日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion

在一项I期临床试验中,通过持续静脉输注IL-15给患有实体瘤的成年患者,可诱导NK细胞亚群的显著扩增。

Conlon, Kevin C; Potter, E Lake; Pittaluga, Stefania; Lee, Chyi-Chia Richard; Miljkovic, Milos D; Fleisher, Thomas A; Dubois, Sigrid; Bryant, Bonita R; Petrus, Michael; Perera, Liyanage P; Hsu, Jennifer; Figg, William D; Peer, Cody J; Shih, Joanna H; Yovandich, Jason L; Creekmore, Stephen P; Roederer, Mario; Waldmann, Thomas A

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques.

重组人IL-15在恒河猴中的安全性(毒性)、药代动力学、免疫原性以及对正常免疫系统成分的影响

Waldmann Thomas A, Lugli Enrico, Roederer Mario, Perera Liyanage P, Smedley Jeremy V, Macallister Rhonda P, Goldman Carolyn K, Bryant Bonita R, Decker Jean M, Fleisher Thomas A, Lane H Clifford, Sneller Michael C, Kurlander Roger J, Kleiner David E, Pletcher John M, Figg William D, Yovandich Jason L, Creekmore Stephen P

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

IL-15对非人灵长类动物淋巴细胞稳态的瞬时和持续影响

Lugli, Enrico; Goldman, Carolyn K; Perera, Liyanage P; Smedley, Jeremy; Pung, Rhonda; Yovandich, Jason L; Creekmore, Stephen P; Waldmann, Thomas A; Roederer, Mario