日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM maps of human DNA polymerase ε should be reevaluated in light of its unexpected behavior in vitro

鉴于人DNA聚合酶ε在体外表现出的意外行为,应重新评估其冷冻电镜图谱。

Roske, Johann J; Yeeles, Joseph T P

Competition for the nascent leading strand shapes the requirements for PCNA loading in the replisome.

对新生前导链的竞争决定了复制体中 PCNA 装载的要求

Fletcher Emma E, Jones Morgan L, Yeeles Joseph T P

Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol ε

人类前导链DNA聚合酶Pol ε进行子链连续合成和校正的结构基础

Roske, Johann J; Yeeles, Joseph T P

Structure of a human replisome shows the organisation and interactions of a DNA replication machine

人类复制体的结构展示了DNA复制机器的组织结构和相互作用。

Jones, Morgan L; Baris, Yasemin; Taylor, Martin Rg; Yeeles, Joseph Tp

Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.

检查点介导的 DNA 聚合酶 α 外切酶活性抑制可抵消切除驱动的复制叉崩溃

Pellicanò Grazia, Al Mamun Mohammed, Jurado-Santiago Dolores, Villa-Hernández Sara, Yin Xingyu, Giannattasio Michele, Lanz Michael C, Smolka Marcus B, Yeeles Joseph, Shirahige Katsuhiko, García-Díaz Miguel, Bermejo Rodrigo

Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex

从AddAB型解旋酶-核酸酶复合物的结构中深入了解Chi识别机制

Saikrishnan, Kayarat; Yeeles, Joseph T; Gilhooly, Neville S; Krajewski, Wojciech W; Dillingham, Mark S; Wigley, Dale B

Visualizing helicases unwinding DNA at the single molecule level

在单分子水平上可视化解旋酶解开DNA的过程

Fili, Natali; Mashanov, Gregory I; Toseland, Christopher P; Batters, Christopher; Wallace, Mark I; Yeeles, Joseph T P; Dillingham, Mark S; Webb, Martin R; Molloy, Justin E

An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleases

铁硫簇对于AddAB型解旋酶核酸酶结合断裂的DNA至关重要。

Yeeles, Joseph T P; Cammack, Richard; Dillingham, Mark S