日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of an APC and TP53-based duplex sequencing assay to positively predict colorectal cancer response to anti-EGFR therapy

开发一种基于APC和TP53的双链测序检测方法,以积极预测结直肠癌对EGFR抑制剂治疗的反应

Yang, Mingli; Schell, Michael J; Salk, Jesse J; Higgins, Jake; Hipp, Michael; Pflieger, Lance; Pledger, Warren Jack; Yeatman, Timothy J

Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer

将脂质组学与靶向、单细胞和空间转录组学相结合,揭示了结肠癌中尚未解决的促炎状态。

Soundararajan, Ramani; Maurin, Michelle M; Rodriguez-Silva, Jetsen; Upadhyay, Gunjan; Alden, Ashley J; Gowda, Siddabasave Gowda B; Schell, Michael J; Yang, Mingli; Levine, Noah Jhad; Gowda, Divyavani; Sundaraswamy, Punith M; Hui, Shu-Ping; Pflieger, Lance; Wang, Heiman; Marcet, Jorge; Martinez, Carolina; Bennett, Robert David; Chudzinski, Allen; Karachristos, Andreas; Nywening, Timothy M; Cavallaro, Paul M; Anderson, Matthew Linley; Coffey, Robert J; Nebozhyn, Michael V; Loboda, Andrey; Coppola, Domenico; Pledger, Warren Jackson; Halade, Ganesh V; Yeatman, Timothy J

Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer

明确肿瘤上皮与肿瘤微环境在结直肠癌预后和预测中的不同作用

Yang, Mingli; Nebozhyn, Michael V; Schell, Michael J; Gandhi, Nishant; Pflieger, Lance; Loboda, Andrey; Pledger, W Jack; Soundararajan, Ramani; Maurin, Michelle; Wang, Heiman; Silva, Jetsen Rodriguez; Alden, Ashley; Coppola, Domenico; Elliott, Andrew; Sledge, George; Khushman, Moh'd; Lou, Emil; Goel, Sanjay; Yeatman, Timothy J

p21 Protein Outperforms Clinico-pathological Criteria in Predicting Liver Metastases in Pancreatic Endocrine Tumors

p21蛋白在预测胰腺内分泌肿瘤肝转移方面优于临床病理标准

Nasir, Aejaz; Ahmed, Malik K; Saller, James J; Henderson-Jackson, Evita B; Malafa, Mokenge P; Yeatman, Timothy J; Coppola, Domenico

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

lncRNA MIR100HG 与 hnRNPA2B1 的相互作用促进 m(6)A 依赖性的 TCF7L2 mRNA 稳定和结直肠癌进展

Liu, Hao; Li, Danxiu; Sun, Lina; Qin, Hongqiang; Fan, Ahui; Meng, Lingnan; Graves-Deal, Ramona; Glass, Sarah E; Franklin, Jeffrey L; Liu, Qi; Wang, Jing; Yeatman, Timothy J; Guo, Hao; Zong, Hong; Jin, Shuilin; Chen, Zhiyu; Deng, Ting; Fang, Ying; Li, Cunxi; Karijolich, John; Patton, James G; Wang, Xin; Nie, Yongzhan; Fan, Daiming; Coffey, Robert J; Zhao, Xiaodi; Lu, Yuanyuan

An integrative gene expression signature analysis identifies CMS4 KRAS-mutated colorectal cancers sensitive to combined MEK and SRC targeted therapy

整合基因表达特征分析可识别对MEK和SRC联合靶向治疗敏感的CMS4 KRAS突变型结直肠癌。

Yang, Mingli; Davis, Thomas B; Pflieger, Lance; Nebozhyn, Michael V; Loboda, Andrey; Wang, Heiman; Schell, Michael J; Thota, Ramya; Pledger, W Jack; Yeatman, Timothy J

APC and TP53 Mutations Predict Cetuximab Sensitivity across Consensus Molecular Subtypes

APC和TP53突变可预测共识分子亚型对西妥昔单抗的敏感性

Thota, Ramya; Yang, Mingli; Pflieger, Lance; Schell, Michael J; Rajan, Malini; Davis, Thomas B; Wang, Heiman; Presson, Angela; Pledger, Warren Jack; Yeatman, Timothy J

Whole Genome Sequencing Analysis of a Stage IV Colon Cancer Patient with a 10-Year Disease-Free Survival following Systemic Chemotherapy/Bevacizumab

对接受全身化疗/贝伐珠单抗治疗后获得10年无病生存期的IV期结肠癌患者进行全基因组测序分析

Yeatman, Timothy J; Yang, Mingli; Coppola, Domenico

A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

对 468 例结直肠癌进行多基因突变分类,揭示了 APC 的预后作用。

Schell, Michael J; Yang, Mingli; Teer, Jamie K; Lo, Fang Yin; Madan, Anup; Coppola, Domenico; Monteiro, Alvaro N A; Nebozhyn, Michael V; Yue, Binglin; Loboda, Andrey; Bien-Willner, Gabriel A; Greenawalt, Danielle M; Yeatman, Timothy J

A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome

复合基因表达特征优化结直肠癌转移和预后的预测

Schell, Michael J; Yang, Mingli; Missiaglia, Edoardo; Delorenzi, Mauro; Soneson, Charlotte; Yue, Binglin; Nebozhyn, Michael V; Loboda, Andrey; Bloom, Gregory; Yeatman, Timothy J