日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Enigma of Rapamycin Dosage

雷帕霉素剂量之谜

Mukhopadhyay, Suman; Frias, Maria A; Chatterjee, Amrita; Yellen, Paige; Foster, David A

Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.

PTEN 突变肿瘤中 PI3Kα 信号的反馈抑制可通过选择性抑制 PI3Kβ 来缓解

Schwartz Sarit, Wongvipat John, Trigwell Cath B, Hancox Urs, Carver Brett S, Rodrik-Outmezguine Vanessa, Will Marie, Yellen Paige, de Stanchina Elisa, Baselga José, Scher Howard I, Barry Simon T, Sawyers Charles L, Chandarlapaty Sarat, Rosen Neal

Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells

抑制脂肪酸合成酶可诱导K-Ras驱动的癌细胞中促生存的Akt和ERK信号通路激活。

Yellen, Paige; Foster, David A

Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest.

抑制 S6 激酶可诱导 TGF-β 依赖性 G1 细胞周期阻滞,从而抑制 eIF4E 缺失引起的细胞凋亡效应

Yellen Paige, Chatterjee Amrita, Preda Angela, Foster David A

Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).

磷脂酶 D 介导营养物质输入到哺乳动物雷帕霉素靶蛋白复合物 1 (mTORC1)

Xu Limei, Salloum Darin, Medlin Phil S, Saqcena Mahesh, Yellen Paige, Perrella Benjamin, Foster David A

Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells

磷脂酶D-mTOR在人类癌细胞中对Warburg效应的需求

Toschi, Alfredo; Lee, Evan; Thompson, Sebastian; Gadir, Noga; Yellen, Paige; Drain, C Michael; Ohh, Michael; Foster, David A

Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)

G1期细胞周期进程的调控:区分限制点与营养感知细胞生长检查点

Foster, David A; Yellen, Paige; Xu, Limei; Saqcena, Mahesh