日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems

活体系统中Tn/TF/STF抗原的化学酶法标记

Yang, Yi; Chen, Mingkuan; Wu, Mengyao; Hong, Senlian; Gao, Bing; Liu, Yonghui; Yu, Chenhua; Young, Travis S; Chapla, Digantkumar Gopaldas; Yang, Jeong-Yeh; Cappiello, John R; Li, Jie P; Sharpless, K Barry; Moremen, Kelley W; Wu, Peng

Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19(+) malignancy

人源CD19特异性可转换CAR T细胞与组成型活性CAR T细胞疗效相当,但在人源CD19(+)恶性肿瘤小鼠模型中引起的并发症更少。

Pennell, Christopher A; Campbell, Heather; Storlie, Meghan D; Bolivar-Wagers, Sara; Osborn, Mark J; Refaeli, Yosef; Jensen, Michael; Viaud, Sophie; Young, Travis S; Blazar, Bruce R

Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors

基于细胞的筛选方法用于发现脂多糖生物合成抑制剂

Zhang, Ge; Baidin, Vadim; Pahil, Karanbir S; Moison, Eileen; Tomasek, David; Ramadoss, Nitya S; Chatterjee, Arnab K; McNamara, Case W; Young, Travis S; Schultz, Peter G; Meredith, Timothy C; Kahne, Daniel

Structure-Activity Relationship and Molecular Mechanics Reveal the Importance of Ring Entropy in the Biosynthesis and Activity of a Natural Product

结构-活性关系和分子力学揭示了环熵在天然产物生物合成和活性中的重要性

Tran, Hai L; Lexa, Katrina W; Julien, Olivier; Young, Travis S; Walsh, Christopher T; Jacobson, Matthew P; Wells, James A

Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

靶向乳腺癌的可切换嵌合抗原受体T细胞的设计

Cao, Yu; Rodgers, David T; Du, Juanjuan; Ahmad, Insha; Hampton, Eric N; Ma, Jennifer S Y; Mazagova, Magdalena; Choi, Sei-Hyun; Yun, Hwa Young; Xiao, Han; Yang, Pengyu; Luo, Xiaozhou; Lim, Reyna K V; Pugh, Holly M; Wang, Feng; Kazane, Stephanie A; Wright, Timothy M; Kim, Chan Hyuk; Schultz, Peter G; Young, Travis S

Recombinant thiopeptides containing noncanonical amino acids

含有非天然氨基酸的重组硫肽

Luo, Xiaozhou; Zambaldo, Claudio; Liu, Tao; Zhang, Yuhan; Xuan, Weimin; Wang, Chen; Reed, Sean A; Yang, Peng-Yu; Wang, Rongsheng E; Javahishvili, Tsotne; Schultz, Peter G; Young, Travis S

Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks

三种环状翻译后修饰:将噁唑、噻唑和吡啶插入蛋白质衍生的骨架中

Walsh, Christopher T; Malcolmson, Steven J; Young, Travis S

Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants.

利用密码子随机化快速探索硫肽类抗生素变体的化学空间

Young Travis S, Dorrestein Pieter C, Walsh Christopher T

Evolution of cyclic peptide protease inhibitors

环状肽蛋白酶抑制剂的演变

Young, Travis S; Young, Douglas D; Ahmad, Insha; Louis, John M; Benkovic, Stephen J; Schultz, Peter G

Beyond the canonical 20 amino acids: expanding the genetic lexicon

超越经典的20种氨基酸:扩展遗传词汇

Young, Travis S; Schultz, Peter G