日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The vaccinia chondroitin sulfate binding protein drives host membrane curvature to facilitate fusion

牛痘硫酸软骨素结合蛋白驱动宿主膜曲率以促进融合

Laura Pokorny, Jemima J Burden, David Albrecht, Rebecca Bamford, Kendra E Leigh, Pooja Sridhar, Timothy J Knowles, Yorgo Modis, Jason Mercer

Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing

对比 MDA5 和 LGP2 在病毒 RNA 传感中的 ATP 水解功能

Rahul Singh, Yuan Wu, Alba Herrero Del Valle, Kendra E Leigh, Sai Mong, Mark T K Cheng, Brian J Ferguson, Yorgo Modis

Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization

NLRP3 激活的 ASC 复合物的低温电子断层扫描揭示了细胞器共定位

Yangci Liu, Haoming Zhai, Helen Alemayehu, Jérôme Boulanger, Lee J Hopkins, Alicia C Borgeaud, Christina Heroven, Jonathan D Howe, Kendra E Leigh, Clare E Bryant, Yorgo Modis

A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus

钩虫内源性病毒中具有生物活性的类白蛉病毒包膜蛋白

Monique Merchant, Carlos P Mata, Yangci Liu, Haoming Zhai, Anna V Protasio, Yorgo Modis

Structure and functional mapping of the KRAB-KAP1 repressor complex

KRAB-KAP1 阻遏物复合物的结构和功能映射

Guido A Stoll, Ninoslav Pandiloski, Christopher H Douse, Yorgo Modis

MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA

MDA5 疾病变体 M854K 阻止 ATP 依赖的病毒和细胞 RNA 结构识别

Qin Yu #, Alba Herrero Del Valle #, Rahul Singh #, Yorgo Modis

Periphilin self-association underpins epigenetic silencing by the HUSH complex

Periphilin 自身缔合是 HUSH 复合物表观遗传沉默的基础

Daniil M Prigozhin, Christopher H Douse, Laura E Farleigh, Anna Albecka, Iva A Tchasovnikarova, Richard T Timms, Shun-Ichiro Oda, Frank Adolf, Stefan M V Freund, Sarah Maslen, Paul J Lehner, Yorgo Modis

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

TASOR 是一种伪 PARP,可指导 HUSH 复合物组装和表观遗传转座子控制

Christopher H Douse #, Iva A Tchasovnikarova #, Richard T Timms #, Anna V Protasio, Marta Seczynska, Daniil M Prigozhin, Anna Albecka, Jane Wagstaff, James C Williamson, Stefan M V Freund, Paul J Lehner, Yorgo Modis

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

人类白细胞介素-2受体β突变与免疫缺陷和外周耐受性相关

Zinan Zhang #,Florian Gothe #,Perrine Pennamen #,John R James,David McDonald,Carlos P Mata,Yorgo Modis,Anas M Alazami,Meghan Acres,Wolfram Haller,Claire Bowen,Rainer Döffinger,Jan Sinclair,Shannon Brothers,Yu Zhang,Helen F Matthews,Sophie Naudion,Fanny Pelluard,Huda Alajlan,Yasuhiro Yamazaki,Luigi D Notarangelo,James E Thaventhiran,Karin R Engelhardt,Hamoud Al-Mousa,Sophie Hambleton #,Caroline Rooryck #,Kenneth G C Smith #,Michael J Lenardo #

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

KAP1 三部分基序的结构识别逆转录因子沉默所需的分子界面

Guido A Stoll, Shun-Ichiro Oda, Zheng-Shan Chong, Minmin Yu, Stephen H McLaughlin, Yorgo Modis