日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Phase 1, Randomized, Open-Label Study to Assess the Bioequivalence of Trofinetide as a Ready-to-Use Oral Solution and Constituted Powder for Oral Solution in Healthy Adults

一项 1 期随机、开放标签研究，旨在评估 Trofinetide 作为即用型口服溶液和口服溶液用粉剂在健康成人中的生物等效性。

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-025-03484-1
Darwish, Mona; Yamamoto, Amy; Adegbenle, Yvonne; Tejwani, Ravi; Chen, Yonghua; Nunez-Disla, Rene; Youakim, James M; Pathak, Sanjeev
发表日期：2026
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Cinnamomum cassia Alleviates Neuropsychiatric Lupus in a Murine Experimental Model.

肉桂可缓解小鼠实验模型中的神经精神性狼疮

期刊:Nutrients
影响因子:5
doi:10.3390/nu17111820
Maalouly Georges, Saliba Youakim, Hajal Joelle, Zein-El-Din Anna, Fakhoury Luana, Najem Rouaa, Smayra Viviane, Nassereddine Hussein, Fares Nassim
神经科学
发表日期：2025
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Population Pharmacokinetic Modeling to Support Trofinetide Dosing for the Treatment of Rett Syndrome

群体药代动力学模型支持托吡奈肽治疗雷特综合征的给药方案

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-024-03056-9
Darwish, Mona; Passarell, Julie; Maxwell, Kelly; Youakim, James M; Bradley, Heather; Bishop, Kathie M
发表日期：2025
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Physiologically-Based Pharmacokinetic Modeling of Trofinetide in Moderate Renal Impairment for Phase 1 Clinical Study Dose Selection with Model Validation

基于生理的中度肾功能损害患者托吡奈肽药代动力学模型在I期临床研究剂量选择中的应用及模型验证

期刊:European Journal of Drug Metabolism and Pharmacokinetics
影响因子:2.4
doi:10.1007/s13318-024-00924-1
Darwish, Mona; Marbury, Thomas C; Nunez, Rene; Youakim, James M; An, Di; Darling, Inger; Lukacova, Viera; Bishop, Kathie M
发表日期：2025
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Erythema elevatum diutinum - An atypical case presentation exposing the histopathological progression of disease

持续性隆起性红斑——一例非典型病例，揭示了该疾病的组织病理学进展

期刊:SAGE Open Medical Case Reports
影响因子:0.6
doi:10.1177/2050313X251343268
Youakim, Mina; Shah, Ahmed; Robertson, Lynne H
发表日期：2025
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Courage, hope, and transformation: Patient experiences of web-based, therapist delivered eye movement desensitization and reprocessing for suicidal ideation

勇气、希望与转变：患者接受基于网络、由治疗师提供的眼动脱敏疗法治疗自杀意念的体验

期刊:
影响因子:
doi:10.1371/journal.pmen.0000373
Yap, Sidney; Bal, Manroop; Youakim, Mina; Aborawi, Ashraf; Di Pinto, Genna; Samways, Krystle; Beck, Amy; Bright, Katherine S; Brémault-Phillips, Suzette; Greenshaw, Andrew J; Winkler, Olga; Burback, Lisa
发表日期：2025
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Inhibiting atrial natriuretic peptide clearance reduces myocardial fibrosis and improves cardiac function in diabetic rats.

抑制心房利钠肽清除可减少糖尿病大鼠的心肌纤维化并改善心脏功能

期刊:European Heart Journal Open
影响因子:
doi:10.1093/ehjopen/oeaf031
Bakhos Jules Joel, Saliba Youakim, Hajal Joelle, Achkouty Guy, Oskaridjian Hrag, Albuquerque Miguel, Azevedo Chloé, Semaan Albert, Suffee Nadine, Balse Elise, Hatem Stéphane N, Fares Nassim
心血管
糖尿病
发表日期：2025
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Exposure-Response Efficacy Modeling to Support Trofinetide Dosing in Individuals with Rett Syndrome

利用暴露-反应疗效模型支持雷特综合征患者的托非尼肽给药方案

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-024-02796-y
Darwish, Mona; Passarell, Julie; Youakim, James M; Bradley, Heather; Bishop, Kathie M
发表日期：2024
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Effect of Hepatic Impairment on Trofinetide Exposures Using an In Silico Physiologically Based Pharmacokinetic Model

利用计算机模拟生理药代动力学模型研究肝功能损害对曲非尼肽暴露量的影响

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-024-02926-6
Darwish, Mona; Obianom, Obinna N; Youakim, James M; Darling, Inger; Lukacova, Viera; Bradley, Heather
发表日期：2024
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Correction: Amin et al. Hippocampal and Cerebellar Changes in Acute Restraint Stress and the Impact of Pretreatment with Ceftriaxone. Brain Sci. 2020, 10, 193

更正：Amin 等人，《急性束缚应激下海马和小脑的变化及头孢曲松预处理的影响》，《脑科学》，2020，10，193

期刊:Brain Sciences
影响因子:2.8
doi:10.3390/brainsci14090933
Amin, Shaimaa N; Hassan, Sherif S; Khashaba, Ahmed S; Youakim, Magdy F; Latif, Noha S Abdel; Rashed, Laila A; Yassa, Hanan D
Hippo
神经科学
发表日期：2024
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