日期 影响因子
日期:
2020 年 — 2026 年
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2021
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2026
影响因子:
–

Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos

CRISPR-Cas12a 的非选择性单链 DNA 切割活性在小鼠胚胎中未引起可检测到的脱靶效应。

期刊:Protein & Cell
影响因子:12.8
doi:10.1007/s13238-021-00824-z
Wei, Yu; Zhou, Yingsi; Liu, Yajing; Ying, Wenqin; Lv, Ruiming; Zhao, Qimeng; Zhou, Haibo; Zuo, Erwei; Sun, Yidi; Yang, Hui; Zhou, Changyang
发表日期：2021
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Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

胞嘧啶碱基编辑器在小鼠胚胎中产生大量非靶向单核苷酸变异

期刊:Science
影响因子:45.8
doi:10.1126/science.aav9973
Zuo, Erwei; Sun, Yidi; Wei, Wu; Yuan, Tanglong; Ying, Wenqin; Sun, Hao; Yuan, Liyun; Steinmetz, Lars M; Li, Yixue; Yang, Hui
碱基编辑
发表日期：2019
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Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors

人类卵裂胚胎能够通过碱基编辑器进行稳健的纯合核苷酸替换。

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-019-1703-6
Zhang, Meiling; Zhou, Changyang; Wei, Yu; Xu, Chunlong; Pan, Hong; Ying, Wenqin; Sun, Yidi; Sun, Yun; Xiao, Qingquan; Yao, Ning; Zhong, Wanxia; Li, Yun; Wu, Keliang; Yuan, Gao; Mitalipov, Shoukhrat; Chen, Zi-Jiang; Yang, Hui
Human
碱基编辑
发表日期：2019
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One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

利用CRISPR/Cas9介导的基因编辑技术，通过多个sgRNA一步构建完全基因敲除小鼠和猴子

期刊:Cell Research
影响因子:25.9
doi:10.1038/cr.2017.81
Zuo, Erwei; Cai, Yi-Jun; Li, Kui; Wei, Yu; Wang, Bang-An; Sun, Yidi; Liu, Zhen; Liu, Jiwei; Hu, Xinde; Wei, Wei; Huo, Xiaona; Shi, Linyu; Tang, Cheng; Liang, Dan; Wang, Yan; Nie, Yan-Hong; Zhang, Chen-Chen; Yao, Xuan; Wang, Xing; Zhou, Changyang; Ying, Wenqin; Wang, Qifang; Chen, Ren-Chao; Shen, Qi; Xu, Guo-Liang; Li, Jinsong; Sun, Qiang; Xiong, Zhi-Qi; Yang, Hui
发表日期：2017
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CRISPR/Cas9-mediated targeted chromosome elimination.

CRISPR/Cas9介导的靶向染色体消除

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-017-1354-4
Zuo Erwei, Huo Xiaona, Yao Xuan, Hu Xinde, Sun Yidi, Yin Jianhang, He Bingbing, Wang Xing, Shi Linyu, Ping Jie, Wei Yu, Ying Wenqin, Wei Wei, Liu Wenjia, Tang Cheng, Li Yixue, Hu Jiazhi, Yang Hui
其它
发表日期：2017
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