日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BRG1 Loss Is Frequent in Lung Cancer and Transforms Lung Epithelial Cells via Transcriptional and Epigenetic Reprograming

BRG1缺失在肺癌中很常见,并通过转录和表观遗传重编程改变肺上皮细胞。

Tessema, Mathewos; Yingling, Christin M; Phillips, Loryn M; Do, Kieu; Picchi, Maria A; Willink, Randy; Belinsky, Steven A

Inhalation delivery dramatically improves the efficacy of topotecan for the treatment of local and distant lung cancer

吸入给药可显著提高拓扑替康治疗局部和远处肺癌的疗效。

Kuehl, Philip J; Yingling, Christin M; Dubose, Devon; Burke, Michael; Revelli, David A; Chen, Wenshu; Dye, Wendy W; Belinsky, Steven A; Tessema, Mathewos

Cytotoxicity and Genotoxicity of E-Cigarette Generated Aerosols Containing Diverse Flavoring Products and Nicotine in Oral Epithelial Cell Lines

含有多种香料和尼古丁的电子烟气溶胶对口腔上皮细胞系的细胞毒性和遗传毒性

Tellez, Carmen S; Juri, Daniel E; Phillips, Loryn M; Do, Kieu; Yingling, Christin M; Thomas, Cindy L; Dye, Wendy W; Wu, Guodong; Kishida, Shosei; Kiyono, Tohru; Belinsky, Steven A

Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patients

识别新型表观遗传异常作为吸烟者和慢性阻塞性肺病患者痰液中肺癌风险的生物标志物

Tessema, Mathewos; Tassew, Dereje D; Yingling, Christin M; Do, Kieu; Picchi, Maria A; Wu, Guodong; Petersen, Hans; Randell, Scott; Lin, Yong; Belinsky, Steven A; Tesfaigzi, Yohannes

Common cancer-driver mutations and their association with abnormally methylated genes in lung adenocarcinoma from never-smokers

常见癌症驱动突变及其与非吸烟者肺腺癌中异常甲基化基因的关联

Tessema, Mathewos; Rossi, Michael R; Picchi, Maria A; Yingling, Christin M; Lin, Yong; Ramalingam, Suresh S; Belinsky, Steven A

Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer

CCDC37 和 MAP1B 的表观遗传抑制将慢性阻塞性肺病与肺癌联系起来

Tessema, Mathewos; Yingling, Christin M; Picchi, Maria A; Wu, Guodong; Liu, Yushi; Weissfeld, Joel L; Siegfried, Jill M; Tesfaigzi, Yohannes; Belinsky, Steven A

GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.

GATA2 在人类和小鼠肺肿瘤中受到表观遗传抑制,并且不是 KRAS 突变肺癌生存所必需的

Tessema Mathewos, Yingling Christin M, Snider Amanda M, Do Kieu, Juri Daniel E, Picchi Maria A, Zhang Xiequn, Liu Yushi, Leng Shuguang, Tellez Carmen S, Belinsky Steven A

Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers

通过全基因组分析揭示吸烟者和非吸烟者肺腺癌中表观遗传沉默的基因

Tessema, Mathewos; Yingling, Christin M; Liu, Yushi; Tellez, Carmen S; Van Neste, Leander; Baylin, Stephen S; Belinsky, Steven A

Defining a gene promoter methylation signature in sputum for lung cancer risk assessment

确定痰液中基因启动子甲基化特征以评估肺癌风险

Leng, Shuguang; Do, Kieu; Yingling, Christin M; Picchi, Maria A; Wolf, Holly J; Kennedy, Timothy C; Feser, William J; Baron, Anna E; Franklin, Wilbur A; Brock, Malcolm V; Herman, James G; Baylin, Stephen B; Byers, Tim; Stidley, Christine A; Belinsky, Steven A

HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer

HIF1α调控的XPA表达导致肺癌对顺铂耐药

Liu, Yanbin; Bernauer, Amanda M; Yingling, Christin M; Belinsky, Steven A