日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Local chromatin context informs transcriptional outcomes for the histone demethylase KDM5

局部染色质环境影响组蛋白去甲基化酶KDM5的转录结果。

Yheskel, Matanel; Castiglione, Melissa A; Secombe, Julie

KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons

KDM5 介导的核糖体蛋白基因转录激活改变翻译效率,从而调节神经元的线粒体代谢

Matanel Yheskel, Hayden A M Hatch, Erika Pedrosa, Bethany K Terry, Aubrey A Siebels, Xiang Yu Zheng, Laura E R Blok, Michaela Fencková, Simone Sidoli, Annette Schenck, Deyou Zheng, Herbert M Lachman, Julie Secombe

Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

邻近标记揭示了组蛋白去甲基化酶 KDM5 的体内相互作用网络

Matanel Yheskel, Simone Sidoli, Julie Secombe

Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression

间质性微小RNA miR-214可减轻炎症和多囊肾疾病的进展

Ronak Lakhia, Matanel Yheskel, Andrea Flaten, Harini Ramalingam, Karam Aboudehen, Silvia Ferrè, Laurence Biggers, Abheepsa Mishra, Christopher Chaney, Darren P Wallace, Thomas Carroll, Peter Igarashi, Vishal Patel

Modulation of polycystic kidney disease by non-coding RNAs

非编码RNA对多囊肾病的调控

Ramalingam, Harini; Yheskel, Matanel; Patel, Vishal

Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease

抗 miR-17 寡核苷酸 RGLS4326 的发现及用于治疗多囊肾病的临床前评估

Edmund C Lee, Tania Valencia, Charles Allerson, Annelie Schairer, Andrea Flaten, Matanel Yheskel, Kara Kersjes, Jian Li, Sole Gatto, Mandeep Takhar, Steven Lockton, Adam Pavlicek, Michael Kim, Tiffany Chu, Randy Soriano, Scott Davis, John R Androsavich, Salma Sarwary, Tate Owen, Julia Kaplan, Kai Li

Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth

抗 microRNA 筛选揭示 miR-17~92 簇内的 miR-17 家族是肾囊肿生长的主要驱动因素

Matanel Yheskel, Ronak Lakhia, Patricia Cobo-Stark, Andrea Flaten, Vishal Patel

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis

抑制肾脏集合管中的 microRNA 活性可导致上皮表型部分丧失和肾脏纤维化

Sachin Hajarnis, Matanel Yheskel, Darren Williams, Thomas Brefort, Bob Glaudemans, Huguette Debaix, Michel Baum, Olivier Devuyst, Vishal Patel

PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice

PPARα激动剂非诺贝特增强脂肪酸β-氧化并减轻小鼠多囊肾和肝脏疾病

Ronak Lakhia, Matanel Yheskel, Andrea Flaten, Ezekiel B Quittner-Strom, William L Holland, Vishal Patel

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

microRNA-17家族通过调节线粒体代谢促进多囊肾病进展

Sachin Hajarnis ,Ronak Lakhia ,Matanel Yheskel ,Darren Williams ,Mehran Sorourian ,Xueqing Liu ,Karam Aboudehen ,Shanrong Zhang ,Kara Kersjes ,Ryan Galasso ,Jian Li ,Vivek Kaimal ,Steven Lockton ,Scott Davis ,Andrea Flaten ,Joshua A Johnson ,William L Holland ,Christine M Kusminski ,Philipp E Scherer ,Peter C Harris ,Marie Trudel ,Darren P Wallace ,Peter Igarashi ,Edmund C Lee ,John R Androsavich ,Vishal Patel