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A positive cytokine/chemokine feedback loop establishes plasmacytoid DC-driven autoimmune pancreatitis in IgG4-related disease.

IgG4 相关疾病中，细胞因子/趋化因子正反馈回路导致浆细胞样树突状细胞驱动的自身免疫性胰腺炎

doi:10.1172/jci.insight.167910

Hara Akane, Watanabe Tomohiro, Minaga Kosuke, Yoshikawa Tomoe, Kurimoto Masayuki, Sekai Ikue, Masuta Yasuhiro, Takada Ryutaro, Otsuka Yasuo, Kamata Ken, Takamura Shiki, Kudo Masatoshi, Strober Warren

Activation of the aryl hydrocarbon receptor inhibits the development of experimental autoimmune pancreatitis through IL-22-mediated signaling pathways

芳烃受体的激活通过IL-22介导的信号通路抑制实验性自身免疫性胰腺炎的发展。

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1093/cei/uxad040

Kamata, Ken; Hara, Akane; Minaga, Kosuke; Yoshikawa, Tomoe; Kurimoto, Masayuki; Sekai, Ikue; Okai, Natsuki; Omaru, Naoya; Masuta, Yasuhiro; Otsuka, Yasuo; Takada, Ryutaro; Takamura, Shiki; Kudo, Masatoshi; Strober, Warren; Watanabe, Tomohiro

Leucine-rich repeat kinase 2 promotes the development of experimental severe acute pancreatitis

富含亮氨酸重复激酶2促进实验性重症急性胰腺炎的发展

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1093/cei/uxad106

Otsuka, Yasuo; Hara, Akane; Minaga, Kosuke; Sekai, Ikue; Kurimoto, Masayuki; Masuta, Yasuhiro; Takada, Ryutaro; Yoshikawa, Tomoe; Kamata, Ken; Kudo, Masatoshi; Watanabe, Tomohiro

Azaphilones produced by Penicillium maximae with their cell death-inducing activity on Adriamycin-treated cancer cell

大青霉产生的阿扎菲酮对经阿霉素处理的癌细胞具有细胞死亡诱导活性

期刊:Genes and Environment

影响因子:2.7

doi:10.1186/s41021-023-00261-w

Takahiro Matsumoto, Erika Ohnishi, Takahiro Kitagawa, Masaya Okayama, Youhei Saito, Hayato Yoshikawa, Tomoe Ohta, Tatsusada Yoshida, Yuji Nakayama, Tetsushi Watanabe

Low-dose gemcitabine plus nab-paclitaxel versus standard-dose gemcitabine plus nab-paclitaxel in elderly patients with metastatic pancreatic cancer: A randomized Phase II trial

低剂量吉西他滨联合白蛋白紫杉醇与标准剂量吉西他滨联合白蛋白紫杉醇治疗老年转移性胰腺癌患者的疗效比较：一项随机II期试验

期刊:JGH Open

影响因子:1.5

doi:10.1002/jgh3.12966

Kamata, Ken; Imai, Hajime; Matsumoto, Hisakazu; Yamashita, Yukitaka; Kato, Takao; Nishi, Katsuhisa; Omoto, Shunsuke; Minaga, Kosuke; Yamao, Kentaro; Hyodo, Tomoko; Im, Sung-Woon; Hara, Akane; Yoshikawa, Tomoe; Ishikawa, Rei; Okamoto, Ayana; Yamazaki, Tomohiro; Nakai, Atsushi; Ueshima, Kazuomi; Chiba, Yasutaka; Takenaka, Mamoru; Watanabe, Tomohiro; Kitano, Masayuki; Kudo, Masatoshi

Utility of contrast-enhanced harmonic EUS for diagnosis of portal vein invasion by pancreatic cancer

