Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.
单核细胞和巨噬细胞会产生新型酮磷脂,在囊性纤维化中可以检测到这些新型酮磷脂,并激活过氧化物酶体增殖物激活受体-γ
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.405407
Hammond Victoria J, Morgan Alwena H, Lauder Sarah, Thomas Christopher P, Brown Sarah, Freeman Bruce A, Lloyd Clare M, Davies Jane, Bush Andrew, Levonen Anna-Liisa, Kansanen Emilia, Villacorta Luis, Chen Y Eugene, Porter Ned, Garcia-Diaz Yoel M, Schopfer Francisco J, O'Donnell Valerie B