PFAS

通过对暴露于24种全氟烷基和多氟烷基物质（PFAS）的人类肝球体进行转录组分析，鉴定出四种PFAS的毒性机制。

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfaf075
Addicks, Greggory C; Rowan-Carroll, Andrea; Leingartner, Karen; Williams, Andrew; Meier, Mathew J; Lorusso, Luigi; Yauk, Carole L; Atlas, Ella
FAS
毒理研究
发表日期：2025
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Bioinformatic workflows for deriving transcriptomic points of departure: current status, data gaps, and research priorities

用于推导转录组起始点的生物信息学工作流程：现状、数据缺口和研究重点

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfae145
O'Brien, Jason; Mitchell, Constance; Auerbach, Scott; Doonan, Liam; Ewald, Jessica; Everett, Logan; Faranda, Adam; Johnson, Kamin; Reardon, Anthony; Rooney, John; Shao, Kan; Stainforth, Robert; Wheeler, Matthew; Dalmas Wilk, Deidre; Williams, Andrew; Yauk, Carole; Costa, Eduardo
发表日期：2025
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Duplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cells†

双链测序揭示了ENU诱导的雄性小鼠生殖细胞突变的独特特征†

期刊:Biology of Reproduction
影响因子:3
doi:10.1093/biolre/ioaf029
LeBlanc, Danielle P M; Zhou, Gu; Williams, Andrew; Meier, Matthew J; Valentine, Charles C; Salk, Jesse J; Yauk, Carole L; Marchetti, Francesco
细胞生物学
发表日期：2025
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MutSeqR: an open source R package for standardized analysis of error-corrected next-generation sequencing data in genetic toxicology

MutSeqR：一个用于遗传毒理学中错误校正的下一代测序数据标准化分析的开源R软件包

期刊:Bioinformatics Advances
影响因子:2.8
doi:10.1093/bioadv/vbaf265
Dodge, Annette E; Williams, Andrew; LeBlanc, Danielle P M; Schuster, David M; Esina, Elena; Valentine, Charles C; Salk, Jesse J; Maslov, Alex Y; Bradley, Chris; Yauk, Carole L; Marchetti, Francesco; Meier, Matthew J
发表日期：2025
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Adverse Outcome Pathway (AOP) Coaching Program-how it functions and contributes to a more harmonized approach to AOP development and construction of AOP networks with regulatory utility

不良结局路径（AOP）辅导计划——其运作方式及其对AOP开发和构建具有监管效用的AOP网络的协调一致方法的贡献

期刊:Environmental Toxicology and Chemistry
影响因子:2.8
doi:10.1093/etojnl/vgaf173
Tanabe, Shihori; Burgdorf, Tanja; Choi, Judy; Delrue, Nathalie; Edwards, Stephen W; Filipovska, Julija; FitzGerald, Rex; Halappanavar, Sabina; Hench, Virginia K; Karschnik, Travis; LaLone, Carlie; Landesmann, Brigitte; La Rocca, Cinzia; Luijten, Mirjam; Meek, Bette; O'Brien, Jason M; Perkins, Edward J; Sachana, Magdalini; Scholz, Stefan; Song, You; Tcheremenskaia, Olga; Thomas, Russell; Tollefsen, Knut Erik; Villeneuve, Daniel L; Viviani, Barbara; Whelan, Maurice; Wittwehr, Clemens; Yauk, Carole
发表日期：2025
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Gene Set Enrichment Analysis in Zebrafish Embryos Is Susceptible to False-Positive Results in the Absence of Differentially Expressed Genes

在缺乏差异表达基因的情况下，斑马鱼胚胎基因集富集分析容易出现假阳性结果

期刊:Bioinformatics and Biology Insights
影响因子:2.4
doi:10.1177/11779322251321071
Stead, John Dh; Lee, Hyojin; Williams, Andrew; Ramírez, Sergio A Cortés; Atlas, Ella; Mennigen, Jan A; O'Brien, Jason M; Yauk, Carole
发表日期：2025
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