Yaying相关文献与解析，生知库 | 链接生命科学的每一步

Yue, Jingjing; Liu, Juan; Zeng, Qiuxia; Wai, Ching Man; Deng, Ban; Tong, Yihan; Zuo, Liping; Xiang, Tao; Xie, Wangyang; Zhao, Xiaobing; Lai, Juan; Liao, Jingjin; Lai, Qingqing; Xu, Liangwei; Zhu, Yating; He, Juan; Zhang, Mingjing; Nie, Suyue; Lin, Zeng; Liang, Yanqing; Jiang, Shaolian; Chen, Xi; Wang, Bowei; Huang, Yongji; Xu, Yi; Nguyen-Edquilang, Julie; Ma, Yaying; Fumia, Nathan; Jones, Tyler; Quesada-Rojas, Patricia; Mora-Newcomer, Eric; Zhang, Jisen; Yu, Qingyi; Wang, Ming-Li; Ming, Ray

发表日期：2026

文献求助收藏

Targeting oncogenic K-RAS mutants with small-molecule degrader XMU-MP-9 through NEDD4-1.

利用小分子降解剂 XMU-MP-9 通过 NEDD4-1 靶向致癌 K-RAS 突变体。

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2025.07.031

Zeng Taoling, Jiang Tingting, Zhang Baoding, Zhang Ting, Dai Wanjun, Yin Xun, Li Yunzhan, Yu Zhuoran, Wu Caiming, Wu Yaying, Chi Ximin, Deng Xianming, Wang Hong-Rui

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

PROTAC介导的HMGCR耗竭通过铁死亡重编程乳腺癌细胞的脂质代谢，从而增强光免疫疗法的疗效。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202521525

Su, Tong; Li, Guang; Guan, Yudong; Tian, Qi; Qi, Youzhi; Zhang, Yanqiu; Wei, Wenqian; Duan, Xinxin; Rui, Jiaxin; Zhu, Hongyan; Lin, Zengping; Xie, Changchuan; Xu, Zheni; Wu, Yaying; Peng, Xin; Wang, Zhenjie; Chen, Kun; Xin, Xiaoyan; Zhang, Bing

Tumor cell-derived IFN spatially reprograms osteopontin-enriched macrophage niches to promote PARP inhibitor resistance

肿瘤细胞来源的干扰素通过空间重编程富含骨桥蛋白的巨噬细胞微环境，促进PARP抑制剂耐药性的产生。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI199035

Liu, Dan; Tao, Kangjia; Xu, Cheng; Yang, Wen; Cai, Chujun; Feng, Cui; Xiong, Kairong; Wu, Sisi; Lin, Yaying; Peng, Zikun; Chi, Jianhua; Pan, Wen; Zhong, Qing; Liu, Jiahao; Li, Xiong; Liu, Xingzhe; Zhou, Dongchen; Ma, Ding; Zhao, Guang-Nian; Xia, Yu; Fang, Yong; Gao, Qinglei

Potential regulators and metabolic networks of muscle fatty infiltration: genomic and radiomics investigation based on 33 300 participants.

肌肉脂肪浸润的潜在调节因子和代谢网络：基于 33300 名参与者的基因组学和放射组学研究。

期刊:International Journal of Surgery

影响因子:10.1

doi:10.1097/JS9.0000000000003523

Tan Jiale, Ding Zheci, Zheng Jinglin, Zhang Jie, Chen Xinyi, Li Zhou, Shi Luze, Chen Jiwu, Sun Yaying

代谢

发表日期：2026

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AI-driven CRISPR screening: optimizing gene editing through automation and intelligent decision support

AI驱动的CRISPR筛选：通过自动化和智能决策支持优化基因编辑

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-026-07849-0

Zhao, Yuxi; Li, Xingrui; Du, Yaying

发表日期：2026

文献求助收藏

Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine

在慢性偏头痛大鼠模型中，神经元DRD2的下调驱动小胶质细胞突触修剪，并通过促进CCL2释放导致认知缺陷。

期刊:Journal of Headache and Pain

影响因子:7.3

doi:10.1186/s10194-025-02229-3.

