Yayan Pang相关文献与解析，生知库 | 链接生命科学的每一步

Qiuyun Tian, Junjie Li, Bin Wu, Yayan Pang, Wenting He, Qian Xiao, Jiaojiao Wang, Lilin Yi, Na Tian, Xiuyu Shi, Lei Xia, Xin Tian, Mulan Chen, Yepeng Fan, Boqing Xu, Yuhan Tao, Weihong Song, Yehong Du, Zhifang Dong

阿尔茨海默症

乳酸化

APP

发表日期：2025

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Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease

BAG3介导的BACE1稳定性的破坏可减轻阿尔茨海默病小鼠模型中的神经病理学和记忆缺陷

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adt7981

Lei Xia ，Junjie Li ，Yayan Pang ，Chunfang Dai ，Mingliang Xu ，Yehong Du ，Qiuyun Tian ，Lilin Yi ，Bin Wu ，Mulan Chen ，Yiqiong Qiu ，Chongjie Cheng ，Yu Tian Wang ，Weihong Song ，Zhifang Dong

miR-429-3p mediates memory decline by targeting MKP-1 to reduce surface GluA1-containing AMPA receptors in a mouse model of Alzheimer's disease

miR-429-3p 通过靶向 MKP-1 减少阿尔茨海默病小鼠模型中含有 GluA1 的表面 AMPA 受体来介导记忆力下降

期刊:Acta Pharmaceutica Sinica B

影响因子:14.7

doi:10.1016/j.apsb.2023.10.015

Man Luo, Yayan Pang, Junjie Li, Lilin Yi, Bin Wu, Qiuyun Tian, Yan He, Maoju Wang, Lei Xia, Guiqiong He, Weihong Song, Yehong Du, Zhifang Dong

Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

抑制NLRP3炎症小体信号通路通过增加p97介导的表面GluA1-AMPA受体促进缺氧缺血性脑损伤后的神经功能恢复

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-023-04452-5

Yuxin Chen, Xiaohuan Li, Qian Xiong, Yehong Du, Man Luo, Lilin Yi, Yayan Pang, Xiuyu Shi, Yu Tian Wang, Zhifang Dong

Hypoxia-sensing VGLL4 promotes LDHA-driven lactate production to ameliorate neuronal dysfunction in a cellular model relevant to Alzheimer's disease

缺氧感应 VGLL4 促进 LDHA 驱动的乳酸产生，从而改善与阿尔茨海默病相关的细胞模型中的神经元功能障碍

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.202301173RRR

Qiuyun Tian, Junjie Li, Bin Wu, Jiaojiao Wang, Qian Xiao, Na Tian, Lilin Yi, Man Luo, Zhaolun Li, Yayan Pang, Xiuyu Shi, Zhifang Dong

Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

干扰素调节因子 3 缺乏会破坏小鼠神经元兴奋和抑制的平衡，从而导致焦虑/抑郁样行为

期刊:Genes and Diseases

影响因子:6.9

doi:10.1016/j.gendis.2022.05.003

Junjie Li, Yayan Pang, Yehong Du, Lei Xia, Mulan Chen, Yepeng Fan, Zhifang Dong

Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage

Aagab 作为 NEDD4-1 介导的 Pten 核易位的新型调节剂，促进缺氧缺血性脑损伤后的神经恢复

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/s41418-021-00757-4

Chunfang Dai, Bin Wu, Yuxin Chen, Xiaohuan Li, Yanrui Bai, Yehong Du, Yayan Pang, Yu Tian Wang, Zhifang Dong

Dihydroartemisinin Induces O-GlcNAcylation and Improves Cognitive Function in a Mouse Model of Tauopathy

双氢青蒿素诱导 O-GlcNAc 糖基化并改善 Tau 蛋白病小鼠模型的认知功能

期刊:Journal of Alzheimers Disease

影响因子:3.4

doi:10.3233/JAD-210643

Lei Xia, Yayan Pang, Junjie Li, Bin Wu, Yehong Du, Yuxin Chen, Man Luo, Yan Wang, Zhifang Dong

TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease

TRPV1 激活可通过抑制 AMPAR 内吞作用减轻阿尔茨海默病 APP23/PS45 小鼠模型中的认知和突触可塑性障碍

期刊:Aging Cell

影响因子:8

doi:10.1111/acel.13113

Yehong Du, Min Fu, Zhilin Huang, Xin Tian, Junjie Li, Yayan Pang, Weihong Song, Yu Tian Wang, Zhifang Dong

MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer's disease models

MKP-1 减少 Aβ 生成并缓解阿尔茨海默病模型中的认知障碍

期刊:Signal Transduction and Targeted Therapy

影响因子:40.8

doi:10.1038/s41392-019-0091-4

Yehong Du, Yexiang Du, Yun Zhang, Zhilin Huang, Min Fu, Junjie Li, Yayan Pang, Peng Lei, Yu Tian Wang, Weihong Song, Guiqiong He, Zhifang Dong

APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer's disease

APP 赖氨酸 612 乳酸化可改善阿尔茨海默病中的淀粉样蛋白病理和记忆力下降

Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease

BAG3介导的BACE1稳定性的破坏可减轻阿尔茨海默病小鼠模型中的神经病理学和记忆缺陷

miR-429-3p mediates memory decline by targeting MKP-1 to reduce surface GluA1-containing AMPA receptors in a mouse model of Alzheimer's disease

miR-429-3p 通过靶向 MKP-1 减少阿尔茨海默病小鼠模型中含有 GluA1 的表面 AMPA 受体来介导记忆力下降

Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

抑制NLRP3炎症小体信号通路通过增加p97介导的表面GluA1-AMPA受体促进缺氧缺血性脑损伤后的神经功能恢复

Hypoxia-sensing VGLL4 promotes LDHA-driven lactate production to ameliorate neuronal dysfunction in a cellular model relevant to Alzheimer's disease

缺氧感应 VGLL4 促进 LDHA 驱动的乳酸产生，从而改善与阿尔茨海默病相关的细胞模型中的神经元功能障碍

Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

干扰素调节因子 3 缺乏会破坏小鼠神经元兴奋和抑制的平衡，从而导致焦虑/抑郁样行为

Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage

Aagab 作为 NEDD4-1 介导的 Pten 核易位的新型调节剂，促进缺氧缺血性脑损伤后的神经恢复

Dihydroartemisinin Induces O-GlcNAcylation and Improves Cognitive Function in a Mouse Model of Tauopathy

双氢青蒿素诱导 O-GlcNAc 糖基化并改善 Tau 蛋白病小鼠模型的认知功能

TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease

TRPV1 激活可通过抑制 AMPAR 内吞作用减轻阿尔茨海默病 APP23/PS45 小鼠模型中的认知和突触可塑性障碍

MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer's disease models

MKP-1 减少 Aβ 生成并缓解阿尔茨海默病模型中的认知障碍