JAK-STAT and IL-17 pathway dysregulation underlies persistent immune dysfunction in ART-experienced people living with HIV in Ghana
JAK-STAT 和 IL-17 通路失调是加纳接受过抗逆转录病毒治疗的 HIV 感染者持续存在免疫功能障碍的根本原因。
期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1753475
Appeaning, Mark; Magomere, Edwin; Amoako, Nana Ama Yeboaa; Kouffie, Kirk Elorm; Tapela, Kesego; Olwal, Charles Ochieng'; Amponsah, Jones Amo; Nartey, Stella; Baah-Danquah, Rosalynn; Frimpong, Salome Tettey; Quarshie, Seyram Tetteh; Efa-Quayson, Samuel; Broni, Francis; Nenyewodey, Felix E; Abugri, James; Ansa, Gloria Akosua; Bonney, Evelyn Yayra; Quashie, Peter Kojo
IL-17
HIV
信号转导
炎症/感染
JAK/STAT
微生物学
免疫/内分泌