Yaying Yang,Xiaojian Liu,Han Wang,Haifeng Wen,Juan Zhong,Wei Zhang,Yi Xian,Yonghu Wang,Guangcheng Qin,Dunke Zhang,Lixue Chen

Rare NUP98::SETBP1 fusion transcript in a refractory adult T-cell lymphoblastic lymphoma

难治性成人T细胞淋巴母细胞淋巴瘤中罕见的NUP98::SETBP1融合转录本

期刊:American Journal of Cancer Research

影响因子:2.9

doi:10.62347/PPME9616

Chen, Xiaoyong; Wang, Linlin; Zou, Junyan; Zhou, Jihao; Zhou, Yaying; Zuo, Min; Hu, Lina; Dong, Xiaoying; Ke, Peng; Hou, Junjie

Prediction of lymph node metastasis in T1 colorectal cancer based on machine learning

基于机器学习的T1期结直肠癌淋巴结转移预测

期刊:PeerJ

影响因子:2.4

doi:10.7717/peerj.20500

Shi, Suyujie; Li, Xiongwu; Li, Linjun; Zhong, Haowen; Wang, Ruoyan; Zhang, Zhenyu; Liao, Chuyi; Mao, Yun; Yang, Meijie; Yang, Yaying

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

石胆酸与TULP3结合，激活sirtuins和AMPK，从而延缓衰老。

期刊:Nature

影响因子:50.5

doi:10.1038/s41586-024-08348-2

Qi Qu #,Yan Chen #,Yu Wang #,Weiche Wang #,Shating Long,Heng-Ye Yang,Jianfeng Wu,Mengqi Li,Xiao Tian,Xiaoyan Wei,Yan-Hui Liu,Shengrong Xu,Jinye Xiong,Chunyan Yang,Zhenhua Wu,Xi Huang,Changchuan Xie,Yaying Wu,Zheni Xu,Cixiong Zhang,Baoding Zhang,Jin-Wei Feng,Junjie Chen,Yuanji Feng,Huapan Fang,Liyun Lin,Z K Xie,Beibei Sun,Huayu Tian,Yong Yu,Hai-Long Piao,Xiao-Song Xie,Xianming Deng,Chen-Song Zhang,Sheng-Cai Lin

Recreating viable YY(h) genotype uncovers the role of CpYYL underlying YY lethality in papaya

重现可存活的YY(h)基因型揭示了CpYYL在番木瓜YY致死性中的作用

Targeting oncogenic K-RAS mutants with small-molecule degrader XMU-MP-9 through NEDD4-1.

利用小分子降解剂 XMU-MP-9 通过 NEDD4-1 靶向致癌 K-RAS 突变体。

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

PROTAC介导的HMGCR耗竭通过铁死亡重编程乳腺癌细胞的脂质代谢，从而增强光免疫疗法的疗效。

Tumor cell-derived IFN spatially reprograms osteopontin-enriched macrophage niches to promote PARP inhibitor resistance

肿瘤细胞来源的干扰素通过空间重编程富含骨桥蛋白的巨噬细胞微环境，促进PARP抑制剂耐药性的产生。

Potential regulators and metabolic networks of muscle fatty infiltration: genomic and radiomics investigation based on 33 300 participants.

肌肉脂肪浸润的潜在调节因子和代谢网络：基于 33300 名参与者的基因组学和放射组学研究。

AI-driven CRISPR screening: optimizing gene editing through automation and intelligent decision support

AI驱动的CRISPR筛选：通过自动化和智能决策支持优化基因编辑

Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine

在慢性偏头痛大鼠模型中，神经元DRD2的下调驱动小胶质细胞突触修剪，并通过促进CCL2释放导致认知缺陷。

Rare NUP98::SETBP1 fusion transcript in a refractory adult T-cell lymphoblastic lymphoma

难治性成人T细胞淋巴母细胞淋巴瘤中罕见的NUP98::SETBP1融合转录本

Prediction of lymph node metastasis in T1 colorectal cancer based on machine learning

基于机器学习的T1期结直肠癌淋巴结转移预测

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

石胆酸与TULP3结合，激活sirtuins和AMPK，从而延缓衰老。