日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

WBP2 Attenuates Metformin Response in HER2-Positive Breast Cancer Cells by Repressing AMPK Activation and Inducing a Lower AMP:ATP Ratio State Through Enhanced ATP Production

WBP2通过抑制AMPK激活并增强ATP生成，诱导较低的AMP/ATP比值，从而减弱HER2阳性乳腺癌细胞对二甲双胍的反应。

期刊:Cells
影响因子:5.2
doi:10.3390/cells15040381
Lin, Hexian; Kang, Shin-Ae; Xie, Fei; Lim, Yvonne Xinyi; Seah, Sock Hong; Sabbaghian, Amir; Lu, Ssu-Yi; Chew, Ting Gang; Deng, Lih-Wen; Wang, Shu; Tai, E-Shyong; Lim, Yoon Pin
肿瘤
HER2
肿瘤免疫
AMPK
乳腺癌
细胞生物学
发表日期：2026
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WFIKKN2 is secreted and elevated in blood plasma of HER2-positive breast cancer patients - implications in cancer surveillance and recurrence monitoring

WFIKKN2在HER2阳性乳腺癌患者的血浆中分泌并升高——对癌症监测和复发监测具有重要意义

期刊:Biomarker Research
影响因子:11.5
doi:10.1186/s40364-025-00853-4
Sabbaghian, Amir; Xie, Fei; Wang, Xiao Fang; Yang, Zhen; Zhang, Ming Chen; Chew, Ting Gang; Wang, Shu; Lim, Yoon Pin
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Overexpression of DDR1 contributes to gastric cancer progression by inhibiting the Hippo pathway

DDR1 的过度表达通过抑制 Hippo 通路促进胃癌的进展。

期刊:Journal of Biomedical Research
影响因子:2.4
doi:10.7555/JBR.39.20250198
Han, Haiying; Shen, Tianqi; Zhou, Tingting; Yang, Yixuan; Toy, Weiyi; Choo, Yin Yin; Lin, Fan; Lim, Yoon Pin
胃癌
DDR1
肿瘤
肿瘤免疫
信号转导
Hippo
发表日期：2025
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Bioorthogonal Catalysis for Treatment of Solid Tumors Using Thermostable, Self-Assembling, Single Enzyme Nanoparticles and Natural Product Conversion with Indole-3-acetic Acid

利用耐热自组装单酶纳米粒子和吲哚-3-乙酸转化天然产物，实现生物正交催化治疗实体瘤

期刊:ACS Nano
影响因子:16
doi:10.1021/acsnano.1c11560
Sadeghi, Samira; Masurkar, Nihar D; Vallerinteavide Mavelli, Girish; Deshpande, Siddharth; Kok Yong Tan, Warren; Yee, Sherman; Kang, Shin-Ae; Lim, Yoon-Pin; Kai-Hua Chow, Edward; Drum, Chester L
发表日期：2022
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WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-κB activation.

WBP2 通过 NF-κB 激活促进 BTRC mRNA 的稳定性，从而驱动三阴性乳腺癌的迁移和侵袭

期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.13048
Lim Yvonne Xinyi, Lin Hexian, Chu Tinghine, Lim Yoon Pin
肿瘤
乳腺癌
NF-κB
发表日期：2022
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Reciprocal Regulation of Hippo and WBP2 Signalling-Implications in Cancer Therapy

Hippo 和 WBP2 信号通路的相互调控——在癌症治疗中的意义

期刊:Cells
影响因子:5.2
doi:10.3390/cells10113130
Lim, Yvonne Xinyi; Lin, Hexian; Seah, Sock Hong; Lim, Yoon Pin
信号转导
肿瘤
肿瘤免疫
Hippo
发表日期：2021
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WBP2 inhibits microRNA biogenesis via interaction with the microprocessor complex

WBP2 通过与微处理器复合物相互作用抑制 microRNA 的生物合成

期刊:Life Science Alliance
影响因子:3.3
doi:10.26508/lsa.202101038
Hossein Tabatabaeian, Shen Kiat Lim, Tinghine Chu, Sock Hong Seah, Yoon Pin Lim
发表日期：2021
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The emerging roles of WBP2 oncogene in human cancers

WBP2癌基因在人类癌症中的新兴作用

期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-020-1318-0
Tabatabaeian, Hossein; Rao, Angad; Ramos, Alisha; Chu, Tinghine; Sudol, Marius; Lim, Yoon Pin
肿瘤
肿瘤免疫
发表日期：2020
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The transcriptional coactivator WBP2 primes triple-negative breast cancer cells for responses to Wnt signaling via the JNK/Jun kinase pathway

转录辅激活因子 WBP2 通过 JNK/Jun 激酶通路启动三阴性乳腺癌细胞对 Wnt 信号的应答

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.RA118.005796
Zilin Li, Shen Kiat Lim, Xu Liang, Yoon Pin Lim
免疫
细胞生物学
乳腺癌
肿瘤细胞
Wnt/β-Catenin
发表日期：2018
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Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2

Wnt 信号通过阻断 ITCH 介导的 YAP/TAZ 转录辅激活因子 WBP2 降解来促进乳腺癌

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-15-3537
Shen Kiat Lim, Ssu Yi Lu, Shin-Ae Kang, Hock Jin Tan, Zilin Li, Zhen Ning Adrian Wee, Jye Swei Guan, Vishnu Priyanka Reddy Chichili, J Sivaraman, Thomas Putti, Aye Aye Thike, Puay Hoon Tan, Marius Sudol, David M Virshup, Siew Wee Chan, Wanjin Hong, Yoon Pin Lim
信号转导
肿瘤
乳腺癌
Wnt/β-Catenin
发表日期：2016
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