日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling

磷脂驱动的HCV NS5A构象转换将蛋白质折叠与复制膜重塑联系起来

Bulankina, Anna V; Richter, Rebecca M; Nettles, James H; Yamane, Daisuke; Grimm, Christian; Karami, Yasaman; Stanton, Richard A; Introini, Bianca; Hermann, Jonas; Charif, Hanaa; König, Mia S; Stroß, Claudia; Ortiz, Cristina; Kraus, Nico; Wood, Daniel; Galceran, Facundo; Abele, Rupert; Maigret, Bernard; Schinazi, Raymond F; Zeuzem, Stefan; Biondi, Ricardo M; Yi, MinKyung; Tampé, Robert; Kudryashev, Mikhail; Welsch, Christoph

Multispectral Imaging Enables Characterization of Intrahepatic Macrophages in Patients With Chronic Liver Disease

多光谱成像技术可用于表征慢性肝病患者的肝内巨噬细胞

Saldarriaga, Omar A; Freiberg, Benjamin; Krishnan, Santhoshi; Rao, Arvind; Burks, Jared; Booth, Adam L; Dye, Bradley; Utay, Netanya; Ferguson, Monique; Akil, Abdellah; Yi, Minkyung; Beretta, Laura; Stevenson, Heather L

Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors

与HCV蛋白酶NS3-4A底物的扩展相互作用网络解释了缺乏对蛋白酶抑制剂的适应能力。

Dultz, Georg; Shimakami, Tetsuro; Schneider, Markus; Murai, Kazuhisa; Yamane, Daisuke; Marion, Antoine; Zeitler, Tobias M; Stross, Claudia; Grimm, Christian; Richter, Rebecca M; Bäumer, Katrin; Yi, MinKyung; Biondi, Ricardo M; Zeuzem, Stefan; Tampé, Robert; Antes, Iris; Lange, Christian M; Welsch, Christoph

Palmitoylation of Hepatitis C Virus NS2 Regulates Its Subcellular Localization and NS2-NS3 Autocleavage

丙型肝炎病毒NS2的棕榈酰化调控其亚细胞定位和NS2-NS3自切割

Wu, Ming-Jhan; Shanmugam, Saravanabalaji; Welsch, Christoph; Yi, MinKyung

HCV NS5A dimer interface residues regulate HCV replication by controlling its self-interaction, hyperphosphorylation, subcellular localization and interaction with cyclophilin A

HCV NS5A二聚体界面残基通过控制其自身相互作用、过度磷酸化、亚细胞定位以及与环孢菌素A的相互作用来调节HCV复制。

Shanmugam, Saravanabalaji; Nichols, Alyssa K; Saravanabalaji, Dhanaranjani; Welsch, Christoph; Yi, MinKyung

Detergent-resistant membrane association of NS2 and E2 during hepatitis C virus replication

丙型肝炎病毒复制过程中NS2和E2的去污剂抗性膜结合

Shanmugam, Saravanabalaji; Saravanabalaji, Dhanaranjani; Yi, MinKyung

Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry.

丝裂原活化蛋白激酶在丙型肝炎病毒的细胞进入和复制中起着截然不同的作用:MKNK1 促进细胞进入

Kim Seungtaek, Ishida Hisashi, Yamane Daisuke, Yi MinKyung, Swinney David C, Foung Steven, Lemon Stanley M

Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step

针对丙型肝炎病毒E2蛋白的中和单克隆抗体结合不连续表位,并在病毒附着后阶段抑制感染。

Sabo, Michelle C; Luca, Vincent C; Prentoe, Jannick; Hopcraft, Sharon E; Blight, Keril J; Yi, Minkyung; Lemon, Stanley M; Ball, Jonathan K; Bukh, Jens; Evans, Matthew J; Fremont, Daved H; Diamond, Michael S

Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III.

NS5A结构域III对感染性基因型1a丙型肝炎病毒产生的调控

Kim Seungtaek, Welsch Christoph, Yi MinKyung, Lemon Stanley M

Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins.

丙型肝炎病毒 NS2 蛋白通过与结构蛋白和非结构蛋白相互作用,为病毒组装提供支架

Ma Yinghong, Anantpadma Manu, Timpe Jennifer M, Shanmugam Saravanabalaji, Singh Sher M, Lemon Stanley M, Yi Minkyung