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SAT-362 Hypothalamic Pituitary Adrenal Axis Dysregulation Alters Central and Peripheral Adaptation to Repeated Stress Exposure in Mice

SAT-362 下丘脑-垂体-肾上腺轴功能紊乱会改变小鼠对重复应激暴露的中枢和外周适应性

doi:10.1136/jcp.2004.016733

Fleming, F J; Myers, E; Kelly, G; Crotty, T B; McDermott, E W; O'Higgins, N J; Hill, A D K; Young, L S; Kinlein, Scott; Wallace, Naomi; Blekkenk, Parker; Savenkova, Marina; Karatsoreos, Ilia

Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop

Fas相关因子（Faf1）是一种新型的CD40相互作用蛋白，它通过负反馈环路调节CD40诱导的NF-κB激活。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/cddis.2014.172

Elmetwali, T; Young, L S; Palmer, D H

Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

细胞FLICE抑制蛋白（c-FLIP）的表达可保护霍奇金淋巴瘤细胞免受Fas介导的自主性死亡。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.0400765101

Dutton, A; O'Neil, J D; Milner, A E; Reynolds, G M; Starczynski, J; Crocker, J; Young, L S; Murray, P G

Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954, and identification of synergism with 5-fluorouracil

新型酶-前药组合硝基还原酶/CB1954诱导细胞死亡的机制及其与5-氟尿嘧啶的协同作用

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/sj.bjc.6601211

Palmer, D H; Milner, A E; Kerr, D J; Young, L S

细胞生物学

发表日期：2003

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CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily.

CD40 通过激活肿瘤坏死因子超家族的细胞毒性配体诱导癌细胞凋亡

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/MCB.20.15.5503-5515.2000

Eliopoulos A G, Davies C, Knox P G, Gallagher N J, Afford S C, Adams D H, Young L S

CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection

CD40激活通过诱导细胞表面Fas配体表达，诱导培养的人肝细胞凋亡，并在同种异体移植排斥反应中放大Fas介导的肝细胞死亡。

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.189.2.441

Afford, S C; Randhawa, S; Eliopoulos, A G; Hubscher, S G; Young, L S; Adams, D H

Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2

Epstein-Barr病毒编码的潜伏膜蛋白1通过其C端，经由TRADD和TRAF2参与的机制激活JNK通路。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.73.2.1023-1035.1999

Eliopoulos, A G; Blake, S M; Floettmann, J E; Rowe, M; Young, L S

Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus

食管化生-异型增生-腺癌序列的分子演变

期刊:American Journal of Pathology

影响因子:3.6

doi:10.1016/S0002-9440(10)65346-1

Jankowski, J A; Wright, N A; Meltzer, S J; Triadafilopoulos, G; Geboes, K; Casson, A G; Kerr, D; Young, L S

Functional differences between BHRF1, the Epstein-Barr virus-encoded Bcl-2 homologue, and Bcl-2 in human epithelial cells

BHRF1（Epstein-Barr病毒编码的Bcl-2同源物）与人上皮细胞中的Bcl-2之间的功能差异

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.72.11.9016-9024.1998

Dawson, C W; Dawson, J; Jones, R; Ward, K; Young, L S

Multimodal AI-based risk stratification for distant metastasis in nasopharyngeal carcinoma

基于多模态人工智能的鼻咽癌远处转移风险分层

SAT-362 Hypothalamic Pituitary Adrenal Axis Dysregulation Alters Central and Peripheral Adaptation to Repeated Stress Exposure in Mice

SAT-362 下丘脑-垂体-肾上腺轴功能紊乱会改变小鼠对重复应激暴露的中枢和外周适应性

Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop

Fas相关因子（Faf1）是一种新型的CD40相互作用蛋白，它通过负反馈环路调节CD40诱导的NF-κB激活。

Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

细胞FLICE抑制蛋白（c-FLIP）的表达可保护霍奇金淋巴瘤细胞免受Fas介导的自主性死亡。

Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954, and identification of synergism with 5-fluorouracil

新型酶-前药组合硝基还原酶/CB1954诱导细胞死亡的机制及其与5-氟尿嘧啶的协同作用

CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily.

CD40 通过激活肿瘤坏死因子超家族的细胞毒性配体诱导癌细胞凋亡

CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection

CD40激活通过诱导细胞表面Fas配体表达，诱导培养的人肝细胞凋亡，并在同种异体移植排斥反应中放大Fas介导的肝细胞死亡。

Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2

Epstein-Barr病毒编码的潜伏膜蛋白1通过其C端，经由TRADD和TRAF2参与的机制激活JNK通路。

Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus

食管化生-异型增生-腺癌序列的分子演变

Functional differences between BHRF1, the Epstein-Barr virus-encoded Bcl-2 homologue, and Bcl-2 in human epithelial cells

BHRF1（Epstein-Barr病毒编码的Bcl-2同源物）与人上皮细胞中的Bcl-2之间的功能差异