对比增强谐波超声内镜在胰腺癌门静脉侵犯诊断中的应用价值

期刊:Endoscopic Ultrasound

影响因子:5.4

doi:10.4103/EUS-D-21-00185

Nakai, Atsushi; Kamata, Ken; Hyodo, Tomoko; Chikugo, Takaaki; Hara, Akane; Otsuka, Yasuo; Tanaka, Hidekazu; Yoshikawa, Tomoe; Ishikawa, Rei; Okamoto, Ayana; Yamazaki, Tomohiro; Omoto, Shunsuke; Minaga, Kosuke; Yamao, Kentaro; Takenaka, Mamoru; Chiba, Yasutaka; Watanabe, Tomohiro; Matsumoto, Ippei; Takeyama, Yoshifumi; Kudo, Masatoshi

Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4

细胞凋亡抑制蛋白和致结肠炎细胞因子的表达水平与干扰素调节因子4的激活呈负相关

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1093/cei/uxac005

Masaki, Sho; Watanabe, Tomohiro; Arai, Yasuyuki; Sekai, Ikue; Hara, Akane; Kurimoto, Masayuki; Otsuka, Yasuo; Masuta, Yasuhiro; Yoshikawa, Tomoe; Takada, Ryutaro; Kamata, Ken; Minaga, Kosuke; Yamashita, Kouhei; Kudo, Masatoshi

Bispectral index-guided propofol sedation during endoscopic ultrasonography

双频指数引导下丙泊酚镇静内镜超声检查

期刊:Clinical Endoscopy

影响因子:2.3

doi:10.5946/ce.2022.001

Okamoto, Ayana; Kamata, Ken; Miyata, Takeshi; Yoshikawa, Tomoe; Ishikawa, Rei; Yamazaki, Tomohiro; Nakai, Atsushi; Omoto, Shunsuke; Minaga, Kosuke; Yamao, Kentaro; Takenaka, Mamoru; Chiba, Yasutaka; Sakurai, Toshiharu; Nishida, Naoshi; Kitano, Masayuki; Kudo, Masatoshi

发表日期：2022

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Intestinal Dysbiosis and Autoimmune Pancreatitis

肠道菌群失调与自身免疫性胰腺炎

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2021.621532

Yoshikawa, Tomoe; Watanabe, Tomohiro; Kamata, Ken; Hara, Akane; Minaga, Kosuke; Kudo, Masatoshi

Gut Microbiota Involved in the Immunopathogenesis of Autoimmune Pancreatitis

肠道菌群参与自身免疫性胰腺炎的免疫发病机制

A positive cytokine/chemokine feedback loop establishes plasmacytoid DC-driven autoimmune pancreatitis in IgG4-related disease.

IgG4 相关疾病中，细胞因子/趋化因子正反馈回路导致浆细胞样树突状细胞驱动的自身免疫性胰腺炎

Activation of the aryl hydrocarbon receptor inhibits the development of experimental autoimmune pancreatitis through IL-22-mediated signaling pathways

芳烃受体的激活通过IL-22介导的信号通路抑制实验性自身免疫性胰腺炎的发展。

Leucine-rich repeat kinase 2 promotes the development of experimental severe acute pancreatitis

富含亮氨酸重复激酶2促进实验性重症急性胰腺炎的发展

Azaphilones produced by Penicillium maximae with their cell death-inducing activity on Adriamycin-treated cancer cell

大青霉产生的阿扎菲酮对经阿霉素处理的癌细胞具有细胞死亡诱导活性

Low-dose gemcitabine plus nab-paclitaxel versus standard-dose gemcitabine plus nab-paclitaxel in elderly patients with metastatic pancreatic cancer: A randomized Phase II trial

低剂量吉西他滨联合白蛋白紫杉醇与标准剂量吉西他滨联合白蛋白紫杉醇治疗老年转移性胰腺癌患者的疗效比较：一项随机II期试验

Utility of contrast-enhanced harmonic EUS for diagnosis of portal vein invasion by pancreatic cancer

对比增强谐波超声内镜在胰腺癌门静脉侵犯诊断中的应用价值

Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4

细胞凋亡抑制蛋白和致结肠炎细胞因子的表达水平与干扰素调节因子4的激活呈负相关

Bispectral index-guided propofol sedation during endoscopic ultrasonography

双频指数引导下丙泊酚镇静内镜超声检查

Intestinal Dysbiosis and Autoimmune Pancreatitis

肠道菌群失调与自身免疫性胰腺炎