Ye Wenlei相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Epitope Tagging with Genome Editing in Mice Reveals That the Proton Channel OTOP1 Is Apically Localized and Not Restricted to Type III "Sour" Taste Receptor Cells

利用基因组编辑技术对小鼠进行表位标记发现，质子通道 OTOP1 定位于细胞顶端，并不局限于 III 型“酸味”受体细胞。

期刊:Journal of Neuroscience

doi:10.1523/JNEUROSCI.1560-24.2024

Kaplan, Joshua P; Ye, Wenlei; Kileen, Heather; Liang, Ziyu; Tran, Anne; Chi, Jingyi; Yang, Chingwen; Cohen, Paul; Liman, Emily R

细胞生物学

发表日期：2025

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Molecular Pharmacology of Selective Na(V)1.6 and Dual Na(V)1.6/Na(V)1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo

选择性Na(V)1.6和双重Na(V)1.6/Na(V)1.2通道抑制剂的分子药理学研究：体外抑制兴奋性神经元活动

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.3c00757

Goodchild, Samuel J; Shuart, Noah Gregory; Williams, Aaron D; Ye, Wenlei; Parrish, R Ryley; Soriano, Maegan; Thouta, Samrat; Mezeyova, Janette; Waldbrook, Matthew; Dean, Richard; Focken, Thilo; Ghovanloo, Mohammad-Reza; Ruben, Peter C; Scott, Fiona; Cohen, Charles J; Empfield, James; Johnson, J P

发表日期：2024

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Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease

编码钙激活氯离子通道的ANO1基因的罕见变异会使人易患烟雾病。

影响因子:11.7

doi:10.1093/brain/awad172

Pinard, Amélie; Ye, Wenlei; Fraser, Stuart M; Rosenfeld, Jill A; Pichurin, Pavel; Hickey, Scott E; Guo, Dongchuan; Cecchi, Alana C; Boerio, Maura L; Guey, Stéphanie; Aloui, Chaker; Lee, Kwanghyuk; Kraemer, Markus; Alyemni, Saleh Omar; Bamshad, Michael J; Nickerson, Deborah A; Tournier-Lasserve, Elisabeth; Haider, Shozeb; Jin, Sheng Chih; Smith, Edward R; Kahle, Kristopher T; Jan, Lily Yeh; He, Mu; Milewicz, Dianna M

发表日期：2023

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Activation and closed-state inactivation mechanisms of the human voltage-gated K(V)4 channel complexes.

人类电压门控 K(V)4 通道复合物的激活和关闭状态失活机制

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2022.04.032

Ye Wenlei, Zhao Hongtu, Dai Yaxin, Wang Yingdi, Lo Yu-Hua, Jan Lily Yeh, Lee Chia-Hsueh

发表日期：2022

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Case report: Olaparib as an experimental therapy in a BRCA2-mutated patient with metastatic ovarian adenocarcinoma that originated from liver cancer

病例报告：奥拉帕尼作为一种实验性疗法，用于治疗一名携带 BRCA2 突变、原发于肝癌的转移性卵巢腺癌患者

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2022.1010158

Li, Caixia; Ye, Wenlei; Zhou, Wenni; Ye, Zhikang; Yang, Weihong; Cheng, Zhongping

发表日期：2022

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Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity

TMEM16F渗透途径中静电场的动态变化会改变其离子选择性

影响因子:6.4

doi:10.7554/eLife.45187

Ye, Wenlei; Han, Tina W; He, Mu; Jan, Yuh Nung; Jan, Lily Yeh

发表日期：2019

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An evolutionarily conserved gene family encodes proton-selective ion channels

一个进化上保守的基因家族编码质子选择性离子通道。

影响因子:45.8

doi:10.1126/science.aao3264

Tu, Yu-Hsiang; Cooper, Alexander J; Teng, Bochuan; Chang, Rui B; Artiga, Daniel J; Turner, Heather N; Mulhall, Eric M; Ye, Wenlei; Smith, Andrew D; Liman, Emily R

发表日期：2018

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Cryo-EM structures of the TMEM16A calcium-activated chloride channel

TMEM16A钙激活氯离子通道的冷冻电镜结构

影响因子:48.5

doi:10.1038/nature25024

Dang, Shangyu; Feng, Shengjie; Tien, Jason; Peters, Christian J; Bulkley, David; Lolicato, Marco; Zhao, Jianhua; Zuberbühler, Kathrin; Ye, Wenlei; Qi, Lijun; Chen, Tingxu; Craik, Charles S; Jan, Yuh Nung; Minor, Daniel L Jr; Cheng, Yifan; Jan, Lily Yeh

发表日期：2017

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The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction

钾离子通道KIR2.1与质子内流协同作用，介导酸味信号转导。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1514282112

Ye, Wenlei; Chang, Rui B; Bushman, Jeremy D; Tu, Yu-Hsiang; Mulhall, Eric M; Wilson, Courtney E; Cooper, Alexander J; Chick, Wallace S; Hill-Eubanks, David C; Nelson, Mark T; Kinnamon, Sue C; Liman, Emily R

发表日期：2016

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A proton current associated with sour taste: distribution and functional properties

与酸味相关的质子流：分布和功能特性

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.14-265694

Bushman, Jeremy D; Ye, Wenlei; Liman, Emily R

发表日期：2015

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